Saturday, December 31, 2016

U.S. judge blocks transgender, abortion-related Obamacare protections

Dec 31 (Reuters) - A federal judge in Texas on Saturday

issued a court order barring enforcement of an Obama

administration policy seeking to extend anti-discrimination

protections under the Affordable Care Act to transgender health

and abortion-related services.

Read more

Braeburn Pharmaceuticals files for IPO

Dec 30 (Reuters) - Braeburn Pharmaceuticals Inc filed with

U.S. regulators on Friday to raise up to $150 million in an

initial public offering, seven months after its implant to treat

opioid addiction was approved in the United States.

Read more

Friday, December 30, 2016

BRIEF-Vitality Products Inc reports Q3 net loss per $0.00/shr

* Vitality Products Inc says for three months ended October

31, 2016 net loss per share of $0.00

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Novavax Inc files for mixed shelf of upto $125 mln - SEC filing

* Novavax Inc - files for mixed shelf of upto $125 million -

SEC filing

Source text: (http://bit.ly/2iyJ7uW)

Further company coverage:

Read more

BRIEF-Braeburn Pharmaceuticals Inc files for IPO of up to $150 mln - SEC filing

* Braeburn Pharmaceuticals Inc files for IPO of up to $150

million - SEC filing

Read more

BRIEF-Rewalk Robotics says drew down $8 mln under loan agreement with Kreos Capital

* Rewalk Robotics - in connection with $8 million drawdown,

on Dec 28, increased amount of warrant issued to Kreos on Dec

30, 2015 from $1.15 million to $1.61 million

Read more

BRIEF-Axovant Sciences files for mixed shelf of up to $750 mln - SEC filing

* Files for mixed shelf of up to $750 million - SEC filing

Source text: (http://bit.ly/2iNwLhV)

Further company coverage:

Read more

UPDATE 1-Obama to meet lawmakers in attempt to protect health law

WASHINGTON, Dec 30 (Reuters) - President Barack Obama plans

to meet Democratic lawmakers in Congress next week to discuss

how to protect his signature healthcare law from Republican

efforts to dismantle it, a White House official said on Friday.

Read more

BRIEF-MiMedx says files lawsuits against two additional former sales employees for breach of contractual obligations

* MiMedx files lawsuits against two additional former sales

employees for breach of contractual obligations

Read more

Ireland confirms bird flu case, carrying out tests

DUBLIN, Dec 30 (Reuters) - Ireland has found the H5N8 bird

flu strain in a wild duck in the south eastern town of Wexford,

the agriculture department said on Friday.

Read more

BRIEF-Jounce Therapeutics files for an IPO of upto $75 mln

* Says applied to list common stock on the Nasdaq Capital

Market under the symbol "JNCE."

Read more

Bulgaria to cull more poultry as bird flu outbreak spreads

SOFIA, Dec 30 (Reuters) - Bulgaria will cull more ducks and

chickens in the southern Plovdiv region and has banned fishing

in lakes and wetlands inhabited by wild migrating birds, the

food safety agency said on Friday, as it struggles to contain a

bird flu outbreak.

Read more

UPDATE 1-Growth hormone deficiency drug from OPKO and Pfizer fails study

Dec 30 (Reuters) - OPKO Health Inc said its

experimental drug for growth hormone deficiency (GHD) in adults

failed to provide a statistically significant benefit over a

placebo in a late-stage study, sending its shares down 14

percent in early trading.

Read more

Bill Gates warns world "vulnerable" to deadly epidemic in next decade

LONDON, Dec 30 (Thomson Reuters Foundation) - Billionaire

philanthropist Bill Gates warned on Friday that the world was

vulnerable to a deadly epidemic of an illness like flu, with the

recent Ebola and Zika outbreaks underlining weaknesses in global

efforts to tackle health crises swiftly.

Read more

BRIEF-Triple-S Management enters into a credit agreement pursuant to which it borrowed approximately $35.5 mln

* Term loan a matures in October 2023 and term loan B and

term loan C mature in January 2024

Read more

Growth hormone deficiency drug from OPKO and Pfizer fails study

Dec 30 (Reuters) - OPKO Health Inc said on Friday

its experimental drug for growth hormone deficiency did not

provide a statistically significant benefit over a placebo in a

late-stage study.

Read more

BRIEF-Beigene announces first patient dosing in China phase I trial with investigational anti-pd-1 monoclonal antibody bgb-a317

* Beigene ltd- dosing of first patient in phase i clinical

trial of bgb-a317 in mainland chinese patients with advanced

solid tumors

Read more

BRIEF-Merck Ltd says received demand notice from NPPA

* says co has been legally advised it has a good defendable

case on merits

Read more

BRIEF-Cachet Pharma to buy stakes in medical instrument firms for 848.1 mln yuan

* Says it plans to buy stakes in 12 medical instrument firms

for a combined 848.1 million yuan ($122.17 million) via share

issue

Read more

BRIEF-Yihua Healthcare plans to issue up to 1 bln yuan bonds

* Says it plans to issue up to 1 billion yuan ($144.07

million) bonds

Read more

Russia reports two outbreaks of bird flu

MOSCOW, Dec 30 (Reuters) - Russia has registered outbreaks

of bird flu on two poultry farms in its southern regions of

Krasnodar and Rostov, the agriculture safety watchdog

Rosselkhoznadzor said in two statements on Friday.

Read more

BRIEF-China Grand Automotive Services unit to sell 70 pct stake in real estate company 88.5 mln yuan to investment company

* Says its subsidiary will sell 70 percent stake in a

Wuxi-based real estate company at 88.5 million yuan to a

Guigang-based investment company

Read more

BRIEF-Golden Meditech to sell its equity interest in China

* Golden Meditech Holdings Ltd - as part of transaction,

golden meditech agrees to give three years' performance

guarantee of ccbc in favour of purchaser

Read more

BRIEF-Traditional Therapy Clinics acquires new property for A$18.46 mln

* New head office building costs RMB92.53 million, which

equates to aud18.46 million at an exchange rate of 5.01

(aud:rmb)

Read more

UPDATE 1-China bird flu has not spread, no impact on poultry market - govt

BEIJING, Dec 30 (Reuters) - China's Ministry of Agriculture

said on Friday the recent outbreaks of bird flu have been

handled in a "timely and effective" manner without spreading and

have not affected chicken products or prices.

Read more

BRIEF-Glycorex Transplantation: New patent granted in USA

* New patent granted in USA

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-C-RAD gets order from German customer of SEK 3 million

* To supply advanced surface tracking solution to German customer

Read more

Thursday, December 29, 2016

UPDATE 1-Elekta says wins order in Stockholm, initially worth SEK 350 mln

* Says Stockholm county council, New Karolinska Solna and

Elekta sign a 13-year collaboration agreement to advance cancer

care

Read more

Swiss stocks - Factors to watch on Friday

ZURICH, Dec 30 (Reuters) - The following are some of the

main factors expected to affect Swiss stocks on Friday.

Read more

BRIEF-Shanghai Dingli Technology Development Group to change name to Pengqi Technology Development

Dec 30 (Reuters) - Shanghai Dingli Technology Development

Group Co Ltd :

Read more

Shanghai confirms new human case of H7N9 bird flu - Xinhua

BEIJING, Dec 30 (Reuters) - Shanghai's health authority has

confirmed a new human case of infection by the H7N9 strain of

avian influenza, the state-owned news agency Xinhua said on

Friday.

Read more

BRIEF-Ilshinbiobase amends contract end date with ISC

* Says it amends contract end date with ISC to Feb. 28, 2017

from Dec. 31

Read more

BRIEF-Guangdong Zhongsheng Pharmaceutical names Chen Yonghong as chairman and general manager

Dec 30 (Reuters) - Guangdong Zhongsheng Pharmaceutical Co.,

Ltd. :

Read more

BRIEF-Lepu Medical Technology Beijing raises 719 mln yuan via private placement

Dec 30 (Reuters) - Lepu Medical Technology Beijing Co Ltd

:



* Says it issued 38,082,627 shares via private placement



* Says it raised about 719 million yuan in total



Source text in Chinese: https://goo.gl/r3aNAa



Further company Coverage:

(Beijing Headline News)



Read more

BRIEF-Legochem Biosciences to raise 5 bln won via rights issue

* Says it will issue 1 million shares via rights issue to

raise 5 billion won, at 5,000 won/share

Read more

BRIEF-PharmAust announces capital raising

Dec 30 (Reuters) - PharmAust Ltd



* Pharmaust raises a further $1.56 mln



*

Source text for Eikon:

Further company coverage:



Read more

Bankers cautious on outlook for global equity deals after 2016 slide

LONDON, Dec 30 (Reuters) - Global equity raising fell by

more than a quarter in 2016, data showed on Friday, hit by

geopolitical shocks and a string of failed initial public

offerings (IPOs), with the outlook for 2017 looking shaky.

Read more

BRIEF-Mast Therapeutics says expects restructuring costs of about $0.4 mln

* Mast Therapeutics Inc - company expects all restructuring

costs relating to workforce reduction to be paid in Q4 of 2016

or Q1 of 2017

Read more

Britain avoids M&A collapse as foreign buyers go Brexit bargain hunting

LONDON, Dec 30 (Reuters) - Britain avoided a collapse in

mergers and acquisitions activity after the shock Brexit vote as

foreign companies used sterling's spectacular devaluation

against the U.S. dollar to snap up British companies, Thomson

Reuters data shows.

Read more

BRIEF-Actinogen Medical seeks trading halt

* requests that its securities be placed into an immediate

trading halt pending an announcement regarding actinogen

medical's application to FDA

Read more

BRIEF-Innocoll receives refusal to file letter from U.S. FDA for xaracoll new drug application

* Innocoll Holdings - FDA indicated xaracoll should be

characterized as drug/device combination, which would require co

submit additional information

Read more

Deals of the day-Mergers and acquisitions

Dec 29 (Reuters) - The following bids, mergers, acquisitions

and disposals were reported by 2100 GMT on Thursday:

Read more

BRIEF-Mylan launches generic Concerta tablets

* Mylan - U.S. launch of methylphenidate hydrochloride

extended-release tablets usp, 18 mg, 27 mg, 36 mg and 54 mg,

generic version of Janssen's Concerta tablets

Source text for Eikon:

Further company coverage:

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BRIEF-Stonepine Capital Management reports 6.4 pct passive stake in Ophthotech Corp

* Stonepine Capital Management Llc - reports 6.4 percent

passive stake in Ophthotech Corp as of Dec 19 - SEC Filing

Source text - http://bit.ly/2hA5aEu

Further company coverage:

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LPC: US syndicated lending flat in 2016 after late-year spurt

NEW YORK, Dec 29 (Reuters) - A fourth-quarter rush of

corporate buyouts and refinancing, as markets rallied on

prospects of looser financial regulations under a Trump

administration, pulled 2016 US syndicated lending volume up to

match the prior year's pace.

Read more

BRIEF-Medivir completes oncology acquisition

* Medivir completes previously announced oncology programs

acquisition

Read more

Fitch Affirms Community Health Systems at 'B'; Outlook Negative

(The following statement was released by the rating agency)

NEW YORK, December 29 (Fitch) Fitch Ratings has removed the

ratings of Community

Health Systems, Inc. (CHS) from Rating Watch Evolving and has

affirmed the

Issuer Default Rating (IDR) at 'B'. The Rating Outlook is

Negative. The ratings

apply to $15.5 billion of debt outstanding at Sept. 30, 2016. A

full list of

rating actions follows at the end of this release.

KEY RATING DRIVERS

Persistent Credit Profile Headwinds: The Negative Out

Read more

BRIEF-Endologix resumes shipments and procedures with AFX

* Endologix resumes shipments and procedures with AFX and

some sizes of AFX2

Source text for Eikon:

Further company coverage:

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BRIEF-Lerado Financial Group Co updates on formation of a joint venture securities company

* Registered capital of jv company is expected to be rmb2

billion

Read more

UPDATE 3-FDA rejects Cempra's antibiotic for pneumonia, shares sink

* Shares nearly halve in premarket trading

(Adds analyst comment)

Read more

BRIEF-Skyline Medical receives requested extension from NASDAQ panel

* Skyline Medical - NASDAQ hearings panel has granted

company's request for continued listing on NASDAQ pursuant to an

extension through April 11, 2017

Read more

BRIEF-Mylan NV launches generic Cerebyx injection

* Mylan NV says U.S. launch of fosphenytoin sodium injection

USP

Source text for Eikon:

Further company coverage:

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BRIEF-Nuvasive to resume XLIF procedures in Japan in first quarter 2017

* Nuvasive to resume XLIF procedures in Japan in first

quarter 2017

Read more

BRIEF-Yunnan Baiyao's share trade to resume on Dec 30

* Says share trade to resume on December 30 after

controlling shareholder has received 25.4 billion yuan ($3.65

billion)investment from Newhuadu Industrial Group

Read more

BRIEF-Sun Pharmaceutical Industries says fire broke out at Ahmednagar factory

* Sun Pharmaceutical Industries Ltd clarifies on news item

"blast at Sun Pharma unit"

Read more

BRIEF-Boryung Pharm signs 82.97 bln won contract with Rampharma

* Says it signs 82.97 billion won contract with Rampharma to

provide medicine

Read more

BRIEF-Crown Bioscience International unit to set up unit in U.S and new unit to form strategic cooperation with New Iberia Research Center

* Says its subsidiary Crown Bioscience Inc. plans to set up

a sub-subsidiary named Crown Bioscience Louisiana. in U.S

Read more

BRIEF-Lupin gets tentative approval for generic Giazo tablets

* Lupin Ltd says lupin receives tentative approval for

generic giazo tablets

Read more

Wednesday, December 28, 2016

Swiss stocks - Factors to watch on Dec 29

ZURICH, Dec 29 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.2 percent lower at 8,237 points on Thursday,

according to premarket indications by bank Julius Baer

.

Read more

BRIEF-Jiangsu Lianhuan Pharmaceutical appoints Wu Wenge as general manager

Source text in Chinese: https://goo.gl/O0xpXY;

https://goo.gl/POSw2Z

Read more

BRIEF-Argenx publishes seminal data supporting therapeutic potential of ARGX-110

* Argenx announces publication of seminal data supporting the therapeutic potential of

ARGX-110 for acute myeloid leukemia in the Journal of Experimental Medicine

Read more

BRIEF-Lionco Pharmaceutical Group receives government subsidy of 21.3 mln yuan

* Says it received government subsidy of 21.3 million yuan

to support its R&D of medicine

Read more

BRIEF-Jilin Gpro Titanium Industry completes dissolution of finance lease unit

* Says it completes dissolution of Nanjing-based finance

lease unit on Dec. 27

Read more

BRIEF-Zhejiang Jiuzhou Pharmaceutical appoints Hua Lirong as chairman, Chen Zhihong as general manager

* Says Hua Dexuan resigned from chairman of the board, Hua

Lirong resigned from general manager

Read more

UPDATE 2-U.S. FTC requires divestitures in $13.53 bln Boehringer-Sanofi deal

WASHINGTON, Dec 28 (Reuters) - German pharmaceutical company

Boehringer Ingelheim agreed to divest five types of animal

health products to settle charges that a proposed asset swap

with Sanofi would harm competition, the U.S. Federal Trade

Commission said on Wednesday.

Read more

Through reclusive Wa, China's reach extends into Suu Kyi's Myanmar

* Making peace with ethnic armed groups is Suu Kyi's

priority

Read more

BRIEF-Beijing Beilu Pharmaceutical receives GMP certificate

* Says it received goods manufacture practice (GMP)

certificate from State Food and Drug Administration of Beijing

Read more

BRIEF-Alere provides update on Arriva Medical

* Arriva has filed an appeal with administrative law judge

(ALJ) at CMS seeking to reinstate Arriva's billing status

Read more

BRIEF-Provectus Biopharmaceuticals terminates Peter Culpepper as interim CEO and COO

* Provectus Biopharmaceuticals terminates Peter Culpepper as

interim CEO and COO

Source text for Eikon:

Further company coverage:

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UPDATE 2-Burger King, Tim Hortons to curb antibiotics used in chicken

CHICAGO/LOS ANGELES, Dec 28 (Reuters) - Restaurant chains

Burger King and Tim Hortons plan to switch to chicken raised

without antibiotics considered "critically important" to human

medicine, their owner said on Wednesday, making it the latest

company to ditch the drugs over health concerns.

Read more

BRIEF-Regeneus announces collaboration with AGC Asahi Glass

* Regeneus collaborates with agc asahi for exclusive

manufacture of progenza stem cell technology for Japanese market

Read more

BRIEF-Neurometrix announces $7 mln private placement of preferred stock and warrants

* Neurometrix announces $7.0 million private placement of

preferred stock and warrants

Read more

Deals of the day-Mergers and acquisitions

Dec 28 (Reuters) - The following bids, mergers, acquisitions

and disposals were reported by 2100 GMT on Wednesday:

Read more

REUTERS AMERICA NEWS PLAN FOR WEDNESDAY DEC 28

For latest stories search by Slug or Headline Keyword in

your CMS or Advanced Search in Media Express.

Read more

U.S. FTC requires divestitures in $13.53 bln Boehringer-Sanofi deal

WASHINGTON, Dec 28 (Reuters) - The U.S. Federal Trade

Commission said on Wednesday that German pharmaceutical company

Boehringer Ingelheim agreed to divest five types of animal

health products to settle FTC charges that a proposed asset swap

with Sanofi would harm competition.

Read more

BRIEF-Bioporto expands its NGAL related patent portfolio

* Has entered into exclusive license agreement with Trustees of Columbia, University for

NGAL patents

Read more

BRIEF-Myriad Genetics says entered into credit agreement for $300 mln on Dec.23-SEC filing

* On Dec. 23, 2016, entered into a credit agreement - SEC

filing

Read more

BRIEF-Immunocellular Therapeutics Ltd files for offering of up to $20 mln of common units

* Immunocellular Therapeutics Ltd - files for offering of up

to up to $20.0 million of common units, each consisting of share

of common stock, and warrant

Source text http://bit.ly/2iqqMjC

Further company coverage:

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BRIEF-Cadila Healthcare unit Zydus buys six brands from MSD

* Six brands acquired are Deca-Durabolin, Durabolin,

Sustanon, Multiload, Sicastat and Axeten

Read more

BRIEF-Blirt buys device for 629,000 zlotys to produce proteins

* Buys device and software for pilot production of proteins for 629,000 zlotys ($148,696)

gross

Read more

BRIEF-Ascendance Biotechnology licenses the right to manufacture and sell cytiva cardiomyocytes

* Ascendance biotechnology licenses the right to

manufacture, market and sell cytiva cardiomyocytes

Read more

BRIEF-Concordia International says Beighton will retire from co's international segment president role

* Concordia International - effective january 1, 2017, john

beighton will retire from his current role as president of

company's international segment

Read more

BRIEF-Guangxi Wuzhou Zhongheng, unit plan to set up investment firm

* Says it and unit plan to invest 400 million yuan ($57.50

million) to set up investment firm

Read more

BRIEF-Jiangsu Lianhuan Pharma's chairman, general manager retire

* Says chairman Yao Xingtian, general manager Qian Ni resign

as they have reached retirement age

Read more

BRIEF-Chongqing Sanxia Paints sold shares in Beijing Beilu Pharma for 182.3 mln yuan

* Says it has sold 10 million shares in Beijing Beilu Pharma

for 182.3 million yuan ($26.21 million) on Dec 28

via block trade

Read more

BRIEF-Zhuhai Hokai Medical Instruments signs hospital construction contract

* Says it signs hospital construction contract with

investment of 250 million yuan ($35.94 million)

Read more

BRIEF-1nkemia invests 100,000 euros in Arkyne Technologies

* Its unit IUCT Empren s.l. has invested 100,000 euros in the clean-tech company Arkyne

Technologies s.l. , reaching a stake of 4 percent

Read more

UPDATE 1-Now China's Wuxi to suspend poultry trade amid bird flu fears

BEIJING, Dec 28 (Reuters) - The eastern Chinese city of Wuxi

will suspend poultry trade from Thursday amid fears about bird

flu, becoming the second city in Jiangsu province to halt live

poultry markets, it said.

Read more

Tuesday, December 27, 2016

China's Wuxi city to suspends poultry trade on avian flu concerns

BEIJING, Dec 28 (Reuters) - Wuxi city in China's eastern

Jiangsu province will suspend poultry trading starting from Dec.

29 amid avian flu concerns, the city's information office

announced on Wednesday on its official microblog.

Read more

BRIEF-Wonik to buy stake in agriculture unit for 659.4 mln won

* Says it will buy 65,935 shares of its subsidiary, an

agriculture firm, for 659.4 million won

Read more

BRIEF-Ose immunotherapeutics signs license agreement with Servier

* Grants Servier license option on exclusive worldwide

rights for development and commercialization of Effi-7

Read more

BRIEF-UMN Pharma announces exercise of options

* Says 200,000 units of its 20th series options were

exercised to 200,000 shares of its common stock on Dec. 28

Read more

BRIEF-Zhejiang Nhu's controlling shareholder gets exchange's approval for exchangeable bonds issue

* Says its controlling shareholder gets Shenzhen Stock

Exchange's approval to issue up to 2.0 billion yuan ($287.60

million) exchangeable bonds

Read more

BRIEF-Tibet Rhodiola Pharmaceutical Holding receives industrial development support funds of 17.4 mln yuan

* Says it received industrial development support funds of

17.4 million yuan from Finance Bureau of Shannan

Read more

BRIEF-Che Hongli cuts stake in Sinocare to 28.7 pct from 33.7 pct

* Says the shareholder Che Hongli cut stake in Sinocare to

28.7 percent from 33.7 percent

Read more

BRIEF-Hybio Pharmaceutical's METHOD FOR SOLID PHASE SYNTHESIS OF LIRAGLUTIDE gets patent in EU

* Says the co's METHOD FOR SOLID PHASE SYNTHESIS OF

LIRAGLUTIDE received patent in Europe

Read more

BRIEF-Apiam Animal Health acquires AllStock (NSW) Pty

* consideration for acquisition is a combination of 70% cash

and 30% scrip.

Read more

BRIEF-Nanjing Hicin Pharmaceutical issues prospectus for Shenzhen IPO

Source text in Chinese: http://bit.ly/2iBOTPo

(Reporting by Hong Kong newsroom)

Read more

INSIGHT-Serial testers and cursory checks: India's flawed generic drug trials business

HYDERABAD, Dec 28 (Reuters) - Vasudeva Prakash left his job

as a mechanic in Hyderabad three years ago for what he calls a

more lucrative career: taking part in clinical trials on generic

drugs.

Read more

BRIEF-Regeneus Ltd seeks trading halt

* Seeks trading halt to enable co to complete signing of

transaction documents regarding entry into strategic

collaboration and licensing agreement for Progenza Stem Cell

Technology in Japan

Source text for Eikon:

Further company coverage:

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BRIEF-Seattle Genetics says entered tenth amendment to development and supply agreement with Abbvie Inc

* Seattle Genetics - amendment extends term of supply

agreement from August 22, 2021 through and including December

31, 2025

Read more

BRIEF-Neogenomics Inc, some units and Neogenomics Laboratories enter credit agreement - SEC filing

* Neogenomics Inc - on December 22, 2016, Neogenomics

Laboratories Inc and co and units entered into a credit

agreement - SEC filing

Read more

BRIEF-Sucampo Pharmaceuticals say issued $300 mln of convertible senior notes due 2021 - SEC filing

* Sucampo Pharmaceuticals Inc - notes were issued to Leerink

Partners LLC

Read more

BRIEF-Neogen says acquired Brazil-based Rogama Industria e Comercio Ltda

* Neogen - on December 27, 2016, Neogen Corporation annouced

that it has acquired Brazil-based Rogama Industria e Comercio

Ltda

Read more

BRIEF-Capnia to pay Essentialis $750,000 if merger is terminated - SEC filing

* Capnia - under merger agreement co to pay Essentialis

termination fee of $750,000 under specified circumstances - SEC

filing

Read more

BRIEF-The ensign group purchases fifteen wisconsin assisted living assets

* The ensign group purchases fifteen wisconsin assisted

living assets

Read more

Abbott gets U.S. antitrust approval to buy St. Jude Medical

WASHINGTON, Dec 27 (Reuters) - Healthcare company Abbott

Laboratories has won U.S. antitrust approval for its

proposed purchase of medical device maker St. Jude Medical Inc

, the Federal Trade Commission said on Tuesday.

Read more

UPDATE 1-Abbott gets U.S. antitrust approval to buy St. Jude Medical

WASHINGTON, Dec 27 (Reuters) - Healthcare company Abbott

Laboratories has won U.S. antitrust approval for its

proposed purchase of medical device maker St. Jude Medical Inc

, the U.S. Federal Trade Commission said on Tuesday.

Read more

US STOCKS-Industrials keep Dow away from 20,000

* Indexes up: Dow 0.1 pct, S&P 0.26 pct, Nasdaq 0.54 pct

(Updates to early afternoon)

Read more

U.S. posts rules for addressing cyber bugs in medical devices

Dec 27 (Reuters) - The U.S. government on Tuesday issued

rules for addressing cyber vulnerabilities in medical devices,

providing manufacturers with guidelines for fixing security bugs

in equipment, including pacemakers, insulin pumps and imaging

systems.

Read more

BRIEF-Amoeba's BIOMEBA registration for marketing on US territory is deferred

* Announces that BIOMEBA registration needed for marketing on US territory is deferred

Read more

Fitch: Hypermarcas' Asset Sale is Credit Positive

(The following statement was released by the rating agency)

SAO PAULO, December 27 (Fitch) Hypermarcas' sale of its

Disposable Products

Business to Ontex Group NV (Ontex) is considered credit positive

by Fitch

Ratings, as it strengthens the company's already deleveraged

capital structure.

Depending on the use of proceeds, this transaction could

strengthen Hypermarcas'

ability to generate more robust cash flows from operations

(CFFO) and free cash

flows (FCF), which continue to be key credit

Read more

Sanofi sues Novo Nordisk over diabetes drugs in the U.S.

PARIS/NEW YORK, Dec 27 (Reuters) - France's Sanofi

has filed a lawsuit in the United States accusing Novo Nordisk

of falsely claiming that Sanofi insulin drugs would

no longer be available for many U.S. patients so it could

promote its competing drug.

Read more

BRIEF-Scor receives authorization to open a composite branch office in India

* Scor receives the authorization to open a composite branch office in India

Read more

BRIEF-Perceptive Advisors buys 85,275 shares of Amicus Therapeutics on Dec 23

* Perceptive Advisors LLC reports purchase of 85,275 shares

of Amicus Therapeutics Inc's common stock on Dec 23 -

SEC filing

Read more

US STOCKS-Dow nears 20,000, Nasdaq hits record as tech stocks rise

* Indexes up: Dow 0.17 pct, S&P 0.34 pct, Nasdaq 0.71 pct

(Adds details, comments, updates prices)

Read more

BRIEF-Capnia and Essentialis announce merger to create rare disease Therapeutics company

* Capnia and essentialis announce merger to create rare

disease therapeutics company

Read more

BRIEF-Pernix Therapeutics ceases discussions on possible restructuring of capital structure

* On Dec 26, 2016, co ceased discussions with noteholders on

possible consensual restructuring of co's capital structure

Read more

UPDATE 1-Seattle Genetics' cancer drug put on clinical hold after 4 deaths

Dec 27 (Reuters) - Seattle Genetics Inc said four

people had died in trials testing its experimental cancer drug,

prompting the U.S. Food and Drug Administration to impose a

clinical hold on several early-stage studies.

Read more

BRIEF-Neogen acquires Brazil-based Rogama

* Neogen Corp - terms of current agreement were not

disclosed.

Read more

BRIEF-Mimedx announces preliminary investigation findings

* Mimedx Group Inc- company does not anticipate any material

effect on company's financial statements resulting from

investigation findings

Read more

BRIEF-Intelgenx announces agreement with endo ventures

* Intelgenx announces development and commercialization

agreement with endo ventures

Source text for Eikon:

Further company coverage:

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Hong Kong's first bird flu patient this winter dies

HONG KONG, Dec 27 (Reuters) - An elderly Hong Kong man died

on Christmas Day from bird flu, the government said on Tuesday,

the first human infection in the city this winter.

Read more

BRIEF-Sichuan Languang's unit wins land auctions for about 1 bln yuan in Xi'an

* Says unit wins land auctions for about 1.02 billion yuan

($146.78 million) in Xi'an

Read more

BRIEF-Handa Pharmaceuticals announces IPO of 104.4 mln shares

* Says initial public offering of 104.4 million common

shares with par value of T$10 per share

Read more

BRIEF-Alba says over 40 percent of Clinica Baviera shareholding entered sale talks

* Says shareholders that add to over 40 percent of Clinica

Baviera shareholding entered talks for the sale of

shares package

Read more

BRIEF-Clinica Baviera says Eduardo Baviera, Julio Baviera are not currently involved in sale talks

* Says Eduardo Baviera and Julio Baviera are not currently

involved in sale talks initiated by Alba and other

shareholders

Read more

BRIEF-Suning Universal's unit signs strategic agreement with Syneron Medical

* Says health unit signs strategic agreement with Syneron

Medical Ltd

Read more

BRIEF-Universal Vision Biotechnology signs memorandum to use 45 mln yuan to set up JV

* Says it signed a memorandum with a Hangzhou-based holding

company and a Shanghai-based IT company to use 45 million yuan

to set up a JV

Read more

BRIEF-Nacimbio, Pharmstandard, Kedrion Biopharma sign memorandum

* Says with Pharmstandard signs memorandum with

Kedrion Biopharma (Italy) aimed at joint implementation of

projects for production of products from blood plasma

Source text: http://bit.ly/2icy9Oc

Read more

BRIEF-JVM receives patent

* Says it receives patent on Dec. 27, for Automatic

Medication control method

Read more

BRIEF-Spain's Clinica Baviera share trading suspended - regulator

* Says trading in Spain's Clinica Baviera SA has

been suspended Source text for Eikon: [http://bit.ly/2hJhu1c

]

Further company coverage:

(Reporting by Madrid Newsroom)

Read more

Monday, December 26, 2016

Indian state orders poultry cull after bird flu outbreak

BHUBANESWAR, India, Dec 27 (Reuters) - An eastern Indian

state ordered the cull of more than 2,500 chickens and other

poultry after four dead crows and three dead poultry tested

positive for the highly pathogenic H5N1 virus, officials said on

Tuesday.

Read more

Swiss stocks - Factors to watch on Dec 26

ZURICH, Dec 27 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.1 percent higher at 8,241 points on Tuesday,

according to premarket indications by bank Julius Baer

.

Read more

FEATURE-Gay rights groups brave abuse, violence to fight HIV in Cameroon

YAOUNDE, Dec 27 (Thomson Reuters Foundation) - Sitting in a

circle with several other young men in a charity's offices in

Cameroon's capital, Fleur listens intently to the speaker talk

about gay sex before slowly raising his hand.

Read more

PRESS DIGEST- New York Times business news - Dec 27

Dec 27 (Reuters) - The following are the top stories on the

New York Times business pages. Reuters has not verified these

stories and does not vouch for their accuracy.

Read more

BRIEF-Sinocare's controlling shareholder unloads stake in the company

* Says controlling shareholder has sold 1.6 percent stake in

the company on Dec 13 Dec 26

Read more

BRIEF-Corestem receives patent

* Says it receives patent about compositions for improving

migration potential of stem cells

Read more

BRIEF-Glenmark Pharmaceuticals receives ANDA approval for cancer drug

* Says Glenmark Pharmaceuticals receives ANDA approval for

Tretinoin capsules, 10 mg

Source text: http://bit.ly/2ilDvUs

Further company coverage:

Read more

BRIEF-Jilin Gpro Titanium Industry to issue bonds, boost unit's capital

* Says it plans to issue up to 700 million yuan ($100.75

million) bonds

Read more

BRIEF-Zhejiang Yongtai Technology cuts 4.5 pct stake in Jiangxi Fushine Pharmaceutical

* Says the co cut 4.5 percent stake in Jiangxi Fushine

Pharmaceutical Co Ltd, down to 13.3 percent

Read more

RPT-INSIGHT-Beijing buyers club? China's cancer patients gamble on grey market

* Two-thirds of patients tracked by Reuters bought on grey

mkt

Read more

BRIEF-Jubilant Life Sciences gets members' nod for NCD issue

* Gets members' nod for NCD issue

Source text: http://bit.ly/2ijs4gm

Further company coverage:

Read more

BRIEF-Ningbo Medicalsystem Biotechnology to set up medical institute unit in Fuzhou

Dec 26 (Reuters) - Ningbo Medicalsystem Biotechnology Co Ltd

:

Read more

BRIEF-Shanghai Shenqi Pharmaceutical Investment Management says investment firm sells 5 pct stake in the co

Dec 26 (Reuters) - Shanghai Shenqi Pharmaceutical Investment

Management Co Ltd :

Read more

Sunday, December 25, 2016

UPDATE 1-China's Suzhou city to halt live poultry trade over bird flu concerns

BEIJING, Dec 25 (Reuters) - A Chinese city said on Sunday it

will suspend the trade of live poultry in the interests of

public health after neighbouring provinces reported cases of

human bird flu infections.

Read more

REFILE-China's Suzhou city to halt live poultry trade on bird flu concerns

BEIJING, Dec 25 (Reuters) - A Chinese city said on Sunday it

will suspend trade of live poultry in the interests of public

health after neighbouring provinces reported cases of human bird

flu infections.

Read more

Saturday, December 24, 2016

UPDATE 1-Status Quo guitarist Rick Parfitt dies aged 68

LONDON, Dec 24 (Reuters) - Rick Parfitt, the guitarist of

British rock group Status Quo, died in hospital on Saturday in

Spain aged 68 after suffering from a severe infection.

Read more

Status Quo guitarist Rick Parfitt dies aged 68

LONDON, Dec 24 (Reuters) - Status Quo guitarist Rick Parfitt

died in hospital on Saturday in Spain aged 68 after suffering

from a severe infection, his manager said.

Read more

China uncovers 500,000 food safety violations in nine months

SHANGHAI, Dec 24 (Reuters) - China, rocked in recent years

by a series of food safety scandals, uncovered as many as half a

million illegal food safety violations in the first three

quarters of the year, an official said.

Read more

Friday, December 23, 2016

BRIEF-Mylan unit enters into amendment and waiver agreement to loan agreement dated as of September 17, 2014

* On dec 22, unit of Co entered into amendment and waiver

agreement to loan agreement dated as of September 17, 2014 - SEC

filing

Read more

BRIEF-Celsion files for offering of up to $15 mln in shares of common stock and base warrants

* Files for offering of up to $15 million in shares of

common stock and base warrants - SEC filing

Read more

BRIEF-Lion Biotech files for mixed shelf of up to $100 mln

* Lion Biotechnologies Inc - files for mixed shelf of up to

$100 million - SEC filing

Source text: (http://bit.ly/2hRk48l)

Further company coverage:

Read more

BRIEF-Aina Le'a Inc- no termination fees regarding termination of merger agreement with Origo Acquisition Corporation

* Aina Le'a Inc- there are no termination fees in connection

with termination of merger agreement with Origo Acquisition

Corporation

Source text: (http://bit.ly/2hRj3x2)

Further company coverage:

Read more

FDA approves Biogen drug for lead genetic cause of infant death

Dec 23 (Reuters) - The U.S. Food and Drug Administration on

Friday said it has approved Biogen Inc's drug to treat

spinal muscular atrophy, the leading genetic cause of death in

infants.

Read more

Migraine drugs may repeat rheumatoid arthritis success

Dec 23 (Reuters) - Nearly two decades ago, several drugs to

treat rheumatoid arthritis hit the shelves in rapid succession,

opening up a huge market for the treatment of the autoimmune

joint disorder.

Read more

BRIEF-Portola Pharmaceuticals says FDA accepts NDA for priority review for betrixaban

* Portola Pharmaceuticals announces FDA accepts New Drug

Application for priority review and EMA validates marketing

authorization application for oral, Factor Xa inhibitor

anticoagulant betrixaban

Read more

BRIEF-Neovasc announces update in litigation with Cardiaq

* Will deposit US$70 million into a joint escrow account and

enter into a general security agreement related to remaining

damages awarded by court

Read more

BRIEF-Align Technology enters agreement to buy four parcels of real estate

* On Dec. 19 co,LBA RIV-COMPANY entered into a purchase and

sale agreement for purchase by company of four parcels of real

estate

Read more

UPDATE 3-Cardinal settles with U.S. over suspicious painkiller shipments

NEW YORK, Dec 23 (Reuters) - Cardinal Health Inc

said on Friday it has agreed to pay $44 million to resolve

claims it failed to alert the U.S. Drug Enforcement

Administration (DEA) to suspiciously large orders of addictive

painkillers.

Read more

BRIEF-Oncobiologics issues $8.35 mln senior secured notes, warrants

* Used a portion of proceeds from sale of notes to pay off

its existing senior secured bank loans

Read more

Deals of the day-Mergers and acquisitions

Dec 23 (Reuters) - The following bids, mergers, acquisitions

and disposals were reported by 1445 GMT on Friday:

Read more

BRIEF-EnteroMedics announces 1-for-70 reverse stock split

* Declared a 1-for-70 reverse stock split of co's common

stock, will be effective for trading purposes upon commencement

of trading on Dec 28

Read more

BRIEF-Helix Biopharma successfully out-licenses late stage Biphasix technology

* Under terms of agreement, Xisle has paid an up-front fee

and agreed to subsequent milestone payments

Read more

BRIEF-Helius Medical Technologies files for mixed shelf of up to $100 mln - SEC filing

* May use a portion of net proceeds to invest,acquire

businesses,technologies we believe are complementary

Source text: (http://bit.ly/2i1SNQX)

Further company coverage:

Read more

BRIEF-C R Bard's board amends company's By-Laws to implement proxy access

* On Dec 22 board amended co's by-laws to implement proxy

access-SEC filing

Source text: [http://bit.ly/2h8H2np]

Further company coverage:

Read more

BRIEF-B-Soft's general manager to buy more shares, shareholder Youngor to sell shares

* Says its general manager plans to buy shares in the

company worth at least 400 million yuan ($57.57 million) from

Dec 26 to June 25, 2017

Read more

BRIEF-Ningbo MedicalSystem Biotechnology terminates investment plan, stake acquisition

Further company coverage:

(Reporting by Hong Kong newsroom)

Read more

BRIEF-DSMB positively assesses Mabion's comparative study of MabionCD20 drug

* Said on Thursday that Data and Safety Monitoring Board

(DSMB) assessed clinical data and safety data obtained from

patients in comparative study of the drug MabionCD20 and the

MabThera reference product (MabThera)

Read more

BRIEF-Autobio Diagnostics to buy Hong Kong Bio-star's automated bio-analyzer business

* Says it plans to buy Hong Kong Bio-star Technology

Development's automated bio-analyzer business for 169.5 million

yuan ($24.40 million)

Read more

BRIEF-Shanghai Modern Pharmaceutical to invest 98 mln yuan in pharmaceutical unit

* Says it will invest 98 million yuan in a Wuhan-based

pharmaceutical subsidiary, raising stake in the subsidiary to

96.2 percent from 93.2 percent

Read more

UPDATE 2-China reports first two human fatalities from bird flu this winter

BEIJING, Dec 23 (Reuters) - Two people in China's Anhui

province have died from H7N9 bird flu, the first fatalities in

China among this winter's cases, while Macau reported its first

human H7N9 infection since the former Portuguese colony returned

to China in 1999.

Read more

BRIEF-Vectura signs deal with Mundipharma on respiratory treatments

* Global development programme with Mundipharma for PMDI

inhaled triple therapy (VR2076) for asthma and COPD

Read more

BRIEF-Celon Pharma and Polfarmex grant license for product distribution in France

* Celon Pharma and Polfarmex SA grant 5-year registration

dossier and distribution right license on solution for dry

powder inhaler in France

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

Thursday, December 22, 2016

German stocks - Factors to watch on December 23

FRANKFURT, Dec 23 (Reuters) - The following are some of the

factors that may move German stocks on Friday:

Read more

BRIEF-Alkem Labs says US FDA closed inspection at co's Daman unit

* Says closure of US FDA inspection at Alkem's Daman

facility

Source text: http://bit.ly/2hOpaCs

Further company coverage:

Read more

China to relax foreign investment rules for aged care - State Council

BEIJING, Dec 23 (Reuters) - China is set to relax

regulations for foreign elderly care firms in an effort to

attract investment, the State Council said in a statement issued

on Friday.

Read more

Singapore Nov factory output expands at fastest pace in over 2-1/2 years

SINGAPORE, Dec 23 (Reuters) - Singapore's industrial

production in November expanded at its fastest annual pace since

March 2014, buoyed by strong electronics and pharmaceuticals

output, data showed on Friday.

Read more

BRIEF-Alteogen receives patent

* Says it received Japan patent on Dec. 21, for modified

antibody in which motif comprising cysteine residue is bound,

modified antibody-drug conjugate comprising the modified

antibody, and production

Read more

BRIEF-EyeGene receives patent

* Says it received Japan patent on Dec. 21, for vaccine for

inducing an improved immune reaction

Read more

BRIEF-Admedus on track to achieve forecast $21m in annual revenue

* Anticipates finishing year with sales considerably

stronger than previous year

Read more

REFILE- Belgium's Ontex to acquire Hypermarcas personal hygiene business

Dec 22 (Reuters) - Belgium's Ontex Group NV said

it has entered into an agreement to acquire the personal hygiene

business of Brazil's Hypermarcas SA for an enterprise

value of 1 billion reais ($304.28 million).

Read more

Many Brazilian women avoiding pregnancy due to Zika fears - study

LONDON, Dec 23 (Reuters) - Brazil should urgently review its

reproductive health policies, scientists said on Friday, to

support the more than 50 percent of potential mothers who say

they want to avoid pregnancy due to fears about the Zika virus.

Read more

BRIEF-Ontex agrees to buy personal hygiene business of Hypermarcas

* Ontex announces agreement to acquire the personal hygiene

business of Hypermarcas

Read more

BRIEF-TSO3 says secured access to automated receivables factoring program

* TSO3 Inc says may factor its getinge receivables at any

time

Read more

Guinea trial shows "historic" success for Ebola vaccine

LONDON, Dec 23 (Reuters) - A vaccine developed by Merck

is the first shown to be highly effective in preventing

human infection with Ebola, according to final results from a

clinical trial.

Read more

BRIEF-Galena Biopharma and its former ceo reached agreement to proposed settlement to resolve an investigation by SEC

* Galena Biopharma -on December 22, co and its former ceo

reached agreement in principle to proposed settlement that would

resolve an investigation by SEC

Read more

BRIEF-Alcon receives U.S. FDA approval for acrysof iq restor +3.0d multifocal toric intraocular lens

* Alcon - U.S. commercialization expected to start on a

rolling basis in Q1 of 2017 for acrysof iq restor

Read more

BRIEF-BPH energy looks to raise about $1.8 mln via rights placement

* Announces a pro rata non-renounceable rights to raise up

to approximately $1.8 million

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Isentric announces intention to raise about $2 mln

* Company intends to raise up to approximately $2 million

before costs, through issue of up to 33.9 million new shares

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Cytrx Corp says files for mixed shelf offering of up to $200 mln- SEC filing

* Cytrx Corp says files for mixed shelf offering of up to

$200 million - SEC filing

Source text: (http://bit.ly/2hdZRJ7)

Further company coverage:

Read more

BRIEF-Icad says entered into asset purchase agreement with Invivo Corp- SEC filing

* Icad - On Dec 16, 2016, co entered into an asset purchase

agreement between company and Invivo Corporation - SEC filing

Read more

BRIEF-Poxel announces departure of its CFO Eric Massou

* New chief financial officer will be announced in Q1 of 2017

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Vifor Pharma & Chemocentryx expands alliance to include CCX140 to treat renal diseases

* Vifor Pharma and Chemocentryx announce expansion of kidney

health alliance to include CCX140 to treat renal diseases

Read more

Teva agrees to pay more than $519 mln to settle bribe allegations - DoJ

WASHINGTON, Dec 22 (Reuters) - Teva Pharmaceutical

Industries agreed to pay more than $519 million to

settle criminal and civil allegations that the company paid

bribes to officials in Mexico, Ukraine and Russia to bolster

sales of its pharmaceutical products, the U.S. Justice

Department said in a press release Thursday.

(Reporting by Joel Schectman; Editing by Chizu Nomiyama)

Read more

BRIEF-BrainCool takes up loan of SEK 10 mln

* Takes up loan of 10 million Swedish crowns ($1.09 million)

for preparations for launch in US and financing of acquisition

of BeneChill

Read more

Teva to pay US government $519 mln over foreign bribery charges

Dec 22 (Reuters) - Israel's Teva Pharmaceutical Industries

Ltd , said on Thursday it had agreed to pay

$519 million to resolve charges related to the U.S. Foreign

Corrupt Practices Act.

Read more

BRIEF-Xintela reports positive results from completed horse study

* Says completed horse study met its primary endpoint,

demonstrating that Xintela's stem cells are safe

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Bioanalytical Systems Q4 loss per share $0.25

* Bioanalytical Systems - management to seek alternatives to

enable co to repay indebtedness to Huntington bank in full upon

expiration of forbearance period

Read more

BRIEF-PerkinElmer says Varian required to pay fee of up to $22.08 mln if deal is terminated

* PerkinElmer - Under circumstances, upon termination of

deal with varian,purchaser will be required to pay company a

termination fee of up to $22.08 million

Source text: (http://bit.ly/2hYKrtq)

Further company coverage:

Read more

BRIEF-Aurinia announces $25 million bought deal financing

* Aurinia Pharmaceuticals Inc - Underwriters have agreed to

purchase 11.1 million units from company at price of us$2.25 per

unit

Read more

BRIEF-Xoma Corp says entered into two royalty interest acquisition agreements with Healthcare Royalty Partners II

* Xoma corp - under first acquisition agreement,co, unit

sold rights for license dated aug 18,2005 for a payment of $6.5

million upfront

Read more

BRIEF-Celgene says oral OTEZLA receives positive nice recommendation for adults with psoriatic arthritis

* Says Otezla will be used for treatment of patients with

active psoriatic arthritis

Read more

BRIEF-MedFirst Healthcare Services to issue 1st series unsecured convertible corporate bonds of T$300 mln

* Says it will issue the 1st series unsecured convertible

corporate bonds, worth T$300 million

Read more

New Japan bird flu outbreak brings fresh cull of chickens as Asia spread fears grow



Read more

UPDATE 1-Watchmaker Swatch goes into car batteries as investors question strategy

* Investors question Swatch Group strategy in shrinking

market

Read more

BRIEF-Mercator Medical unit signs deal for gloves factory development

* Said on Wednesday that its Thailand-based unit Mercator

Medical (Thailand) Ltd. signed a deal with Thailand-based JWS

Construction Co. Ltd. for development of gloves factory

Read more

BRIEF-China Resources Double-crane Pharmaceutical to take out loan of up to 800 mln yuan

Dec 22 (Reuters) - China Resources Double-crane

Pharmaceutical :

Read more

Wednesday, December 21, 2016

Actelion battle heats up, Monte Paschi in focus. For more see the European equities LiveMarkets blog

LONDON, Dec 22 (Reuters) - Live coverage of European markets now available

on cpurl://apps.cp./cms/?pageId=livemarkets

Read more

French and Benelux stocks-Factors to watch on Dec. 22

PARIS, Dec 22 (Reuters) - Below are company-related news and

stories from French and Benelux media which could have an impact

on the region's markets or individual stocks.

Read more

BRIEF-Soiken Holdings unit to set up cosmetic JV

* Says its unit to set up cosmetic JV in Tokyo with a

Japan-based firm on Dec. 26

Read more

BRIEF-Tsumara & Co to set up unit for management of Tsumara group companies in China

* Says it plans to set up a wholly owned subsidiary with

capital of 300 million yuan in Shanghai

Read more

BRIEF-MedFirst Healthcare Services to issue new shares for operating funds enrichment

* Says it will issue 3 million new shares of its common

stock with par value of T$10 per share for operating funds

enrichment

Read more

BRIEF-Sun Pharma Advanced Research gets complete response letter from FDA for Xelpros

* Says CRL references recent FDA inspection at Sun Pharma

Industries' halol unit

Read more

BRIEF-Access Bio receives patent

* Says it receives patent about single-pad strip for an

improved lateral flow assay and a test device

Read more

BRIEF-Rayence says annual cash dividend for 2016

* Says it will pay annual cash dividend at 300 won/share for

2016

Read more

UPDATE 1-Brazil's Hypermarcas to sell diaper unit to Ontex, source says

SAO PAULO, Dec 22 (Reuters) - Hypermarcas SA,

Brazil's most diversified pharmaceutical firm, has agreed to

sell a diaper business to Belgium's Ontex Group NV

for about 1 billion reais ($300 million) in cash, a person with

knowledge of the transaction said on Wednesday.

Read more

Shanghai says treating man diagnosed with bird flu

BEIJING, Dec 22 (Reuters) - Shanghai's health authority has

confirmed it is treating a man diagnosed with H7N9 bird flu, the

third case of human infection in China this week.

Read more

BRIEF-Benitec biopharma signs new research and collaboration agreement

* New research and collaboration agreement has been signed

with royal holloway university of london

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Oxford Immunotec Global files for a mixed shelf of up to $150 mln

* Oxford Immunotec Global Plc - files for a mixed shelf of

up to $150 million - SEC filing

Source text - http://bit.ly/2hWGDZO

Further company coverage:

Read more

BRIEF-Kleopatra Holdings 1 SCA files for IPO of up to $100 mln

* Kleopatra Holdings 1 SCA files for IPO of up to $100

million - SEC filing

Read more

Actelion says enters into exclusive discussions with J&J

ZURICH, Dec 21 (Reuters) - Actelion said on

Wednesday it has entered exclusive negotiations with U.S.

healthcare company Johnson & Johnson regarding what the

Swiss biotech company called a "possible strategic transaction".

Read more

UPDATE 1-Actelion re-enters talks with J&J in takeover twist

ZURICH, Dec 21 (Reuters) - The takeover battle surrounding

Actelion heated up on Wednesday when the Swiss biotech

company said it had begun exclusive talks with former suitor

Johnson & Johnson about a "strategic transaction".

Read more

BRIEF-Walgreens expands availability of naloxone without a prescription to 33 states and Washington D.C.

* Walgreens expands availability of naloxone without a

prescription to 33 states and washington d.c.

Source text for Eikon:

Further company coverage:

Read more

BRIEF-East China city reports new human H7N9 case - Xinhua

* A new human H7N9 avian flu case was reported in Xiamen

City, East China's Fujian Province - Xinhua

Read more

BRIEF-elexxion AG sees FY revenue slightly below previous yr's level

* Martin Klarenaar confirmed for another 5 years as sole management board member

Read more

BRIEF-Vigmed wins tenders in France and Sweden

* Vigmed, together with its distribution partners, wins

tenders in France and Sweden

Source text: http://bit.ly/2h1BfA3

Read more

BRIEF-Novartis signs licensing deal with Sunovion Pharma

* Novartis - signed licensing deal with Sunovion Pharma for

US commercial rights to its three treatments for chronic

obstructive pulmonary disease

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Natera provides constellation update

* Natera Inc - announced availability of a microdeletions

testing application for new and existing constellation licensees

worldwide

Read more

BRIEF-Lexicon reports positive top-line results in phase 3 study for sotagliflozin in patients with Type 1 diabetes

* Lexicon reports positive top-line results in second

pivotal phase 3 study for sotagliflozin in patients with type 1

diabetes

Read more

Artificial leaf copies nature to manufacture medicine

Dec 21 (Reuters) - Dutch scientists have developed an

artificial leaf that can act as a mini-factory for producing

drugs, an advance that could allow medicines to be produced

anywhere there is sunlight.

Read more

Deals of the day-Mergers and acquisitions

Dec 21 (Reuters) - The following bids, mergers, acquisitions

and disposals were reported by 1100 GMT on Wednesday:

Read more

BRIEF-Sygnis buys C.B.S. Scientific for us $0.9 mln

* Acquires profitable life sciences tools company C.B.S. Scientific for $0.9 million in cash

and shares

Read more

Actelion shares gain on report of progress in Sanofi talks

ZURICH, Dec 21 (Reuters) - Swiss biotech group Actelion's

shares rose by more than 3 percent on Wednesday

following a report that talks with Sanofi are making

progress, increasing optimism that the two will strike a deal.

Read more

BRIEF-NNIT extends agreement with Lundbeck

* Estimated total value of agreement consisting of three contracts will amount in high

double-digit million Danish crown range

Read more

BRIEF-Hansa Medical discontinues Phase II study in acquired TTP

* Discontinues its Phase II study in acquired Thrombotic Thrombocytopenic Purpura (TTP)

Read more

BRIEF-Hunan Fangsheng Pharma's buyout fund buys stake in health industry firm

* Says its buyout fund buys 51 percent stake in health

industry development firm for 258 million yuan ($37.13 million)

Read more

BRIEF-Sumitomo Dainippon Pharma plans merger between units

* Says co's wholly owned unit Boston Biomedical, Inc will

merge with co's another US-based unit Boston Biomedical Pharma,

Inc, on April 1, 2017

Read more

BRIEF-Enzymatica announces the results from the clinical study ENZY-002

* Says ENZY-002 did not meet its primary endpoint of

significantly lowering virus load compared to placebo in this

mild experimental model of common cold

Read more

Tuesday, December 20, 2016

BRIEF-BioInvent enters research collaboration, issues new shares to Pfizer

* Says announces cancer immunotherapy research collaboration

and license agreement with Pfizer and issues new shares to

Pfizer

Read more

BRIEF-Medy-Tox says annual cash dividend for 2016

* Says it will pay annual cash dividend at 1,300 won/share

for 2016

Read more

BRIEF-UMN Pharma announces exercise of options

* Says 150,000 units of its 20th series options were

exercised to 150,000 shares of its common stock on Dec. 21

Read more

Swiss stocks - Factors to watch on Dec 21

ZURICH, Dec 21 (Reuters) - Here are some of the main factors

that may affect Swiss stocks on Wednesday:

Read more

BRIEF-Fuan Pharmaceutical Group sees 2016 net profit to increase by 289 pct to 268.3 pct

* Sees net profit for 2016 to increase by 238.99 percent to

268.26 percent, or to be 220 million yuan to 239 million yuan,

compared to net profit of 2015 (64.9 million yuan)

Read more

BRIEF-Dezhan Health raises 1.51 bln yuan in private placement to fund acquisition, projects

* Says it issues new shares via private placement and raises

1.51 billion yuan in total, to fund acquisition and projects

Read more

BRIEF-Shinhung to dispose treasury shares for 25.1 mln won

* Says offering price is 10,150 won/share, 25.1 million won

in total

Read more

BRIEF-Fuan Pharmaceutical Group proposes 2016 dividend payment

* Says co's actual controller proposed to pay a cash

dividend of 2 yuan for every 10 shares and use additional

paid-in capital to distribute 20 new shares for every 10 shares,

as the dividend payment plan for 2016

Read more

BRIEF-Celltrion says annual stock dividend for 2016

* Says it will distribute annual stock dividend of 0.05 new

shares for each existing share

Read more

TPG Capital to acquire healthcare software provider Mediware

Dec 20 (Reuters) - Buyout firm TPG Capital LP has

agreed to acquire Mediware Information Systems Inc, a

healthcare technology company, from another private equity firm,

Thoma Bravo LLC.

Read more

BRIEF-Ionis Pharma - enters into separate privately negotiated exchange agreements

* Ionis pharma -on Dec 20, entered into separate privately

negotiated exchange agreements with certain holders of 2.75 pct

convertible notes due 2019

Source text for Eikon: [ID:http://bit.ly/2hXwDMR]

Further company coverage:

Read more

BRIEF-Agilent Technologies to acquire Multiplicom N.V.

* Agilent Technologies Inc - Agilent is acquiring

Multiplicom for approximately EUR68 million in cash

Read more

BRIEF-Centric Health to purchase 6.75 pct convertible notes

* Intends to purchase through facilities of Toronto stock

exchange for cancellation up to $2.75 million principal amount

Read more

BRIEF-U.S. FDA expands approved use of Dexcom's G5 mobile continuous glucose monitoring system

* The u.s. Fda expands approved use of dexcom's g5 mobile

continuous glucose monitoring system

Read more

BRIEF-Meridian Bioscience says Magellan Diagnostics signed exclusive distribution agreement with Medcaptain Medical Technology

* Meridian Bioscience Inc- Magellan Diagnostics business

unit has signed an exclusive distribution agreement with

Medcaptain Medical Technology Co., Ltd

Read more

BRIEF-TPG Capital to acquire Mediware Information Systems

* Mediware Information Systems Inc says additional terms of

transaction were not disclosed

Read more

Arizona agrees to drop use of contested sedative in executions

Dec 20 (Reuters) - Arizona has reached an agreement with

lawyers for death row inmates that would prohibit a sedative

that has been used in executions by lethal injection that took

longer than usual or were botched in several states.

Read more

UPDATE 1-U.S. extends review of Roche MS drug Ocrevus by three months

ZURICH, Dec 20 (Reuters) - The U.S. Food and Drug

Administration (FDA) has extended its review of Roche's

multiple sclerosis (MS) drug Ocrevus by three months to March

28, the Swiss drugmaker said on Tuesday.

Read more

UPDATE 1-Akebia in marketing deal for anemia drug with Japan's Otsuka

Dec 20 (Reuters) - Akebia Therapeutics Inc said it

signed a co-development and marketing deal worth up to $1

billion for its experimental anemia drug with Japan's Otsuka

Holdings Co Ltd.

Read more

BRIEF-Pharmstandard to terminate public status, apply for delisting from Moscow Exchange

* Says board decides to terminate public status of the

company and apply for delisting from Moscow Exchange

Read more

BRIEF-Biofrontera: EMA recommends indication expansion of ameluz for treatment of basal cell carcinoma

* European Medicines Agency recommends indication expansion

of ameluz for treatment of basal cell carcinoma

Read more

SPECIAL REPORT-How dependence on tax breaks corroded Puerto Rico's economy

ARECIBO, Puerto Rico, Dec 20 (Reuters) - Prudo Jimenez was

born on a sugar farm here in 1941, when agriculture ruled Puerto

Rico's economy. He grew up to be a supervisor for drug maker

Syntex in the 1960s, after U.S. manufacturers came in droves,

seeking a tax haven.

Read more

BRIEF-AlphaHelix sells BugScreener to Finland

Dec 20 (Reuters) - AlphaHelix Molecular Diagnostics AB

(publ) :

Read more

Deals of the day-Mergers and acquisitions

Dec 20 (Reuters) - The following bids, mergers, acquisitions

and disposals were reported by 1500 GMT on Tuesday:

Read more

BRIEF-Factor Therapeutics starts phase II trial of a novel topical biologic

* Factor Therapeutics announces commencement of phase II

trial of a novel topical biologic for the treatment of chronic

wounds

Read more

BRIEF-Pain Therapeutics to discuss remoxy ER with FDA

* Plans to meet with FDA in person on Monday, February 13,

2017 to discuss regulatory path forward for remoxy ER

Read more

BRIEF-Akebia Therapeutics entered into collaboration, license agreement with Otsuka Pharmaceutical on Dec. 18

* Akebia Therapeutics Inc - on December 18, 2016, co

entered into collaboration and license agreement with Otsuka

pharmaceutical co - sec filing

Read more

BRIEF-Telemedycyna Polska revenue in Nov. up 13.9 percent YoY

* Nov. revenue at 465,800 zlotys ($109,412), up 13.9 percent

versus year ago

Source text for Eikon:

Further company coverage:

($1 = 4.2573 zlotys)

(Gdynia Newsroom)

Read more

Laser therapy with deep-sea drug kills prostate cancer in trial

LONDON, Dec 20 (Reuters) - A non-surgical treatment for

low-risk prostate cancer in which doctors inject a

light-sensitive drug derived from deep-sea bacteria into a

patient's bloodstream was shown in a trial to kill cancer cells

without destroying healthy tissue.

Read more

BRIEF-Shanghai Shenqi Pharmaceutical Investment Management says shareholding changes

Dec 20 (Reuters) - Shanghai Shenqi Pharmaceutical Investment

Management Co Ltd :

Read more

BRIEF-Fresenius places 1 bln euros of Schuldschein loans

* Given the substantial investor demand, the volume of the

issuance was significantly upsized

Further company coverage:

Read more

UPDATE 1-GSK's two-drug HIV therapy shines in two big studies

* Dolutegravir and rilpivirine work well in Phase III tests

(Adds further reaction, more detail on competition)

Read more

BRIEF-Metalicity signs deal to acquire prospective lithium exploration portfolio from Fortescue Metals

* reached an agreement to acquire a highly prospective

lithium exploration portfolio

Read more

BRIEF-Regulator to halt review of Guilin Layn Natural Ingredients' private placement

* Says securities regulator to halt review of its share

private placement proposal

Read more

Monday, December 19, 2016

Swiss stocks - Factors to watch on Dec 20

ZURICH, Dec 20 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.1 percent higher at 8,245 points on Tuesday,

according to premarket indications by bank Julius Baer

.

Read more

BRIEF-Pharnext completes patient enrollment in Pivotal Phase 3 trial of PXT3003 for Charcot-Marie-Tooth Disease Type 1a

* Pharnext completes patient enrollment in international

pivotal phase 3 trial of PXT3003 for Charcot-Marie-Tooth Disease

Type 1a

Read more

BRIEF-Medical&Biological Laboratories to set up unit in China

* Says it to set up a wholly owned unit in China named MBL

Hangzhou Biotech Co., Ltd in Feb. 2017

Read more

BRIEF-UCB and Amgen seek marketing approval of romosozumab in Japan

* Says Amgen and UCB announce submission of

application for investigational osteoporosis medication

romosozumab in Japan

Read more

UPDATE 1-Japan to review drug prices more frequently to curb rising healthcare costs

TOKYO, Dec 20 (Reuters) - Japan said on Tuesday it planned

to start reviewing prescription drug prices once a year,

increasing their frequency from once every two years, as the

government tries to curb mounting healthcare costs in a rapidly

ageing society.

Read more

Hong Kong confirms first case of bird flu this season

HONG KONG, Dec 20 (Reuters) - Hong Kong authorities have

confirmed the first human bird flu infection for this season

after an elderly man who had recently travelled to mainland

China was diagnosed with the deadly H7N9 virus strain.

Read more

BRIEF-Sun Pharmaceutical Industries announces voluntary withdrawal of 28 ANDAs

* Says older drug products belong to erstwhile ranbaxy

laboratories ltd. And are not being marketed in us since 2008

Read more

BRIEF-Zhejiang Hisoar Pharmaceutical to raise up to 1.38 bln yuan via private placement

* Says it plans to raise up to 1.38 billion yuan via private

placement of shares issue

Read more

BRIEF-Viiv Healthcare announces positive results from first phase III studies of two-drug HIV treatment regimen

* Viiv Healthcare announces positive results from first

phase iii studies of two-drug HIV treatment regimen

Read more

BRIEF-Theravance biopharma highlights initiation of Phase 3 study

* Theravance Biopharma highlights initiation of phase 3

study of the closed triple in patients with asthma by

glaxosmithkline and innoviva

Read more

BRIEF-Janssen Sciences Ireland UC says positive results from first Phase III studies of investigational two-drug HIV treatment regimen

* Press release - Positive results from first Phase III

studies of investigational two-drug HIV treatment regimen

Read more

BRIEF-Conatus to receive $50 mln in liver drug deal with Novartis

* Conatus Pharmaceuticals Inc says full funding in position

for remaining development of Emricasan

Read more

UPDATE 2-Biogen names top executive Vounatsos as CEO

Dec 19 (Reuters) - Biogen Inc, the U.S. drug maker

focused on neurological, autoimmune and rare diseases, said on

Monday it had appointed its chief commercial officer, Michel

Vounatsos, as chief executive officer, ending a five-month

search.

Read more

BRIEF-Foundation Medicine receives FDA approval of Foundationfocus

* Foundation Medicine receives FDA approval of

Foundationfocus CDXBRCA as a companion diagnostic for

Rubraca(Rucaparib) for the treatment of women with ovarian

cancer

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Imprimis Pharmaceuticals announces $9.8 mln private placement of units

* Has agreed to sell an aggregate of approximately 5.1

million units at a purchase price of $1.915 per unit

Read more

Deals of the day-Mergers and acquisitions

Dec 19 (Reuters) - The following bids, mergers, acquisitions

and disposals were reported by 2100 GMT on Monday:

Read more

BRIEF-Sucampo announces proposed convertible senior note offering

* Sucampo Pharmaceuticals Inc says intention to offer

$225.0 million principal amount of convertible senior notes due

2021 in a private offering

Read more

BRIEF-Ceterix Orthopaedics Inc says raises about $23 mln in equity financing

* Ceterix Orthopaedics Inc says it has raised about $23

million in equity financing - SEC filing

Read more

CORRECTED-UPDATE 1-Ionis Pharma's rare metabolic disorder drug succeeds key study

Dec 19 (Reuters) - Ionis Pharmaceuticals Inc said

on Monday its rare metabolic disorder drug for severe

hypertriglyceridemia, characterized by elevated levels of a type

of fat in the blood, met the main goal in a late-stage study.

Read more

BRIEF-Anika wins CE mark approval for Orthovisc-T

* Anika wins CE mark approval for Orthovisc-T to relieve

pain and restore function of tendons damaged by chronic injury

Read more

Ducks culled in Bulgaria after bird flu found on three farms

SOFIA, Dec 19 (Reuters) - More than 4,000 ducks were culled

in Bulgaria over the past few days after bird flu was found on

three farms, the Bulgarian food safety agency said on Monday.

Read more

UPDATE 1-Clovis's ovarian cancer drug wins accelerated FDA approval

Dec 19 (Reuters) - The U.S. Food and Drug Administration

said on Monday it granted accelerated approval to Clovis

Oncology Inc's ovarian cancer drug in patients whose

disease advanced despite chemotherapy.

Read more

UPDATE 1-Japan to review drug prices annually rather than every two years -sources

TOKYO, Dec 19 (Reuters) - The Japanese government plans to

start reviewing drug prices every year, instead of every two

years, to try to reduce mounting healthcare costs, government

officials with direct knowledge of the decision said on Monday.

Read more

BRIEF-LENSAR strategic restructure in partnership with PDL Biopharma, Inc.

* LENSAR strategic restructure in partnership with PDL

Biopharma, Inc.

Read more

BRIEF-Kindred Healthcare, Atlantic Health System plans for inpatient rehabilitation hospital

* Kindred Healthcare Inc says joint venture will construct

and operate a 38-bed hospital in northern New Jersey

Read more

BRIEF-Endologix wins Australia approval for abdominal aortic aneurysm device

* Endologix receives australian therapeutic goods

administration (TGA) approval for AFX2 bifurcated endograft

system

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Adaptimmune, Bellicum Pharma collaborate to evaluate next-generation T-cell therapies

* Adaptimmune and Bellicum Pharmaceuticals enter a strategic

collaboration to evaluate next-generation T-cell therapies

Read more

BRIEF-EDAP TMS announces publication of results comparing Ablatherm focal HIFU with robotic radical prostatectomy

* EDAP TMS SA - Announced publication of results comparing

ablatherm focal HIFU with robotic radical prostatectomy

Read more

BRIEF-Prometic to submit biologics license application for plasminogen with U.S. FDA

* Prometic initiates rolling submission of its biologics

license application ("BLA") for plasminogen with U.S. FDA

Read more

BRIEF-Furen Pharma asks regulator to resume review of asset restructuring plan

Dec 19 (Reuters) - Furen Pharmaceutical Group Industry Co

Ltd

Read more

BRIEF-Lotus Pharmaceutical says Lin Tong-Ho retired from chairman

Dec 19 (Reuters) - Lotus Pharmaceutical :



* Says Lin Tong-Ho retired from chairman of the board



Source text in Chinese: https://goo.gl/gcc1xW



Further company coverage:

(Beijing Headline News)



Read more

BRIEF-Versant Ventures announces milestone with Northern Biologics and Bluerock Therapeutics

* Versant ventures announces milestone with recent Northern

Biologics and Bluerock Therapeutics deals

Read more

Japan to review drug prices annually vs every two years previously -sources

TOKYO, Dec 19 (Reuters) - The Japanese government plans to

start reviewing drug prices every year, instead of every two

years, in a bid to reduce mounting healthcare costs, government

officials with direct knowledge of the decision said on Monday.

Read more

Israel's BrainStorm to begin advanced trial for ALS stem cell treatment

TEL AVIV, Dec 19 (Reuters) - Israel's BrainStorm Cell

Therapeutics said it is proceeding to a Phase 3

clinical trial for its adult stem cell treatment in patients

with amyotrophic lateral sclerosis (ALS).

Read more

REFILE-UPDATE 1-Poultry culled in Germany after bird flu found on two farms

HAMBURG, Germany, Dec 19 (Reuters) - About 30,000 turkeys

and ducks were culled in Germany over the weekend after bird flu

was found on two farms, authorities said on Monday.

Read more

UPDATE 1-SCA to buy wound care firm BSN medical for 2.7 bln euros

STOCKHOLM, Dec 19 (Reuters) - Sweden's SCA said on

Monday it was buying German bandage and plaster cast maker BSN

medical for 2.74 billion euros ($2.9 bln) from private equity

firm EQT in a deal expected to boost the Swedish firm's growth.

Read more

Sunday, December 18, 2016

BRIEF-Grifols approves succession plan for CEO

* Appoints Raimon Grifols Roura and Victor Grifols Deu as

chief executive officers effective Jan. 1

Read more

BRIEF-Scandidos gets order on Delta4 Phantom+ to Greece

* Deliveries of therapy systems will be done separately for each hospital during period of

18 months while Delta4Phantom+ system will be delivered during Scandidos Q4

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

Swiss stocks - Factors to watch on Dec 19

ZURICH, Dec 19 (Reuters) - Here are some of the main factors

that may affect Swiss stocks on Monday:

Read more

BRIEF-Shionogi & Co Ltd signs strategic business alliance for sale of peripheral mu opioid receptor antagonist Symproic in U.S with Purdue Pharma L.P

* Says it signed a strategic business alliance for sale of

peripheral mu opioid receptor antagonist Symproic in U.S with

Purdue Pharma L.P

Read more

BRIEF-Kukje Pharma says annual stock dividend for 2016

* Says it will distribute annual stock dividend of 0.05 new

shares for each existing share

Read more

BRIEF-Shandong Sito Bio-technology issues prospectus for Shenzhen IPO

Source text in Chinese: http://bit.ly/2gQfUtj

(Reporting by Beijing newsroom)

Read more

BRIEF-Cell Biotech says annual cash dividend for 2016

* Says it will pay annual cash dividend at 550 won/share for

2016

Read more

BRIEF-Dorsavi signs a 12-month contract to deliver visafe services

* Signed a 12-month contract which will see dorsavi deliver

a range of visafe services in three phases

Read more

PRESS DIGEST- Financial Times - Dec 19

Dec 19 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

Read more

BRIEF-Proteomics International Laboratories says Diabetic Kidney Disease patent granted in Russia

Dec 19 (Reuters) - Proteomics International Laboratories Ltd

:

Read more

BRIEF-A Soriano Corp signs deal to sell property for 397.1 mln pesos

* Signed a deed of absolute sale dated dec 16 for sale of

its Cebu Business Park Lot to Skyrise Realty And Development

Corporation

Read more

BRIEF-Simavita says received $1.7 mln R&D tax incentive

* Confirms receipt of $1.7 million under Australian

Government's research and development tax incentive scheme

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Universal Biosensors' unit acquires hemostasis reference laboratory business

* Canada unit signed an agreement with Lifelabs LP to

acquire assets of Lifelabs' hemostasis reference laboratory

business

Read more

BRIEF-SCA nearing deal to buy BSN Medical for 2.7 bln euros- FT,citing sources

* Sweden's SCA is nearing a deal to buy bsn medical for 2.7

billion euros including debt- FT,citing sources

Read more

Saudi Aramco, GE to launch Saudi Arabia's first wind turbine next month

KHOBAR, Saudi Arabia, Dec 18 (Reuters) - Saudi Aramco plans

to commission its wind turbine pilot project, the first in the

kingdom, next month, the state oil company said on Sunday, part

of nationwide plans to diversify energy supplies and to meet an

increase in demand.

Read more

BRIEF-Polynovo appoints Gavin Smith as interim CFO

* Gavin Smith appointed as interim cfo

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Yonker Environmental Protection to set up health insurance JV

* Says it to set up a health insurance JV with a Tibet-based

investment firm, Hunan TV & Broadcast Intermediary Co Ltd

, Talkweb Information System Co Ltd,

Centre Testing International Group Co Ltd, and

Chongqing Lummy Pharmaceutical Co Ltd

Read more

Saturday, December 17, 2016

BRIEF-Zhejiang Hisun Pharmaceutical appoints Guan Xuhua as CFO

Dec 17 (Reuters) - Zhejiang Hisun Pharmaceutical Co Ltd

:



* Says it appoints Guan Xuhua as CFO to replace Hu Liangbin



Source text in Chinese: https://goo.gl/aWixl4



Further company Coverage:

(Beijing Headline News)



Read more

China considers national appeals court on intellectual property rights - paper

BEIJING, Dec 17 (Reuters) - China is considering a national

appeals court specializing in intellectual property rights, the

China Daily has cited a senior Chinese judge as saying, as the

world's second-largest economy tightens regulation of patents

and trademarks.

Read more

BRIEF-Guangzhou Wondfo Biotech to hold 51 pct stake in biotechnology firm

* Says it to hold 51 percent stake in a Xiamen-based

biotechnology firm after stake acquisition and capital injection

Read more

Friday, December 16, 2016

BRIEF-James Flynn reports 10.9 pct passive stake in Recro Pharma Inc

* James flynn reports 10.9 percent passive stake in recro

pharma inc as of dec. 16, 2016 - sec filing

Source text http://bit.ly/2gUriaR

Further company coverage:

Read more

UPDATE 1-U.S. lawmakers press Heritage Pharma on high prices for antibiotic

WASHINGTON, Dec 16 (Reuters) - Two U.S. lawmakers are

questioning whether Heritage Pharmaceuticals misled them in

response to a 2014 congressional inquiry about the rising price

a common antibiotic, after 20 U.S. states this week accused the

company of price fixing.

Read more

Canadian marijuana companies look to get creative with brand building

OTTAWA, Dec 16 (Reuters) - Canadian marijuana firms, facing

potential limits on advertising for recreational pot, are

selling health food products and cultivating a lifestyle image

to win customers in an anticipated multibillion dollar market.

Read more

BRIEF-Amarin corp says providing contractual reminder to holders of 3.50% senior notes

* Amarin Corp says providing contractual reminder to holders

of outstanding 3.50% exchangeable senior notes due 2032 of its

wholly owned subsidiary, corsicanto

Read more

BRIEF-Casi Pharmaceuticals Inc entered into amendment with Talon Therapeutics

* Casi Pharmaceuticals Inc - pursuant to first amendment,

company and talon agreed to change maturity date of note to

march 17, 2017 - SEC filing

Read more

FDA drops black box warning on Pfizer's anti-smoking drug

Dec 16 (Reuters) - U.S. health regulators on Friday allowed

Pfizer Inc to remove a serious warning from the label of

its smoking cessation treatment, Chantix, giving a new lease of

life to the controversial drug that was approved a decade ago.

Read more

BRIEF-Pfizer says FDA drops black box warning on anti-smoking drug Chantix

* FDA approves removal of boxed warning regarding serious

neuropsychiatric events from Chantix (Varenicline) labeling

Read more

Fitch Revises Sanofi's Outlook to Negative; Affirms IDR at 'AA-'

(The following statement was released by the rating agency)

LONDON, December 16 (Fitch) Fitch Ratings has revised French

pharmaceutical

company Sanofi SA's Outlook to Negative from Stable and affirmed

the group's

Long-Term Issuer Default Rating (IDR) at 'AA-'. Fitch has also

affirmed the

senior unsecured rating 'AA-' and Short-term IDR at 'F1+'.

The revision of the Outlook to Negative reflects Fitch's belief

that Sanofi's

financial leverage, cash generation and liquidity will be

affected by

Read more

BRIEF-Xbiotech says received Day 180 List Of Outstanding Issues from EMA for Xilonix - SEC filing

* Xbiotech-Announced it received Day 180 List Of Outstanding

Issues from European Medicines Agency's Committee for Medicinal

Products for Human Use

Read more

BRIEF-MiMedx 2017 guidance forecasts revenue growth in excess of 21%, operating earnings growth in excess of 90%

* MiMedx 2017 guidance forecasts revenue growth in excess of

21% and operating earnings growth in excess of 90%

Read more

BRIEF-Adocia and Lilly announce successful completion of an insulin pump study with BioChaperone Lispro in people with type 1 diabetes

* Adocia and Lilly announce successful completion of an

insulin pump study with Biochaperone Lispro in people with Type

1 diabetes

Read more

BRIEF-Pharmacolog: First Swedish hospital signs DrugLog agreement

* Blekinge Hospital in Karlskrona will be the first hospital

in Sweden to sign agreement for the use of DrugLog

Read more

BRIEF-RLS Global to carry out directed new issue and rights issue totaling SEK 70 mln

* Says has decided to carry out a directed new issue and a

rights issue totaling 70 million Swedish crowns ($7.46 million)

Read more

BRIEF-Ophthotech determined to implement reduction in personnel to focus on updated business plan

* Ophthotech Corp - determined to stop treating patients who

are in second twelve months of both its phase 3 clinical trials

Read more

BRIEF-Amgen receives positive response from EMA for its single-dose delivery injection Repatha

* Top-line results from approximately 27,500-patient

event-driven fourier study are anticipated in q1 of 2017

Read more

BRIEF-Yichang Hec Changjiang Pharmaceutical Co enters capital increase agreement with parent co

Dec 16 (Reuters) - Yichang Hec Changjiang Pharmaceutical Co

Ltd

Read more

UPDATE 1-Mylan launches EpiPen generic at more than 50 pct discount

Dec 16 (Reuters) - Mylan NV said on Friday it would

start selling a generic version of its life-saving EpiPen

allergy treatment at a more than 50 percent discount, a day

after 20 U.S. states filed a lawsuit against generic drugmakers

including Mylan over prices.

Read more

BRIEF-Formonar Investments raises stake in Infoscan to 20.39 pct

* Cyprus-based Formonar Investments Limited raises stake in

the company to 20.39 percent from 7.99 percent through the

acquistion of about 0.3 mln of shares

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Alnylam Pharmaceuticals announces positive preliminary results from phase 1 study of ALN-TTRsc02

* Alnylam Pharmaceuticals- assuming positive phase 3 data,

co plans to submit NDA,marketing authorisation application

year-end 2017

Read more

BRIEF-QT Vascular gains FDA approval to begin trial of drug related device

* Full ide approval to begin pivotal trial of its

drug-coated balloon, chocolate touchtm

Read more

Aleppo evacuation halted without explanation - WHO

GENEVA, Dec 16 (Reuters) - The evacuation of wounded and

civilians from eastern enclaves of Aleppo was aborted on Friday,

and aid agencies and vehicles told to leave the area without

explanation, the World Health Organization (WHO) said on Friday.

Read more

BRIEF-Tongfang Kontafarma announces subscription of equity interest in Binex Co

* Total subscription consideration for the deal is krw210.92

billion

Read more

BRIEF-Haisco Pharma to sell 18 pct stake in Haisthera Associates

* Says it plans to sell 18 percent stake in Haisthera

Associates to Haisthera Advisor for $198,700

Read more

Thursday, December 15, 2016

BRIEF-Care Service to set up unit in Japan

* Says the unit to be engaged in human resource agency

business, recruitment worker, temporary staffing business

Read more

BRIEF-UK's CMA provisionally finds Actavis UK has broken competition law

* Has provisionally found that Actavis UK has broken

competition law by charging excessive prices to NHS for

hydrocortisone tablets.

Read more

Novartis says buys Ziarco Group to expand skin care portfolio

ZURICH, Dec 16 (Reuters) - Novartis is buying

privately held drugmaker Ziarco Group for an undisclosed sum to

gain access to its investigational eczema medicine, the Swiss

pharmaceutical giant said on Friday.

Read more

Swiss stocks - Factors to watch on Dec 16

ZURICH, Dec 16 (Reuters) - The following are some of the

main factors expected to affect Swiss stocks on Friday:

Read more

BRIEF-Alembic Pharma gets USFDA nod for itraconazole capsules

* Alembic Pharmaceuticals receives USFDA approval for

itraconazole capsules

Read more

BRIEF-Guangdong Zhongsheng Pharmaceutical sets up ophthalmic investment management unit

Dec 16 (Reuters) - Guangdong Zhongsheng Pharmaceutical Co.,

Ltd. :

Read more

BRIEF-Sincere lists on TSE Mothers

Dec 16 (Reuters) - Sincere Co Ltd :



* Says it began listing on TSE Mothers on Dec. 16



Source text in Japanese: https://goo.gl/1Z7zb7



Further company Coverage:

(Beijing Headline News)



Read more

BRIEF-Amicus Therapeutics prices convertible senior notes offering

* notes to bear interest at 3.00% per annum, payable

semi-annually on June 15 & Dec 15 of each year, beginning on

June 15, 2017

Read more

Obamacare repeal could take months; replacement, years -Republican aides

WASHINGTON, Dec 15 (Reuters) - Repealing Obamacare could

take months and developing replacement health insurance plans

could take years, senior Republican aides in the U.S. Congress

said on Thursday, discouraging talk of a quick end to the

program after President-elect Donald Trump takes office on Jan.

20.

Read more

BRIEF-AFT Pharmaceuticals says request for proposal issued by PHARMAC

* RFP seeks proposals for either dual listing or sole supply

of metoprolol in New Zealand with submission due date of 27 jan

2017

Read more

UPDATE 2-U.S. judge halts Texas rules on fetal tissue disposal

AUSTIN, Texas, Dec 15 (Reuters) - A U.S. judge on Thursday

temporarily halted until Jan. 6 a Texas regulation that would

require abortion providers to dispose of aborted fetal tissue

through burial or cremation, court documents showed.

Read more

UPDATE 1-U.S.-based stock ETFs rake in cash as Fed raises rates -Lipper

(Adds data on mutual funds and ETFs, context, analyst quote,

table, byline)

By Trevor Hunnicutt

NEW YORK, Dec 15 (Reuters) - Investors piled into stock

exchange-traded funds at the fastest pace since their

record-setting haul following the U.S. presidential election,

Lipper said on Thursday, as policymakers raised interest rates.

U.S.-based equity ETFs took in nearly $18 billion in cash in

the seven days through Wednesday, while U.S.-based stock mutual

funds posted cash withdrawal

Read more

BRIEF-Vericel corporation announces proposed public offering of common stock

* Vericel-Net proceeds to be used primarily to support

commercialization of maci, expand promotional efforts for

epicel, expand, optimize manufacturing

Read more

BRIEF-Aceto Corp comments on recent announcements impacting generic pharmaceuticals industry

* Commented today on recent announcements impacting generic

pharmaceuticals industry

Read more

Rotation from U.S.-based bond funds to stocks accelerates -Lipper

NEW YORK, Dec 15 (Reuters) - Investors poured $6.8 billion

into U.S.-based stock funds in the week through Dec. 14, Lipper

data showed on Thursday, accelerating a rotation from bonds to

stocks as U.S. policymakers raised interest rates for the first

time in a year.

Read more

BRIEF-Milestone Scientific reports proposed public offering of common stock and warrants

* Milestone Scientific Inc announces proposed public

offering of common stock and warrants

Source text for Eikon:

Further company coverage:

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Chemical companies pitch bug-killing options amid neonic farm bans

WINNIPEG, Manitoba, Dec 15 (Reuters) - Companies that make

bug-killing chemicals and natural remedies are racing to take

advantage of restrictions on neonics, a type of insecticide

popular with farmers but blamed for harming bees and mayflies.

Read more

BRIEF-Sunshine Heart files for resale of up to 4.1 mln shares

* Files for resale of up to 4.1 million shares of co's

common stock - sec filing

Read more

BRIEF-Allergan announces civil resolution concluding federal investigation into Forest sales & marketing practices

* Allergan announces civil resolution concluding federal

investigation into Forest sales & marketing practices

Read more

UPDATE 2-U.S. states sue Mylan, Teva, others for fixing drug prices

WASHINGTON, Dec 15 (Reuters) - Two years after high generic

drug prices became a public controversy, legal cases are

starting to land.

Read more

BRIEF-Aptevo Therapeutics amends collaboration agreement with Morphosys AG for Novel Immunotherapeutic

* Under terms of third amendment, Aptevo Research and

Development will bear 75 pct of all development costs with

respect to MOR209/es414

Read more

UPDATE 1-Britain agrees to license three-parent IVF babies to prevent disease

LONDON, Dec 15 (Reuters) - Britain on Thursday became the

first country to formally license an in-vitro fertilisation

(IVF) treatment designed to create babies from three people.

Read more

Aid trucks with medical supplies leave Paris for northern Syria

PARIS, Dec 15 (Reuters) - Two trucks filled with 20 tonnes

of first aid supplies and construction materials left Paris for

northern Syria on Thursday to help those fleeing conflict in

Aleppo.

Read more

UPDATE 3-Lilly eases investors' jitters with strong 2017 forecast

* Shares jump 4.4 percent

(Adds analyst, company comment, background; updates shares)

Read more

BRIEF-Abivax appoints Didier Blondel as Chief Financial Officer

* Chief Financial Officer appointment effective January 2(nd), 2017

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Ahead Global Investment publishes final results of mandatory offer on MediRox, delisting of company initiated

* Ahead Global Investment Ltd publishes final results of mandatory offer on MediRox AB

(publ), delisting of company initiated

Read more

Fitch Rates UnitedHealth Group's Planned Issuance 'A-(EXP)'

(The following statement was released by the rating agency)

CHICAGO, December 15 (Fitch) Fitch Ratings has assigned an

'A-(EXP)' rating to

UnitedHealth Group Incorporated's (UNH) planned benchmark

offering of senior

unsecured notes in a mix of 10 and 30 year maturities. Fitch

expects the

issuance to be between $1.0 billion and $1.5 billion. The

ratings are equivalent

to Fitch's ratings on UNH's outstanding senior unsecured notes.

UNH's 'A' Issuer

Default Rating (IDR) Outlook is currently Ne

Read more

BRIEF-EnteroMedics says Commercial Patient Data confirms success of co's vBloc therapy in combination with vBloc achieve program

* Commercial Patient Data confirms success of EnteroMedics'

vBloc therapy in combination with vBloc achieve program in

patients struggling to lose weight

Source text for Eikon:

Further company coverage:

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EU lawmakers urge Germany to broaden access to thalidomide fund

STRASBOURG, Dec 15 (Reuters) - EU lawmakers urged Germany on

Thursday to grant broader access for other Europeans to its fund

for thalidomide victims and for the drug's manufacturer to

provide proper compensation and care to victims not yet

recognised.

Read more

BRIEF-PacBio announces termination of agreement with Roche Diagnostics

* Product and service revenue for 2016 is on pace to grow

between 55% and 65% over 2015

Read more

BRIEF-GE appoints three new company officers

* Visal Leng is president and ceo, asia pacific, GE oil &

gas

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BRIEF-Knight Therapeutics announces exclusive license agreement with AstraZeneca

* Knight therapeutics- as per agreement, co will be

responsible for all commercial, regulatory, certain supply chain

activities for movantik in canada, israel

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BRIEF-Papilly signs two new agreements

* Signs agreements with one company in construction sector

and one in staffing sector

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BRIEF-NOXXON Pharma signs clinical immuno-oncology collaboration agreement with MSD to study NOX-A12 combined with Keytruda (Pembrolizumab) in pancreatic and colorectal cancer

* Two companies will collaborate in a Phase 1/2 clinical trial of NOXXON's ANTI-CXCL12

agent, NOX-A12, and MSD's anti-PD-1 inhibitor, Keytruda (Pembrolizumab)

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UPDATE 1-Philips, Infineon lose appeal against EU cartel fines

LUXEMBOURG, Dec 15 (Reuters) - Philips and Infineon

lost an appeal on Thursday against a combined 102.9

million euro ($107.8 million) cartel fine after a European court

said EU antitrust regulators was correct to find they had fixed

prices of smart card chips.

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BRIEF-Top Glove Corporation Bhd seeks trading halt

* Top glove corporation seeks trading halt pending co's

quarterly report on consolidated results for financial period

ended 30 Nov 2016.

Source text for Eikon:

Further company coverage:

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EU court dismisses Philips, Infineon action against cartel fine

LUXEMBOURG, Dec 15 (Reuters) - An EU court on Thursday

dismissed an appeal brought by Philips and Infineon

against a fine imposed on by the European Commission

for operating a cartel to manipulate prices for smart card

chips.

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Spain's Grifols plans to refinance debt in Q1 2017 after Hologic buy

MADRID, Dec 15 (Reuters) - Spain's Grifols, which

on Wednesday said it would buy U.S. Hologic Inc's

assets in their blood screening joint venture, will refinance

its net debt in the first quarter of next year, its Chief

Financing Officer said on Thursday.

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BRIEF-Chiome Bioscience announces exercise of options

* Says 1,890 units of its 13th series options were exercised

to 1.89 million shares of its common stock from Dec. 6 to Dec.

15

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Wednesday, December 14, 2016

German stocks - Factors to watch on December 15

FRANKFURT, Dec 15 (Reuters) - The DAX top-30 index

looked set to open 0.2 percent higher on Thursday, according to

premarket data from brokerage Lang & Schwarz at 0708 GMT.

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BRIEF-Scandidos Q2 EBITDA loss widens to SEK 1.3 million

* Q2 net sales 11.3 million Swedish crowns ($1.2 million)

versus 10.4 million crowns year ago

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BRIEF-Takara Bio signs exclusive license agreement of Oncolytic virus HF10 with Otsuka Pharmaceutical

* Says it signed an exclusive license agreement of Oncolytic

virus HF10 with Otsuka Pharmaceutical

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BRIEF-Takara Bio unit to buy Rubicon Genomics

* Says its unit Takara Bio USA Holdings Inc plans to acquire

Rubicon Genomics, Inc in early Jan. 2017

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Japan's Fujifilm to announce acquisition at 0600 GMT

TOKYO, Dec 15 (Reuters) - Japan's Fujifilm Holdings Corp

said it will hold a press conference at 0600 GMT on

Thursday in Tokyo to announce a planned acquisition.

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BRIEF-Top Glove Corporation says qtrly profit attributable is 73.3 mln RGT

* Qtrly profit attributable 73.3 million rgt vs 128.3

million rgt; qtrly revenue 785.6 million rgt vs 800.3 million

rgt

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BRIEF-I'rom Group buys 61 pct stake in CMAX Clinical Research

* Says it acquired 61 percent stake in CMAX Clinical

Research Pty Ltd from IDT Australia Limited for AU$10 million

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BRIEF-Meganesuper and Alcon Japan to buy MEGANE HOUSE for 300 mln yen

* Says the co and Alcon Japan Ltd to buy MEGANE HOUSE CO.LTD

for 300 million yen on Jan. 31, 2017

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MIDEAST STOCKS - Factors to watch - Dec 15

Dec 15 (Reuters) - Here are some factors that may affect

Middle East stock markets on Thursday. Reuters has not verified

the press reports and does not vouch for their accuracy.

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PRESS DIGEST- Financial Times - Dec 15

Dec 15 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

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