Thursday, June 30, 2016

BRIEF-AstraZeneca enters licensing agreements with Leo Pharma in skin diseases

* Enters licensing agreements with Leo Pharma in skin

diseases

Read more

German stocks - Factors to watch on July 1

FRANKFURT, July 1 (Reuters) - The DAX top-30 index

looked set to open 0.4 percent higher on Friday, according to

premarket data from brokerage Lang & Schwarz at 0619 GMT.

The following are some of the factors that may move German

stocks:

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Swiss stocks - Factors to watch on July 1

ZURICH, July 1 (Reuters) - The following are some of the

main factors expected to affect Swiss stocks on Friday:

Read more

Spanish stocks - Factors to watch on Friday

The following Spanish stocks may be affected by newspaper

reports and other factors on Friday. Reuters has not verified

the newspaper reports, and cannot vouch for their accuracy:

Read more

BRIEF-Bionime says 2015 dividend record date is Aug. 3

* Last date before book closure July 29 with book closure

period from July 30 to Aug. 3

Read more

BRIEF-Zhejiang Jiuzhou Pharmaceutical to get stakes in Frontage laboratories unit

July 1 (Reuters) - Zhejiang Jiuzhou Pharmaceutical Co., Ltd.

:

Read more

BRIEF-Kolen receives patent for photographic lens optical system

* Says it receives patent on June 30, for photographic lens

optical system

Read more

BRIEF-Guangdong Biolight Meditech to get stakes in medical device firm for 60 mln yuan

* Says it plans to acquire 60 percent stake in a

Changzhou-based medical device firm from two individuals

Read more

UPDATE 1-China factory activity stalls in June, more stimulus expected

BEIJING, July 1 (Reuters) - Growth in China's manufacturing

sector stalled in June, an official survey showed on Friday,

adding to expectations that Beijing will have to roll out more

stimulus soon to boost the sluggish economy.

Read more

BRIEF-InspireMD announces pricing of public offering of approximately $14.6 mln

* Each share of series B convertible preferred stock is

convertible into 100 shares of common stock at price equal to

$0.33 per share

Read more

BRIEF-Array biopharma submits Binimetinib new drug application to U.S. FDA

* Array biopharma submits binimetinib new drug application to u.s. Fda

Read more

UPDATE 1-NuVasive settles spinal surgery patent fight with Medtronic

June 30 (Reuters) - Medical device maker NuVasive Inc

will pay rival Medtronic Plc $45 million to

settle a longstanding patent fight related to spinal surgery

technology, NuVasive said on Thursday.

Read more

BRIEF-Vivus says to extend return date of Stendra commercial rights

* Vivus Inc says to extend return date of Stendra commercial

rights

Read more

BRIEF-Vitae Pharmaceuticals entered controlled equity offering sales agreement with Cantor Fitzgerald & Co on June 30 - SEC Filing

* On June 30, co entered into controlled equity offering

sales agreement with Cantor Fitzgerald & Co - SEC Filing

Read more

BRIEF-Healthstream buys Performance Management Services

* Healthstream acquired PMSI through a merger for

approximately $4.0 million in cash at closing

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Novocure announces $75 mln drawdown under term loan agreement

* Novocure drew $25 million of total $100 million available

borrowing capacity when term loan agreement closed in January

2015

Read more

UPDATE 1-U.S. doctors, hospitals paid billions by drug, device makers -gov't

NEW YORK, June 30 (Reuters) - Doctors and hospitals in the

United States received $7.52 billion in payments and ownership

and investment interests from the makers of drugs and medical

devices in 2015, according to data released by a government

health agency.

Read more

Two of three German A400M planes grounded due to engine issues-ministry

BERLIN, June 30 (Reuters) - Germany has grounded two of its

three A400M military transport planes delivered by Airbus Group

SE due to newly discovered gearbox issues on their

turboprop engines, a spokesman for the German defence ministry

said on Thursday.

Read more

More U.S. babies with Zika-related birth defects reported by health agency

June 30 (Reuters) - Three more babies have been born in the United States with birth defects likely linked to Zika virus infections, while another lost pregnancy was linked to the virus, according to figures updated by health officials on Thursday.

Read more

BRIEF-Prim says price of the deal with Laboratorios Milo is not defined

* Says acquisition price of the branches of Laboratorios Milo SA will not be established

until the end of negotiations, with the date scheduled for Sept 1

Read more

RPT-U.N. peacekeeping mission leaves Liberia after 13 years

MONROVIA, June 30 (Reuters) - A U.N. peacekeeping mission

that was sent to Liberia in 2003 to restore order after two

brutal civil wars withdrew on Thursday, beginning a new phase of

self-reliance for the impoverished West African country.

Read more

UPDATE 1-EU mergers and takeovers (June 30)

BRUSSELS, June 30 (Reuters) - The following are mergers

under review by the European Commission and a brief guide to the

EU merger process:

Read more

BRIEF-Quantum Genomics initiates phase IIa trial for heart failure

* Opening of the first hospital centres in france and

norway, and the beginning of the phase iia study in heart

failure

Read more

BRIEF-Excelsior Medical to pay 2015 dividend on Aug. 31

* Says it will pay cash dividend of T$304,451,400 in total

for 2015

Read more

BRIEF-Ascendis Health says intends to raise 1.2 billion rand via rights offer

* Intends to raise r1.2 billion, through a fully

underwritten renounceable rights offer to part settle purchase

consideration of acquisitions.

Read more

BRIEF-Tesaro files for mixed shelf offering - SEC filing

* Says files for mixed shelf offering with the U.S. SEC;

size undisclosed - SEC filing

Source: (http://1.usa.gov/295fkJh

)

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

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Mylan offers EC concessions to get approval for $7.2 bln Meda buy

BRUSSELS, June 30 - U.S. generic drugmaker Mylan NV

has offered concessions in a bid to allay concerns by EU

competition regulators over its proposed $7.2-billion

acquisition of Swedish rival Meda, the European

Commission said on Thursday.

Read more

BRIEF-Galmed Pharmaceuticals says enters research collaboration agreement

* Has right to enter into exclusive negotiations with Yeda

to complete license agreement to commercialize diagnostic,

prognostic tool for Aramchol

Read more

BRIEF-Aratana Therapeutics files for FDA approval of Nocita

* Aratana Therapeutics files for FDA approval of

Nocita(bupivacaine liposome injectable suspension)

Read more

BRIEF-Shire reports results for mid-stage trial of shp607 in extremely premature infants

* Shire announces top-line results for phase 2 trial of

shp607 in extremely premature infants

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Beijing Science Sun Pharmaceutical unit's GMP certificate to be withdrawn

June 30 (Reuters) - Beijing Science Sun Pharmaceutical Co

Ltd :

Read more

COLUMN-Keep Medicare advice SHIP afloat for U.S. seniors

CHICAGO, June 30 (Reuters) - Would you call a U.S. program

that helps 7 million seniors save money on Medicare annually

"unnecessary"?

Read more

BRIEF-Arqule says presents preliminary clinical data for ARQ 087

* Presents preliminary clinical data for arq 087

demonstrating evidence of anticancer activity in intrahepatic

cholangiocarcinoma

Read more

Deals of the day- Mergers and acquisitions

June 30 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1000 GMT on

Thursday:

Read more

BRIEF-Prim to buy branches of Laboratorios Milo

* Reaches agreement with Laboratorios Milo SA to buy pharmaceutical, orthopedic and

podiatric branches of activity

Read more

BRIEF-Medistim's technology has achieved reimbursement in Japan

* Valid from April 1, 2016, Ministry of Health, Labour and Welfare in Japan approved a

reimbursement of YEN 25,000 [EUR 225] when blood flow of the graft is controlled, using either

transit time flow measurement or high-resolution epicardial ultrasonography intraoperatively

Read more

BRIEF-Pierrel receives payments for a future capital increase from two shareholders

* Said on Wednesday that shareholder Fin Posillipo SpA,

owner of a 36.4 percent stake in Pierrel, made a payment for a

future capital increase of 0.85 million euros ($944,690.00)

Read more

BRIEF-Bioleaders to list shares on KOSDAQ

* Says it will issue 1.2 million shares on Korea Securities

Dealers Automated Quotations Stock Market

Read more

BRIEF-Merck KGaA says Zeiss, Hamilton Thorne to join global fertility alliance

* Says welcomes Zeiss and Hamilton Thorne as new members of

global fertility alliance

Source text for Eikon:

Further company coverage:

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BRIEF-Hungary's Richter to finance Finox deal from cash -CEO

* Finox closing will take place in July, to consolidate from

H2 2016

Read more

BRIEF-Mithra announces update on European phase III clinical trials for its estetrol-based product candidate Estelle

* Announces that first patient has been screened for

enrolment in European phase III clinical trials for its

estetrol-based product candidateEstelle

Read more

UPDATE 3-Japan regulator approves Canon deal to buy Toshiba unit, warns on method

* Unorthodox deal structure allowed Toshiba to raise cash in

hurry

(Recasts with regulator approval and comments)

Read more

Wednesday, June 29, 2016

BRIEF-Genovis and Promega reach agreement in patent dispute

* Genovis and Promega have reached agreement in patent dispute

Read more

BRIEF-Orexo signs license agreement with Mundipharma, which obtains ex-US global rights to Zubsolv

* signs license agreement with Mundipharma, which obtains

ex-us global rights to Zubsolv

Read more

BRIEF-Probiodrug and Crossbeta Biosciences enter into strategic partnership

* Probiodrug and Crossbeta Biosciences enter into a

strategic partnership in the field of Alzheimer's disease

biomarkers

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Kiadis Pharma's ATIR101, has been granted an expansion to its existing orphan drug designation

* Kiadis Pharma's orphan drug designation for ATIR101 further expanded to include treatment

in a hematopoietic stem cell transplantation

Read more

CORRECTED-BRIEF-DNA Link to raise up to 1 bln won via private placement

* Says it will raise up to 1 billion won via private

placement

Read more

BRIEF-Yongan Pharma's Wuhan unit investigated by Tianjin authorities on a health product

* Says unit Yongan Health Pharmaceutical (Wuhan) Co Ltd

being investigated by Tianjin authorities on a health product

Read more

BRIEF-TSH Biopharm to pay 2015 div on Aug. 19

* Last date before book closure July 19 with book closure

period from July 20 to July 24

Read more

BRIEF-Guilin Sanjin Pharmaceutical to fully buy health products firm for 50.6 mln yuan

* Says it will buy 100 percent stake in a Guilin-based

health products company, from the controlling shareholder of the

company, for 50.6 million yuan

Read more

BRIEF-Guilin Sanjin Pharmaceutical to fully buy canned food firm for 8.4 mln yuan

* Says it will buy 100 percent stake in a Guilin-based

canned food company, from the controlling shareholder of the

company, for 8.4 million yuan

Read more

BRIEF-Syros pharmaceuticals prices IPO of 4 mln shares of its common stock at a public offering price of $12.50 per share

* Pricing of IPO of 4 million shares of its common stock at

a public offering price of $12.50 per share

Read more

BRIEF-Guangdong Zhongsheng Pharmaceutical receives invention patent

June 30 (Reuters) - Guangdong Zhongsheng Pharmaceutical Co

Ltd :

Read more

FEATURE-Children face "staggeringly high" hunger in conflict-hit Central African Republic

BANGUI, June 30 (Thomson Reuters Foundation) - Clinging to

her toy dog, 18-month-old Clemence Mokbem stares ahead as nurses

rush past to tend to crying babies in the hot, overcrowded

intensive care ward in a Bangui hospital.

Read more

PRESS DIGEST- Financial Times - June 30

June 30 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

Read more

BRIEF-Onconova announces price range for rights offering

* Onconova announces price range and change of key dates for

rights offering

Read more

BRIEF-Cesca Therapeutics files for mixed shelf of up to $30 mln

* Files for mixed shelf of up to $30.0 million - SEC filing

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-FDA clears Xpert Carba-R Assay test to detect specific genetic markers

* Clears Xpert Carba-R Assay, test to detect specific

genetic markers for certain antibiotic-resistant bacteria

directly from clinical specimens

Source text: (http://1.usa.gov/296qiLy)

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Great Basin Scientific entered into securities purchase agreement to issue $75 mln in senior secured convertible notes

* Entered into securities purchase agreement to issue $75

million in principal face amount of senior secured convertible

notes

Read more

Olympics will come and go but Zika is here to stay, scientists say

RIO DE JANEIRO, June 29 (Reuters) - Battered by a presidential impeachment and the worst recession since the Great Depression, Brazil is getting a rare bit of relief as Rio de Janeiro prepares to host the Olympics: declining numbers of Zika infections.

Read more

BRIEF-VCA Inc announces new $1.68 bln senior credit facility

* Increased its credit facility by approximately $300

million by entering into a new $1.68 billion senior credit

facility

Read more

BRIEF-Monsanto seeks up to $7 bln more from Bayer in takeover-Handelsblatt

June 29 (Reuters) - ** The U.S. seed producer has

demanded that Germany's Bayer increase its takeover offer by

$10-15 per share, unnamed sources tell German business daily

Handelsblatt.

Read more

Fitch: U.S. Hospitals Experiencing Weaker Volumes of Less Acute Patients

(The following statement was released by the rating agency)

NEW YORK, June 29 (Fitch) A group of the largest Fitch-rated

U.S. for-profit

hospital companies reported an average of 0.2% organic growth in

inpatient

admissions and 2.8% organic growth in admissions adjusted for

outpatient

activity in first quarter 2016 (1Q16). Year-over-year rates of

growth dropped

significantly versus 1Q15, and although seasonal issues played a

role, secular

headwinds to growth are persistent.

These headwinds

Read more

BRIEF-Theraclion announces that a hospital based Italy has signed a commercial agreement for use of Echopulse system

* Announces that A.S.L. 6 Di Livorno, a public hospital

based in Tuscany, Italy, has signed a commercial agreement for

use of Echopulse system

Source text: http://bit.ly/29cOShA

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Sygnis says investor pledges to buy shares in capital hike

* Sygnis ag receives commitment for the purchase of up to

2.7 million shares within the scope of a capital increase to

finance the acquistion of Expedeon Holdings Ltd.

Source text for Eikon:

Further company coverage:

(Reporting by Frankfurt Newsroom)

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BRIEF-UK's CMA says not refer Mckesson unit, AAH Pharma-UDG deal for phase 2 probe

* UK's CMA says decided not to refer merger by Mckesson Corp unit AAH Pharmaceuticals of

MASTA and Sangers to a Phase 2 investigation.

Source text for Eikon: (http://bit.ly/29eSv3J)

(Bengaluru Newsroom)

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UPDATE 1-U.S. lifts "too big to fail" designation of GE's financing unit

June 29 (Reuters) - Lender GE Capital is no longer "too big

to fail" - the U.S. government on Wednesday removed its

"systemically important" designation, a label born of the

financial crisis given to institutions with the potential to

wreck the economy in the event of distress.

Read more

BRIEF-Kitov Pharmaceuticals announces pricing of $12 mln follow-on public offering

* Kitov pharmaceuticals announces pricing of $12 million

follow-on public offering in the U.S.A.

Read more

FDA asks for more data on over-the-counter hand sanitizers

June 29 (Reuters) - The U.S. Food and Drug Administration

said it is requesting additional data to support the safety and

effectiveness of certain active ingredients used in topical

consumer antiseptic rubs, including hand sanitizers, that are

sold over-the-counter.

Read more

U.S. lifts "too big to fail" designation of GE's financing unit

WASHINGTON, June 29 (Reuters) - Lender GE Capital on

Wednesday became the first firm to lose its designation as

"systemically important," a label born of the financial crisis

that the U.S. government gives to institutions with potential to

wreck the economy in the event of distress.

Read more

BRIEF-GE Capital cancels status as "systemically important"

* GE Capital receives approval for rescission of status as

systemically important financial institution

Read more

BRIEF-Serodus completes private placement

* Offered 9.7 million shares raising gross proceed of 10 million Norwegian crowns ($1.19

million)

Source text for Eikon:

Further company coverage:

($1 = 8.4265 Norwegian crowns)

(Gdynia Newsroom)

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UPDATE 1-Tesaro's ovarian cancer drug shows benefit in late-stage trial

June 29 (Reuters) - Tesaro Inc said its ovarian

cancer drug met the main goal of prolonging survival in

patients, without the disease worsening, in a late-stage trial,

sending its shares up 84 percent in premarket trading.

Read more

BRIEF-Tasly Pharma's Hong Kong unit plans convertible bonds, sees capital boost

* Says it plans to boost Hong Kong unit's capital by $15

million

Read more

BRIEF-NatureWise Biotech & Medicals gets patent in India

* Says it got patent for cinamic compounds and derivatives

therefrom for the inhibition of histone deacetylase in India

Read more

BRIEF-Zhuhai Hokai Medical Instruments' unit plans buyout fund with partners

* Says unit plans to set up buyout fund with partners worth

1 billion yuan ($150.40 million)

Read more

BRIEF-Biosearch's probiotic strain registered in China

* Says its probiotic strain Lactobacillus fermentum CECT5716

LC40 has been registered in China

Read more

BRIEF-NNIT signs new client in life sciences segment

* Signed a five-year, medium-size double-digit million Danish crown agreement with Ambu

on outsourcing company's IT infrastructure to NNIT

Source text for Eikon:

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BRIEF-Inner Mongolia Furui Medical Science gets approval to list French unit in Hong Kong

June 29 (Reuters) - Inner Mongolia Furui Medical Science Co

Ltd

Read more

BRIEF-Biotie Therapies appoints new CEO and CFO

* Timo Veromaa, President and CEO, David Cook, CFO and Stephen Bandak, CMO of Biotie are

leaving company by June 30, 2016

Read more

BRIEF-Pangen Biotech signs contract worth 600 mln won

* Says it signs contract with SAM CHUN DANG PHARM CO. LTD,

to provide protein

Read more

Tuesday, June 28, 2016

BRIEF-Techno Medica receives approval to extend submitting of annual report for FY 2016

* Says it has received the approval to extend the deadline

of submitting the annual report for fiscal year ended March 31,

2016 to July 29, instead of June 30

Read more

BRIEF-Zhejiang Hisun Pharmaceutical gets nod for clinic trial

June 29 (Reuters) - Zhejiang Hisun Pharmaceutical Co., Ltd.

:

Read more

BRIEF-Tego Science issues 1 bln won worth convertible bonds

* Says it completes the issuance of its second convertible

bonds as of June 29

Read more

BRIEF-Kangmei Pharmaceutical completes private placement of 8.1 bln yuan

* Says it completes the issue of 530,104,709 A shares at

15.28 yuan per share, for 8.1 billion yuan via private placement

Read more

BRIEF-Hybio Pharmaceutical gets patent license

* Says it received a patent license for synthesis method of

lisinopril

Read more

California gets go-ahead to vote on legalization of marijuana

June 28 (Reuters) - Californians are set to decide whether

to make recreational marijuana use legal, as other Western

states have done, after the California Secretary of State's

office said on Tuesday the issue could be put to voters in the

November ballot.

Read more

BRIEF-ILYANG PHARMACEUTICAL announces patent granted

* Says it receives a patent on June 28, for novel peptides

and use thereof

Read more

BRIEF-Solasto starts listing on TES first section and announces change in shareholding structure

* Says the company started listing on the Tokyo Stock

Exchange(TSE) first section, effective June 29

Read more

UPDATE 3-McKesson's IT unit to merge with Change Healthcare

* Companies will take steps to launch IPO after deal closes

(Adds Breakingviews link)

Read more

UPDATE 2-U.S. panel backs claim Lilly diabetes drug cuts cardiac death

June 28 (Reuters) - Eli Lilly & Co and Boehringer

Ingelheim should be allowed to claim that their diabetes drug

Jardiance cuts the risk of cardiovascular death, an advisory

panel to the U.S. Food and Drug Administration concluded on

Tuesday.

Read more

BRIEF-Hudson Executive Capital dissolves stake in Heartware International as of June 27

* Hudson Executive Capital LP dissolves stake in Heartware

International as of June 27 - SEC filing

Read more

BRIEF-Trividia initiates recall of certain lots of TRUEread, TRUEbalance, TRUEtrack & TRUEtest blood glucose test strips

* Trividia Health Inc initiates voluntary recall of certain

lots of TRUEread, TRUEbalance, TRUEtrack & TRUEtest blood

glucose test strips

Read more

BRIEF-Hemostemix says Criterium notified it has terminated master services agreement

* Criterium notified co it has terminated master services

agreement dated June 7, 2014 relating to clinical research

services

Read more

U.S. FDA panel backs claim Lilly diabetes drug

June 28 (Reuters) - Eli Lilly & Co and Boehringer

Ingelheim should be allowed to claim that their diabetes drug

Jardiance cuts the risk of cardiovascular death, an advisory

panel to the U.S. Food and Drug Administration concluded on

Tuesday.

Read more

BRIEF-Moody's - Medtronic's Heartware deal and dividend increase are credit negative

* Medtronic's Heartware deal and dividend increase are

credit negative

Source text for Eikon:

(Bengaluru Newsroom: +1 646 223 8780)

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BRIEF-U.S. FDA says continues to find benefits of flumist quadrivalent outweigh any potential risks

* FDA continues to find that the benefits of flumist

quadrivalent outweigh any potential risks

Read more

UPDATE 1-Brazil's Hypermarcas sinks as former executive admits bribery

SAO PAULO/BRASILIA, June 28 (Reuters) - Shares in

Hypermarcas SA, the largest Brazilian producer of generic drugs,

had their biggest intraday plunge in four years on Tuesday, on

reports that a former senior executive admitted paying bribes to

ruling coalition politicians.

Read more

BRIEF-Endo International announces issuance of Vasostrict patent

* Patent no. 9,375,478 has been submitted to FDA's Approved

Drug Products; to have submission date of June 28

Read more

UPDATE 2-Divided U.S. top court rejects family pharmacy's religious claim

WASHINGTON, June 28 (Reuters) - A divided U.S. Supreme Court

turned away an appeal by a family-owned pharmacy that cited

Christian beliefs in objecting to providing emergency

contraceptives to women under a Washington state rule, prompting

a searing dissent by conservative Justice Samuel Alito.

Read more

Funding to combat Zika fails to advance in U.S. Senate

WASHINGTON, June 28 (Reuters) - Funding to battle the Zika

virus failed to advance in the U.S. Senate on Tuesday, as

Democrats blocked a Republican proposal that they said would

short-change the challenge posed by the mosquito-borne virus as

well as other health priorities.

Read more

UPDATE 1-Gilead wins U.S. nod for drug for all types of hepatitis C

June 28 (Reuters) - U.S. health regulators on Tuesday

approved a combination drug by Gilead Sciences Inc that

is the first available treatment for all six major forms of

hepatitis C, advancing the company's leadership in the field and

sending its shares up almost 4 percent.

Read more

BRIEF-Welsh Carson Anderson & Stowe X LP dissolves stake in Universal American

* Welsh Carson Anderson & Stowe X Lp Dissolves Stake In

Universal American Corp As Of June 27 - Sec filing

Read more

CORRECTED-Zika vaccines prove 100 percent protective in mice; monkey study shows promise

CHICAGO, June 28 (Reuters) - Mice given a single shot of one of two experimental Zika vaccines were completely protected when exposed to the virus one to two months later, a promising sign that similar vaccines under development for humans will protect against Zika, U.S. researchers said on Tuesday.

Read more

BRIEF-Ab-Biotics to run a capital hike of up to 5 million euros

* To run a capital hike of up to 5 million euros ($5.5

million) issuing 3.1 million new shares at 1.60 euro per share

(0.05 euro nominal value plus share premium)

Read more

BRIEF-Monsanto and Nomad Bioscience announce collaboration on gene-editing research

* Monsanto and Nomad Bioscience announce collaboration on

gene-editing research for next-generation agriculture solutions

Read more

BRIEF-Pharmstandard recommends to approve mandatory tender offer from Augment Investments

* Says board recommends to approve mandatory tender offer

from Augment Investments

Source text: http://bit.ly/28ZH6To

Read more

BRIEF-Auris Medical completes enrollment of Phase 3 TACTT3 trial

* Auris Medical completes enrollment of Phase 3 TACTT3 trial

with Keyzilen in acute and post-acute inner ear tinnitus

Read more

BRIEF-Celyad says study has not succeeded - conference call

* Says with p-value witnessed optimistic that a partner will

take this further in the U.S. - conf call

Read more

BRIEF-Anthem says not in talks with Cigna Corp to end merger - StreetInsider, citing Bloomberg

* Anthem says not in talks with Cigna Corp to end merger -

StreetInsider, citing Bloomberg

Source text : (http://bit.ly/2914pNH)

(Bengaluru Newsroom: +1 646 223 8780)

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NEWSMAKER-China's Fosun looks for UK, Europe opportunities after Brexit vote - chmn

* And is looking to reduce its debts

(Adds quotes, detail, background)

Read more

BRIEF-Ok Biotech says 2015 dividend record date is July 24

* Says it will pay cash dividend of T$1.55 per share for

2015

Read more

Deals of the day- Mergers and acquisitions

June 28 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1000 GMT on Tuesday:

Read more

BRIEF-Canopy Growth Corp, Bedrocan Canada launch Brazil joint venture

* Canopy Growth Corporation and Bedrocan Canada launch

Brazil joint venture

Read more

BRIEF-Vivoline Medical elects Magnus Nilsson Chairman

June 28 (Reuters) - Vivoline Medical AB :



* Elects Magnus Nilsson Chairman

Source text for Eikon:



Further company coverage:

(Gdynia Newsroom)



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BRIEF-Apex Medical to pay 2015 dividend on Aug. 26

* Says it will pay cash dividend of T$1 per share

(T$83,385,557 in total) for 2015

Read more

BRIEF-UK's CMA says not to recommend McKesson-Bupa Home deal to in-depth investigation

* Decided not to recommend McKesson Corp deal with Bupa Home

Healthcare to a phase 2 investigation

Source text: http://bit.ly/292ycrB

Further company coverage:

(Bengaluru Newsroom)

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BRIEF-Winning Health Technology sees H1 profit up sharply on business expansion

* Says it expects H1 profit to rise about 619-644 percent

y/y to 420.5-435.1 million yuan ($63.24-$65.44 million)

Read more

BRIEF-Ando Health to provide 650 mln yuan loan guarantee for units

* Says the co will provide loan guarantee of 650 million

yuan in total for wholly owned units Andon Holdings Co., Ltd

(BVI) and iHealth Labs Europe

Read more

BRIEF-Jilin Zixin Pharmaceutical Industrial appoints chairman, general manager and CFO

June 28 (Reuters) - Jilin Zixin Pharmaceutical Industrial Co

Ltd :

Read more

BRIEF-Japan Lifeline to merge wholly owned unit JUNKEN MEDICAL Co Ltd

* Says it will merge a wholly owned unit JUNKEN MEDICAL Co

Ltd on Jan. 1, 2017

Read more

BRIEF-Nipro to repurchase 5 mln shares for 5 bln yen

* Says it will repurchase up to 5 million shares of its

common stock, representing a 2.9 percent stake from June 29 to

Dec. 28

Read more

Monday, June 27, 2016

BRIEF-DBV Technologies completes recruitment global phase III study of viaskin peanut

* Announces on Monday the completion of recruitment in

global phase III study of viaskin peanut for the treatment of

peanut allergic children

Read more

BRIEF-UMN Pharma signs basic agreement with Protein Sciences

* Says it signed basic agreement with Protein Sciences

Corporation regarding vaccine development for zika virus

infection

Read more

BRIEF-Xencor enteres into collaboration and license agreement with Novartis

* Xencor announces strategic collaboration for bispecific

programs, including XMAB 14045 and XMAB 13676

Read more

BRIEF-Wilex granted a patent in Europe for the chemical synthesis of dihydroxyisoleucine

* European patent office grants patent for chemical

synthetic building block dihydroxyisoleucine for production of

Amanitin

Read more

BRIEF-Yung Zip Chemical Ind says Lee Fang Yu resigns from chairman

June 28 (Reuters) - Yung Zip Chemical Ind :



* Says Lee Fang Yu resigned from chairman of the board



Source text in Chinese: http://985.so/4aRc



Further company coverage:

(Beijing Headline News)



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BRIEF-Andon Health plans to acquire eDevice via share private placement

* Says it plans to raise up to 710 million yuan ($106.80

million) in private placement of shares to fund acquisition of

eDevice

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Court decision shifts abortion battle to state bans

June 27 (Reuters) - The battle over abortion was expected to

shift to measures focusing on the fetus in the wake of the U.S.

Supreme Court's decision striking down a Texas law enacted in

the name of maternal health.

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UPDATE 1-Mayne Pharma nears deal for Teva assets -source

June 27 (Reuters) - Australia's Mayne Pharma Group Ltd

on Tuesday said it will acquire U.S. generic products

from Teva Pharmaceuticals for $652 million, helping it

propel into the top 2 in the general oral contraceptives market

in the United States.

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FEATURE-Japan revamps child welfare, but tens of thousands still institutionalised

TOKYO, June 28 (Reuters) - A baby lies in a metal-bar cot

drinking from a bottle perched on his pillow in a Tokyo

orphanage. There's no one to hold and feed him or offer words of

comfort.

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UPDATE 1-GE Capital to sell bulk of U.S. restaurant franchise loan portfolio

June 27 (Reuters) - General Electric Co said it would

sell a bulk of GE Capital's U.S. restaurant franchise loan

portfolio to three regional banks in separate deals as the

industrial conglomerate winds down its financing arm to reduce

regulatory burden.

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CORRECTED-Researchers may have found second 'superbug' gene in U.S. patient

CHICAGO, June 27 (Reuters) - Scientists may have identified

a second patient in the United States infected with bacteria

carrying the mcr-1 "superbug" gene, which makes bacteria highly

resistant to a last-resort class of antibiotics.

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BRIEF -MediBic cancels business alliance with FOUR SIS & CO

* Says it cancels business alliance with Tokyo-based wedding

dress maker FOUR SIS & CO, which was formed on May 28, 2015

Read more

BRIEF-Anhui Anke Biotechnology Group buys Wuxi-based co

* Says it acquired 100 percent stake in a Wuxi-based

biotechnology co

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Sunday, June 26, 2016

French and Benelux stocks-Factors to watch on June 27

PARIS, June 27 (Reuters) - Below are company-related news

and stories from French and Benelux media which could have an

impact on the region's markets or individual stocks.

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BRIEF-Nicox added to Russell Global Index

* Nicox added to Russell Global Index

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BRIEF-Zhejiang Hisoar Pharmaceutical to buy stake in Hunan-based co for 105 mln yuan

* Says it to buy 25 percent stake in a Hunan-based new

material co from two individuals and a Hengyang-based limited

partnership

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BRIEF-Tego Science to issue convertible bonds worth 1 bln won

* Says it will issue the second unregistered/unsecured

private convertible bonds, raising 1 billion won in proceeds

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UPDATE 1-Fresenius promotes CFO Sturm to CEO job after Schneider quits

BERLIN, June 26 (Reuters) - German healthcare group

Fresenius SE has appointed finance chief Stephan Sturm

as its new chief executive to replace long-serving boss Ulf Mark

Schneider, who quadrupled sales during his 13 years in charge.

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BRIEF-Medicinova added to Russell 3000  Index and Russell Global Index

* Company has been added to Russell 3000  Index and Russell

Global Index as a result of annual Russell Index reconstitution

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Fresenius promotes CFO Sturm to CEO job after Schneider quits

BERLIN, June 26 (Reuters) - German healthcare group

Fresenius SE has appointed finance chief Stephan Sturm

as its new chief executive, saying on Sunday that long-serving

boss Ulf Mark Schneider is leaving to pursue other

opportunities.

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TIMELINE-Milestones in legal fight over Texas abortion law

June 26 (Reuters) - The U.S. Supreme Court is set to rule on

Monday on a legal challenge by abortion providers to a Texas law

requiring doctors performing the procedure to have "admitting

privileges" at local hospitals and clinics to meet

hospital-grade standards.

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BRIEF-Beijing Science Sun Pharmaceutical says fund to sell 16.2 mln shares of it

* Says a fund will sell 16.2 million shares (6.75 percent

stake) of it in six months

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U.S. Supreme Court poised to issue major abortion ruling

WASHINGTON, June 26 (Reuters) - The U.S. Supreme Court is

due on Monday to issue its first major abortion ruling since

2007 against a backdrop of unremitting divisions among Americans

on the issue and a decades-long decline in the rate at which

women terminate pregnancies.

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UPDATE 1-China tightens controls on paid-for internet search ads

BEIJING, June 25 (Reuters) - China's internet regulator said

on Saturday that search engines should tighten management of

paid-for ads in search results, making clear which results are

paid-for and limiting their numbers.

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Friday, June 24, 2016

China tightens controls on paid-for internet search ads

BEIJING, June 25 (Reuters) - China's internet regulator said

on Saturday that search engines should tighten management of

paid-for ads in search results, making clear which results are

paid-for and limiting their numbers.

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Arizona says it has run out of drugs for executions

June 24 (Reuters) - Arizona has run out of execution drugs,

including a sedative implicated in botched lethal injections,

according to a filing on Friday in a court case challenging the

U.S. state's execution methods.

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Olympics-Golfer Grace pulls out of Olympics due to Zika

June 24 (Reuters) - South African Branden Grace joined a growing list of leading golfers withdrawing from the Rio Olympics on Friday due to concerns about the Zika virus.

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BRIEF-Frejoy Investment Management reports 9.2 pct passive stake in Sorrento Therapeutics

* Frejoy Investment Management Co Ltd reports 9.2 percent

passive stake in Sorrento Therapeutics Inc as of june 7, 2016 -

SEC filing

Source text: http://1.usa.gov/28TiETY

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BRIEF-Aetna, Humana delivered written notice to each other to extend "end date" with respect to merger from June 30-Dec 31

* Co, Humana delivered written notice to each other to

extend "end date" with respect to merger from June 30, 2016 to

Dec 31, 2016 - sec filing

Source text: http://1.usa.gov/28SE5YM

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BRIEF-Achaogen received second draw of $10 mln on June 20

* On June 20, received second draw in amount of $10.0

million contemplated by terms of a loan and security agreement

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BRIEF-Global Blood Therapeutics closes of public offering of common stock

* Says public offering of 6.40 million common shares priced

at $18.75 per share

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UPDATE 1-Rio doping lab's credentials suspended ahead of Olympics

SAO PAULO, June 24 (Reuters) - The World Anti-Doping Agency

(WADA) has suspended the credentials of a testing laboratory in

Rio de Janeiro that didn't conform with international standards,

just over a month before the city hosts the Olympic Games.

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UPDATE 1-UK 'Leave' vote deflates hopes for U.S.-EU trade deal

WASHINGTON, June 24 (Reuters) - Britain's looming exit from

the European Union is another huge setback for negotiations on a

massive U.S.-EU free trade deal that were already stalled by

deeply entrenched differences and growing anti-trade sentiment

on both sides of the Atlantic.

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Glass Lewis urges Medivation shareholders to support current board

June 24 (Reuters) - Medivation Inc said shareholder

advisory firm Glass Lewis & Co has recommended the cancer drug

maker's stockholders to not support Sanofi SA's

efforts to replace the company's board members.

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UK "Leave" a final nail in the coffin for stalled U.S.-EU trade deal

WASHINGTON, June 24 (Reuters) - Britain's looming exit from

the European Union is another huge setback for negotiations on a

massive U.S.-EU free trade deal that were already stalled by

deeply entrenched differences and growing anti-trade sentiment

on both continents.

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BRIEF-Pfizer completes acquisition of Anacor

* Continues to expect transaction to be slightly dilutive to

adjusted diluted earnings per share in 2017

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BRIEF-Kitov Pharmaceuticals reports new data demonstrating KIT-302 has beneficial effects on kidney function

* reports new data demonstrating KIT-302 has beneficial

effects on kidney function

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BRIEF-Immuron announces e-commerce agreement with QBID in China

* Travelan and protectyn will be covered by

marketing/distribution agreement, with products to be made

available from 1 june

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BRIEF-Great Basin Scientific receives positive Nasdaq listing determination

* Great Basin receives positive Nasdaq listing determination

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UPDATE 1-U.S. FDA panel to vote whether diabetes drug cuts cardiac death

June 24 (Reuters) - An advisory panel to the U.S. Food and

Drug Administration will be asked to vote next week on whether a

diabetes drug made by Eli Lilly & Co and Boehringer

Ingelheim cuts the risk of cardiovascular death, according to

documents posted on the agency's website on Friday.

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BRIEF-Joben Bio - Medical gets patent in U.S

* Says it got patent for extract of adlay bran and uses

thereof in U.S

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UPDATE 2-FACTBOX-Business reaction to Britain's decision to leave the EU

LONDON, June 24 (Reuters) - Britain's vote to leave the

European Union means uncertainty for markets and companies as

London initiates at least two years of negotiations with the EU.

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BRIEF-Chunghwa Chemical Symthesis & Biotech to pay 2015 dividend on Aug. 15

* Says it will pay cash dividend of T$1.5 per share

(T$116,340,000 in total) for 2015

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REFILE-To IPO or not to IPO: 2016 to remain tepid as investors stay away (June 22)

June 22 (Reuters) - Last fall, Jessica Mah, the founder and

chief executive of San Francisco-based inDinero, was deluged

with calls from investors wanting to know when the accounting

software maker would go public.

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BRIEF-Sichuan Kelun Pharmaceutical issues 500 mln yuan 2016 second tranche short-term financing notes

* Says it issues 500 million yuan 2016 second tranche

short-term financing notes, with coupon rate of 3.4 percent and

maturity date of March 17, 2017

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BRIEF-Sosei Group says appoints Peter Bains as CEO

* Shinichi tamura, sosei founder and group chairman,

president, ceo, appointed as representative executive officer

and executive chairman

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BRIEF-Glaxosmithkline says though the eu referendum result creates uncertainty and potentially complexity ... It does not currently anticipate a material adverse impact on the business, group's results or financial position

* Glaxosmithkline says though the eu referendum result

creates uncertainty and potentially complexity ... It does not

currently anticipate a material adverse impact on the business,

group's results or financial position

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BRIEF-Novartis, Roche say too early to predict impact of Brexit vote

* Roche Holding Ag says key priority is to ensure

that UK environment continues to support scientific innovation

and speedy access of innovative medicines for patients

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BRIEF-Hainan Shuangcheng Pharmaceuticals lowers 2016 H1 net loss outlook

June 24 (Reuters) - Hainan Shuangcheng Pharmaceuticals Co

Ltd :

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BRIEF-Medy-Tox to acquire properties for 82 bln won

* Says it will acquire land and building located in Seoul,

from MIRAE ASSET Life Insurance CO., Ltd.

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BRIEF-Mithra Pharmaceuticals signs LOI for estetrol with Fuji Pharmaceuticals

* Signs a Letter of Intent with Fuji Pharmaceuticals to work

towards a broad partnership on Estetrol in women's health, in

multiple indications to be determined in common agreement

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German pharma lobby says EU drug regulator must leave London

FRANKFURT, June 24 (Reuters) - The association of Germany's

pharmaceuticals industry said the European Union's London-based

drugs regulator, the European Medicines Agency, will have to

relocate after Britain's vote to leave the EU, posing a

considerable administrative burden for drugmakers.

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Thursday, June 23, 2016

Swiss stocks - Factors to watch on June 24

ZURICH, June 24 (Reuters) - The Swiss blue-chip SMI

was seen opening 7.9 percent lower at 7,388 points on Friday,

according to premarket indications from bank Julius Baer

.

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BRIEF-Zhejiang Jianfeng Group to pay 2015 div on June 30

* Says it will pay cash dividend of 1.8 yuan per 10 shares

(before tax) to shareholders for 2015 as a record of June 29

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BRIEF-Andon Health raises 924.2 mln yuan via private placement

* Says it issues 60.8 million shares and raises about 924.2

million yuan via private placement

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Singapore May factory output +0.9 pct y/y; -0.4 pct m/m

SINGAPORE, June 24 (Reuters) - Singapore's industrial

production in May grew from a year earlier, helped by increases

in pharmaceuticals and electronics output, data showed on

Friday.

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BRIEF-Hybio Pharmaceutical receives patent license

* Says it receives a patent license (No. ZL 2014 1

0196509.8), for the manufacturing method of a nesiritide

medicine

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BRIEF-Shandong Jincheng Pharmaceutical signs strategic cooperation agreement with partners

June 24 (Reuters) - Shandong Jincheng Pharmaceutical Co.,

Ltd. :

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BRIEF-Guangzhou Wondfo Biotech gets CE authentications

* Says it gets two CE authentications for its products,

Finecare FIA Meter Plus and Handheld Colloidal Gold Test

Analyzer

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BRIEF-Ningbo Medicalsystem Biotechnology to invest 20 mln yuan to set up unit

June 24 (Reuters) - Ningbo Medicalsystem Biotechnology Co.,

Ltd. :

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REFILE-UPDATE 1-Dodd, Frank blast ruling that MetLife not too big to fail

June 23 (Reuters) - A federal court's striking down of the

government's designation of insurer MetLife Inc as

"too-big-to-fail" could undermine efforts to head off another

financial crisis, authors of the landmark Dodd-Frank Wall Street

reform law said.

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BRIEF-Janssen Inc says Health Canada has approved Simponi for treatment of adults with severe active non-radiographic Axial Spondyloarthritis

* Health canada has approved Simponi for treatment of adults

with severe active non-radiographic Axial Spondyloarthritis

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WRAPUP-White House threatens to veto Republicans' Zika funding plan

WASHINGTON, June 23 (Reuters) - The White House on Thursday

threatened to veto the $1.1 billion approved by the U.S. House

of Representatives to fight the Zika virus, blasting the measure

for short-changing the administration's $1.9 billion funding

request.

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BRIEF-Oxford Immunotec enters into definitive agreement to acquire Imugen

* Deal for $22.2 million in an all cash transaction expected

to close on July 1, 2016

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Arkansas Supreme Court upholds lethal injection protocols

LITTLE ROCK, Ark., June 23 (Reuters) - The Arkansas Supreme

Court on Thursday upheld execution protocols regarding lethal

injection drugs, moving the state that has not held an execution

in more than a decade closer to resuming capital punishment.

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BRIEF-Cyclacel Pharmaceuticals may issue, sell shares having aggregate offering price of up to $4 mln through FBR

* Sales agreement with FBR Capital Markets & Co; may issue,

sell shares having aggregate offering price of up to $4 million

through FBR

Source text: http://1.usa.gov/28Qcw2y

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

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UPDATE 2- U.S. spurns AstraZeneca's nasal spray flu vaccine as ineffective

LONDON/CHICAGO, June 23 (Reuters) - U.S. health officials

have advised doctors not to use AstraZeneca's FluMist in

the upcoming flu season based on three years of U.S. data

showing that the nasal spray vaccine is not effective at

preventing influenza.

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UPDATE 1-California insurance commissioner urges DOJ to block Aetna-Humana deal

NEW YORK, June 23 (Reuters) - California Insurance

Commissioner Dave Jones on Thursday urged national antitrust

regulators to block health insurer Aetna Inc's proposed

$34 billion acquisition of Humana Inc.

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Third of hospitals in developing world lack clean running water - study

LONDON, June 23 (Thomson Reuters Foundation) - At least a

third of hospitals in developing nations do not have clean

running water, a study has found, leading to unsanitary

conditions and further spread of disease in drought-hit areas.

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BRIEF-Medtech announces 6 new ROSA sales

* Announces Six new ROSA robots sales: 2 in the U.S., 2 in

China, 1 in England and 1 in France

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BRIEF-Carmat begins CE Certification process for its artificial heart

* Carmat has begun, with Dekra, the ce certification process

for its bioprosthetic artificial heart

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BRIEF-Boston Biomedical announces first orphan drug designation for Napabucasin in gastric/gej cancer

* Boston Biomedical announces first orphan drug designation

for Napabucasin in gastric/gej cancer

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BRIEF-Supersonic Imagine announces completion patient enrollment in liver fibrosis clinical study

* Supersonic imagine announces the completion of patient

enrollment for pivotal liver fibrosis clinical study in China

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BRIEF-Visiomed Group signs distribution deal in the US for BewellConnect

* Signs major distribution agreement in the U.S. for

BewellConnect

Source text: http://bit.ly/28UNIFF

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German chemical industry union agrees 5.3 percent pay rise

FRANKFURT, June 23 (Reuters) - Germany's chemical industry

trade union IG-BCE and employers agreed a wage increase of 5.3

percent on Thursday, to be carried out over two steps.

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GAVI alliance offers matched funds for GSK malaria vaccine pilot

LONDON, June 23 (Reuters) - The GAVI global vaccine alliance

has offered funding of up to $27.5 million for pilot tests of

GlaxoSmithKline's first-generation malaria vaccine, but

only if other organisations promise to match that commitment.

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BRIEF-Wellcare Health expands Medicaid benefits in Georgia

* Wellcare expands Medicaid benefits in Georgia to promote

preventive care

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BRIEF-Atara Bio receives ATMP classification for its EBV-CTLs product candidate from EMA

* Atara Bio receives advanced therapy medicinal product

classification for allogeneic epstein-barr virus specific

cytotoxic T-Lymphocytes (EBV-CTLs) from European Medicines

Agency (EMA)

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BRIEF-Mateon announces initiation of focus study in platinum-resistant ovarian cancer

* Announces initiation of focus study in platinum resistant

ovarian cancer

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BRIEF-Teva settles patent litigation with AstraZeneca

* Teva settles patent litigation with AstraZeneca allowing

Teva to commercialize its generic version of Byetta (Exenatide

injection) in the United States

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BRIEF-Apellis announces results from Phase 1 complement C3 inhibitor trials

* Apellis Announces Positive Results From Phase 1 clinical

Trials Of Apl 2, a C3 complement inhibitor

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BRIEF-Immunovaccine awarded subcontract to evaluate depovax for development of malaria vaccine targets

* Awarded a subcontract by leidos to evaluate

immunovaccine's depovax(tm) platform for development of peptide

based malaria vaccine targets

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BRIEF-PExA AB sells PExA 2.0 to Uppsala University

Source text: http://bit.ly/28RTU2g



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BRIEF-Lock-up period for Grand Automotive Services' 446 mln shares to end

* Says lock-up period for 446 million shares to end, shares

to start trading on June 29

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BRIEF-Retrophin announces new data from physician-initiated treatment with RE-024

* Retrophin announces new data from physician-initiated

treatment with RE-024 at the 20th international congress of

Parkinson's disease and movement disorders

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Germany embraces glitzy offices to shake up corporate culture

MUNICH/HERZOGENAURACH, Germany, June 23 (Reuters) - Major

German companies are investing in ambitious new buildings

designed to attract top staff and encourage innovation, seeking

to create a more dynamic corporate culture and keep pace with

U.S. rivals despite investor concerns about the cost.

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UPDATE 1-AstraZeneca takes $80 mln hit as U.S. spurns nasal flu vaccine

LONDON, June 23 (Reuters) - AstraZeneca said it

would take an $80 million writedown on stocks of its flu vaccine

Flumist Quadrivalent, which is sprayed into the nose, after U.S.

health authorities decided they would not use the product.

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BRIEF-Pharmswell Bio appoints Jang Yeong Jin as co-CEO

* Says Choo Yeon Wu still serves as co-CEO of the company as

well

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BRIEF-Visgeneer says 2015 dividend record date is July 18

* Says it will pay cash dividend of T$7,142,125 in total for

2015

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BRIEF-SciBase insources production of electrodes from Ginolis

* Says production of disposable electrodes for SciBase's device Nevisense will be brought

in-house

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BRIEF-Shionogi & Co Ltd adjusts conversion price of 2019 due Euro Yen - denominated convertible bonds with warrants to 4,167.5 yen

* Says it adjusts conversion price of 2019 due Euro Yen -

denominated convertible bonds with warrants to 4,167.5 yen from

4,177.6 yen, effective from April 1

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Wednesday, June 22, 2016

BRIEF-Agfa HealthCare collaborates with IBM and Watson

* Reported on Wednesday that Agfa HealthCare collaborates

with IBM and Watson to advance Cognitive Imaging

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BRIEF-Neovacs raises 8 million euros in capital increase

* Said on Wednesday it raised 8 million euros ($9.1 million)

in capital increase

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UPDATE 1-U.S. Republican lawmakers to push $1.1 bln in new Zika funds

WASHINGTON, June 22 (Reuters) - Republicans in the U.S.

House of Representatives and Senate agreed on Wednesday to $1.1

billion to fight the Zika virus, a House Republican lawmaker

said, shortchanging President Barack Obama's funding request and

angering Democrats by making other cuts to pay for it.

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BRIEF-Jiangxi Fushine Pharmaceutical's CFO Chen Xiangqiang resigns

* Says Chen Xiangqiang resigned from the position of CFO of

the co

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BRIEF-Menicon repurchases shares at 2.84 bln yen

* Says it repurchased 925,311 shares of its common stock,

representing a 5.05 percent stake

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U.S. Senate Democratic leader dismisses Republicans' Zika funding proposal

WASHINGTON, June 22 (Reuters) - U.S. Senate Democratic

leader Harry Reid said an agreement announced on Wednesday by

House of Representatives Republicans on $1.1 billion in new

funding to fight the Zika virus was not a serious response to

the threat.

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BRIEF-Chongqing Taiji Industry Group units to invest 35 mln yuan to set up drug firm

* Says its three units will invest a combined of 35 million

yuan to set up a drug firm in Hainan

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U.S. congressional Republicans agree on $1.1 bln in new Zika funds

WASHINGTON, June 22 (Reuters) - Republicans in the U.S.

House of Representatives and Senate agreed on Wednesday to $1.1

billion in new funding to fight the Zika virus, a key House

Republican lawmaker said.

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BRIEF-Aurinia announces closing of US$7 mln private placement

* Aurinia announces closing of US$7 million private

placement

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Nose job: smells are smart sensors' last frontier

SINGAPORE, June 23 (Reuters) - Phones or watches may be

smart enough to detect sound, light, motion, touch, direction,

acceleration and even the weather, but they can't smell.

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Mateen altered looks, researched anti-psychotic drugs before attack -acquaintance

PORT ST. LUCIE, Fla., June 22 (Reuters) - On the morning

before the massacre at Orlando's Pulse gay nightclub, shooter

Omar Mateen drastically altered his appearance, shaving his head

and face, and seemed agitated and surly, said an acquaintance

who saw him that day.

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Zika fears sent Latin American women seeking abortion alternatives -study

CHICAGO, June 22 (Reuters) - Fearing the effects of the Zika virus on their unborn children, pregnant women in Latin America increasingly have sought out abortion pills online from a nonprofit aid agency, a new study has found.

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BRIEF-Cascadian Therapeutics to sell shares of Series D convertible preferred stock

* Intends to sell shares of Series D convertible preferred

stock having an aggregate value of up to $13.8 million

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BRIEF-Eiger Biopharmaceuticals CFO Welch buys 2500 shares of common stock at avg price of $19.79/shr - SEC filing

* CFO James Welch reports purchase of 2500 shares of

company's common stock at average price of $19.79 per share -

SEC filing

Source text - http://1.usa.gov/28QGX7q

Further company coverage:

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BRIEF-Grupo Ferrer buys 19.5 mln shares of Alexza Pharmaceuticals

* Grupo Ferrer Internacional, S.A. reports purchase of 19.5

mln shares of Alexza Pharmaceuticals on June 21 - SEC filing

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UPDATE 1-U.S. House Republicans unveil healthcare alternative to Obamacare

WASHINGTON, June 22 (Reuters) - Republicans in the U.S.

House of Representatives unveiled an alternative plan to

overhaul the nation's healthcare system on Wednesday, slamming

Obamacare even as they aimed to keep some of its more popular

provisions.

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BRIEF-Epizyme initiates collaboration on combination trial of tazemetostat and tecentriq for treatment of Non-Hodgkin Lymphoma

* Epizyme initiates collaboration on combination trial of

tazemetostat and tecentriq(tm)(atezolizumab) for treatment of

Non-Hodgkin Lymphoma

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Sex trafficking victims may push rescue away, U.S. experts say

BILLINGS, Montana, June 21 (Thomson Reuters Foundation) -

R ick and Pat Freeland have cared for hundreds of troubled girls

and women at their log cabin refuge deep in the Rocky Mountains,

but there's one rule; they will only take two victims of sex

trafficking at a time.

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BRIEF-Pharmstandard majority shareholders to buy out company shares at RUB 1,028/shr - Interfax

* Augment Investments has sent an obligatory tender offer to

the Central Bank of Russia for the purchase of Pharmstandard

shares at 1,028 roubles ($15.97) per share, Interfax

cites company statement

Further company coverage:

($1 = 64.3726 roubles)

(Gdynia Newsroom)

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BRIEF-Japan's Fujifilm says signed patent licensing agreement with China's Zhejiang Hisun Pharmaceutical involving drug Avigan- Nikkei

* Japan's Fujifilm has signed patent licensing agreement

with china's Zhejiang Hisun Pharmaceutical involving drug

Avigan,used to treat ebola - Nikkei

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BRIEF-Sphera Funds Management reports 7.6 pct passive stake in Vistagen Therapeutics as of May 11, 2016

* Sphera Funds Management Ltd reports 7.6 percent passive

stake in Vistagen Therapeutics Inc as of May 11, 2016 - Sec

filing

Source - http://1.usa.gov/28PKYsC

(Bengaluru Newsroom; +1 646 223 8780)

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BRIEF-Analogic says resolves distributor inquiry

* Reached agreements with sec, department of justice, and

danish government resolving previously disclosed fcpa

investigation

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BRIEF-Nightingale board concludes sale of assets comprising substantially all Canadian business

* Has been in discussions with potential acquirers with

intention of concluding a definitive agreement in respect of a

transaction

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India to revise drugs law, draft new rules for medical devices

MUMBAI, June 22 (Reuters) - India is working on revising its

drugs law to make it easier for companies to do business and to

improve the safety and efficacy of locally produced drugs, the

government said on Wednesday.

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BRIEF-A1M Pharma to use European CRO partner for preclinical toxicology studies

* Says has signed an agreement with Research Toxicology Centre, European contract research

organization, as CRO partner for the company's preclinical toxicology studies

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BRIEF-Karyopharm says initiates phase 1 clinical trial with KPT-9274

* Says first-In-Human, multi-center, open-label,

dose-escalation trial is expected to enroll up to 175 patients

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Bayer, Dupont join ag-tech investment boom to ease grain pain

* Latest companies to back tech startups as farm profits

shrink

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Coloplast cuts growth forecast due to emerging markets challenges

COPENHAGEN, June 22 (Reuters) - Danish healthcare products

maker Coloplast on Wednesday adjusted its growth

forecast downwards due to a challenging macroeconomic

environment in emerging markets.

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BRIEF-Adcare Health says New Beginnings Care becomes debtor in possession

* New beginnings care, llc became a debtor in possession in

a series of bankruptcy cases jointly administered under new

beginnings care, llc, et al., bankr. e.d. Tn chattanooga

division

Read more

BRIEF-Universal American says sale of traditional insurance business to close in Q3, 2016

* Sale of traditional insurance business to nassau

reinsurance group holdings, l.p. Is expected to close in q3 of

2016

Read more

BRIEF-Jiangsu Yuyue Medical Equipment and Supply raises 2.56 bln yuan via private placement

June 22 (Reuters) - Jiangsu Yuyue Medical Equipment and

Supply Co Ltd :

Read more

BRIEF-FIT Biotech: Tekes issues claim to partly reclaim capital loan

* Says Finnish Funding Agency for Innovation (Tekes) issues claim to partly reclaim capital

loan related to Fit Biotech HIV vaccine project in 2009-2010

Read more

BRIEF-Ambu acquires patented single-use airway tubes with integrated camera

* Ambu has signed a conditional agreement to acquire

Israeli-based ETView Medical Ltd

Read more

BRIEF-Recipharm announces global serialisation collaboration

* Says has

formed a global partnership with Marchesini, SEA Vision and

TraceLink to introduce new serialisation capabilities

Source text for Eikon:

Further company coverage:

(Stockholm Newsroom)

Read more

BRIEF-Brighter buys remaining shares in company behind jDome BikeAround

* Acquires remaining shares in company behind jDome

BikeAround

Source text for Eikon:

Read more

BRIEF-Brighter carries out set-off issue

* Carries out set-off issue of 4.2 million new shares to repay loan received in April 2016

Read more

Tuesday, June 21, 2016

BRIEF-Beijing Beilu Pharmaceutical to pay 2015 dividend on June 28

* Says it will pay cash dividend of 0.2 yuan per 10 shares

(before tax) to shareholders of record on June 27 for 2015

Read more

U.S. House Speaker Ryan unveils Republican alternative to Obamacare

WASHINGTON, June 22 (Reuters) - U.S. House of

Representatives Speaker Paul Ryan unveiled a Republican

healthcare agenda on Wednesday that would repeal Obamacare but

keep some of its more popular provisions.

Read more

BRIEF-Ma Kuang Healthcare Holding says 2015 stock dividend record date is July 20

* Says it will pay stock dividend of T$34,679,700 in total

for 2015

Read more

BRIEF-Harbin Gloria Pharmaceuticals updates pharma subsidiary sale to Shanxi C&Y

* Says it signed a new agreement to sell pharma subsidiary

to Shanxi C&Y, for 3.1 billion yuan

Read more

BRIEF-Alteogen announces patent granted

* Says it receives a patent on May 31, for modified antibody

in which motif comprising cysteine residue is bound, modified

antibody-drug conjugate comprising the modified antibody, and

production

Read more

BRIEF-ILDONG PHARMACEUTICAL announces patent granted

* Says it receives a patent on June 22, for micro

encapsulation of spore-forming probiotics removed an autolysin

and spore-forming probiotics prepared thereby

Read more

BRIEF-CAREGEN signs 9.53 bln won contract with CREATIO

* Says it signs a contract with CREATIO Corporation, to

supply hair products

Read more

BRIEF-Universal American announces pricing of $100 mln private offering of convertible senior notes and stock repurchase

* Announces pricing of $100 million private offering of

convertible senior notes and stock repurchase

Read more

PRESS DIGEST- British Business - June 22

June 22 (Reuters) - The following are the top stories on the

business pages of British newspapers. Reuters has not verified

these stories and does not vouch for their accuracy.

Read more

Argentina's YPF partners with GE to build generating plant

BUENOS AIRES, June 21 (Reuters) - Argentina's state oil

company YPF said on Tuesday it was partnering with

General Electric to build a $170 million generating plant

in the northern province of Tucuman.

Read more

BRIEF-Valeant Pharmaceuticals appoints Sam Eldessouky chief accounting officer

June 21 (Reuters) - Valeant Pharmaceuticals International

Inc :

Read more

BRIEF-Vivus receives notice from Hetero USA that it has filed with U.S. FDA ANDA for generic versions of all strengths of Stendra tablets

* Received notice from Hetero USA that it has filed with

U.S. FDA ANDA for generic versions of all strengths of Stendra

tablets

Read more

BRIEF-Eli Lilly Canada says Health Canada approves Taltz for treatment of moderate-to-severe plaque psoriasis

* Eli Lilly Canada says Health Canada has granted approval

for Taltz for treatment of moderate-to-severe plaque psoriasis

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom; +1 646 223 8780; )

Read more

BRIEF-MiMedx Group reaches settlement with Medline Industries and Liventa Bioscience for certain claims

* MiMedx reaches settlement with Medline Industries and

Liventa Bioscience for certain claims

Read more

BRIEF-Biostage CEO provides mid-year update to shareholders

* Now have capital to get through a number of milestones in

2016 including filing of IND; expect to move into human clinical

trials in 2017

Read more

BRIEF-Redhill Biopharma announces positive final results with endpoints in phase 1 study with Yeliva

* Redhill Biopharma announces positive final results with

primary and secondary endpoints met in phase 1 study with

Yeliva in advanced solid tumors

Read more

UPDATE 2-Impax buys generic drugs from Teva, Allergan for $586 mln

June 21 (Reuters) - Impax Laboratories Inc said it

would buy a portfolio of generic drugs from Teva Pharmaceutical

Industries Ltd and Allergan Plc for about $586

million.

Read more

Hedge fund Visium's Valvani found dead in apparent suicide: police

June 21 (Reuters) - Sanjay Valvani, a hedge fund manager at

Visium Asset Management LP who was arrested last week on insider

trading charges, has been found dead in an apparent suicide, the

police said on Tuesday.

Read more

BRIEF-LifeAssays Q2 sales shows same positive trend as in Q1

* Sales in Q2 have shown same positive trend as in Q1

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Euris gets second order for its new patient-oriented veterinary diagnostic systems

* Says has received second order for its new patient-oriented veterinary diagnostic systems

from the newly appointed distributor in Lithuania

Read more

BRIEF-Perrigo Company launches non-GMO infant formulas

* Perrigo announces FDA clearance and launch of non-GMO

infant formulas for the U.S. Store brand market

Read more

BRIEF-Progenics Pharmaceuticals signs commercial license agreement with Selexis SA

* Under agreement, progenics will have use of Selexis CHO-M

cell line and sure technology platform

Read more

BRIEF-Redhill Biopharma says Yeliva met main goal in early-stage study in solid tumors

* Redhill biopharma announces positive final results with

primary and secondary endpoints met in phase 1 study with

yeliva in advanced solid tumors

Read more

BRIEF-Royal Philips acquires PathXL

* Philips expands its digital pathology solutions portfolio

with the acquisition of PathXL

Source text for Eikon:

Further company coverage:

Read more

Deals of the day- Mergers and acquisitions

June 21 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 0930 GMT on Tuesday:

Read more

BRIEF-Sernova announces non-brokered private placement

* Sernova announces non-brokered private placement

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

GE seeks to sell remaining Hyundai Capital stake - Hyundai Motor

SEOUL, June 21 (Reuters) - South Korean car maker Hyundai

Motor Co said on Tuesday General Electric

seeks to sell out of its 20 percent stake in their joint

venture, unlisted lender Hyundai Capital, to a third party.

Read more

BRIEF-1nkemia invests in startups to create synergy

* Says buys 10.5 percent stake for 150,000 euros ($170,000)

in Kowlco Consciumers (Abouit) and becomes reference laboratory

for Abouit

Read more

BRIEF-Harbin Gloria Pharmaceuticals scraps full acquisition plan for Qingdao pharmacy firm

* Says it scraps full acquisition plan for Qingdao pharmacy

firm

Read more

BRIEF-XVIVO Perfusion extends acceptance period for public offer on Vivoline Medical

* Extends acceptance period for public offer on Vivoline Medical

Read more

UPDATE 1-Philips buys Northern Irish medical imaging company

* CEO says deals shows company's new healthcare focus

(Updates after company spokesman says digital pathology sales

will be "several tens of millions" this year, rather than just

10 million, including the acquisition.)

Read more

BRIEF-Sichuan Swellfun appoints Ho Danny as CFO

June 21 (Reuters) - Sichuan Swellfun Co., Ltd:



* Says it appointed Ho Danny as CFO of the company



Source text in Chinese: http://me2.do/5FLMuHfc



Further company Coverage:

(Beijing Headline News)



Read more

Monday, June 20, 2016

Swiss stocks - Factors to watch on June 21

ZURICH, June 21 (Reuters) - The following are some of the

main factors expected to affect Swiss stocks on Tuesday.

Read more

BRIEF-Biocartis launches advanced EGFR Mutation Assay

* Launches advanced EGFR Mutation Assay detecting over 50

mutations

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Kunming Longjin Pharmaceutical to sell unit for 2 mln yuan

* Says it to sell its wholly owned Beijing-based

pharmaceutical technology development subsidiary to an

individual for 2 million yuan

Read more

BRIEF-Cawachi repurchases shares at about 1 bln yen

* Says it repurchased 383,900 shares of its common stock, at

the price of 999,972,400 yen in total, from June 1 to June 20

Read more

BRIEF-Theravance Biopharma highlights positive results from phase 3 fulfil study of closed triple announced by Glaxosmithkline, Innoviva

* Highlights positive top-line results from pivotal phase 3

fulfil study of closed triple announced by Glaxosmithkline,

Innoviva

Read more

BRIEF-Global Blood Therapeutics announces pricing of public offering of common stock

* Says public offering of 6.40 million common shares priced

at $18.75 per share

Read more

BRIEF-Immune Pharmaceuticals data shows that ceplene enhances response to anti PD-1 AND ANTI-PD-l1 immune checkpoint inhibitors

* New data shows that Ceplene enhances response to anti

pd-1 and anti-pd-l1 immune checkpoint inhibitors in lymphoma and

solid tumor models

Read more

BRIEF-Kite Pharma opens T-Cell therapy manufacturing facility

* Preparations on track to launch lead product candidate

KTE-C19 in 2017

Read more

BRIEF-Viking Therapeutics' equity distribution agreement with Maxim Group

* Equity distribution agreement with Maxim Group Llc where

co may offer, sell from time to time, through maxim up to 3.7

million shares

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Cellular Biomedicine Group announces resale of up to 5.1 mln shares of common stock for sale by selling stockholders

* Resale of up to 5.1 million shares of common stock for

sale by the selling stockholders - SEC filing

Source text: http://1.usa.gov/28JLGsV

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

Read more

BRIEF-Scynexis launches public offering of common stock and warrants

* Scynexis announces launch of public offering of common

stock and warrants

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-HTG Molecular appoints new vice president of North American capital sales

* HTG Molecular appoints new vice president of North

American capital sales for the HTG Edgeseq platform

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Fitch: Anthem block of Cigna Buy wouldn't likely hurt ratings

* Fitch: Anthem block of Cigna buy wouldn't likely hurt

ratings

Read more

BRIEF-Eli Lilly sets quarterly dividend of $0.51/shr

* Sets quarterly dividend of $0.51 per share

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Seres Therapeutics says to begin SER-262 Phase 1b study in mid-2016

* Seres Therapeutics presents new data at ASM Microbe 2016,

including characterization of SER-262, the rationally-designed,

fermented microbiome therapeutic candidate for primary

clostridium difficile infection

Read more

BRIEF-Ultragenyx appoints Karah Parschauer as executive vice president, general counsel

* Ultragenyx appoints Karah Parschauer as executive vice

president, general counsel

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Adaptimmune Therapeutics receives positive opinion

* Adaptimmune receives positive opinion for orphan drug

designation in the European Union for spear t-cell therapy

targeting NY-ESO for treatment of soft tissue sarcoma

Read more

BRIEF-Collegium Pharmaceutical commercially launches Xtampza ER

* Announced commercial launch of Xtampza er (oxycodone)

extended-release (ER) capsules in united states

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Oncternal receives fast track designation for TK216 in relapsed or refractory ewing sarcoma

* Oncternal receives fast track designation for TK216 in

relapsed or refractory ewing sarcoma

Read more

BRIEF-Mednax says announces acquisition of Anesthesiology practice in NY

* Mednax inc says no additional terms of transaction were

disclosed

Read more

BRIEF-Lock-up period for Shenqi Pharma's 302.1 million shares to end

June 20 (Reuters) - Shanghai Shenqi Pharmaceutical

Investment Management Co Ltd

Read more

UPDATE 1-India announces sweeping reforms to foreign direct investment rules

* Full foreign ownership allowed in defence, civil aviation

(New throughout with announcement)

Read more

India now most open economy in world for FDI - Modi

NEW DELHI, June 20 (Reuters) - Indian Prime Minister

Narendra Modi hailed a sweeping liberalisation of rules on

foreign direct investment on Monday, saying they would make

Asia's third-largest economy the most open in the world.

Read more

BRIEF-Daiichi Sankyo plans 28 mln shares repurchase

* Says it plans to buy 28 million shares (4.1 percent

outstanding) back, for up to 500 million yen, from June 21 to

Oct. 28

Read more

BRIEF-Kontigo Care: new share issue oversubscribed at 112 pct

* Overallotment option excercised to about 2.3 million Swedish crowns ($279,316)

Read more

CORRECTED-Circassia's cat allergy treatment fails late-stage trial

June 20 (Reuters) - Drug developer Circassia Pharmaceuticals

Plc said its cat allergy treatment failed to meet its

main goal in a late-stage study, due to a marked placebo effect.

Read more

BRIEF-Milestone Scientific ups votes in Milestone Medical to 98.1 pct

* Said on Friday that as a result of a share exchange agreement, Milestone Scientific Inc

has acquired 2,413,978 shares of Milestone Medical Inc

Read more

BRIEF-SEOUL PHARMA says conversion of convertible bonds worth 1.3 bln won

* Says 1.3 billion won worth of its second convertible bonds

have been converted into 92,425 shares of the company at 14,100

won per share

Read more

CORRECTED-German stocks - Factors to watch on June 20

FRANKFURT, June 20 (Reuters) - The DAX top-30 index

looked set to open 2.2 percent higher on Monday, according to

premarket data from brokerage Lang & Schwarz at 0600 GMT.

Read more

Sunday, June 19, 2016

Roche announces availability of LightMix modular Zika Virus Assay

ZURICH, June 20 (Reuters) - Swiss drugmaker Roche

said on Monday its LightMix Modular Zika Virus Assay (CE) is

available in markets accepting the CE mark for patients with

signs and symptoms of the Zika infection where the virus is

known to be present.

Read more

BRIEF-Paion reports positive remimazolam headline data in phase III study in procedural sedation for colonoscopy

* Said on Sunday remimazolam met its primary efficacy

endpoint in the first study of its pivotal U.S. Phase III

program in patients undergoing procedural sedation

Read more

Swiss stocks - Factors to watch on June 20

ZURICH, June 20 (Reuters) - Here are some of the main

factors that may affect Swiss stocks on Monday:

Read more

BRIEF-Shanghai Shyndec Pharmaceutical to pay 2015 dividend on June 24

June 20 (Reuters) - Shanghai Shyndec Pharmaceutical Co Ltd

:

Read more

BRIEF-Jinyu Bio-Technology to pay 2015 dividend on June 24

* Says it will use undistributed profits to pay a cash

dividend of 4 yuan (pre-tax) per 10 shares to shareholders of

record on June 23 for 2015

Read more

PRESS DIGEST- Financial Times - June 20

June 20 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

Read more

Antitrust regulators worry about proposed Cigna-Anthem merger -WSJ

June 19 (Reuters) - U.S. antitrust regulators are concerned

about health insurer Anthem Inc's proposed acquisition

of Cigna Corp and not sure the companies can offer enough

concessions to maintain competition in the industry, the Wall

Street Journal reported on Sunday.

Read more

Immigration, abortion, race rulings due at U.S. Supreme Court

WASHINGTON, June 19 (Reuters) - The U.S. Supreme Court is

heading into its home stretch, with major rulings due by the end

of the month on President Barack Obama's unilateral immigration

plan, racial preferences in university admissions and a

restrictive Texas abortion law.

Read more

BRIEF-Joben Bio-Medical gets patent in China

* Says it got patent for a kind of nerve protective

composition and its application in China

Read more

BRIEF-Hunan Jingfeng Pharmaceutical to pay 2015 dividend on June 23

* Says it will pay a cash dividend of 1 yuan (before tax)

per 10 shares and use additional paid-in capital to distribute 1

new shares for every 10 shares, to shareholders of record on

June 22 for 2015

Read more

BRIEF-Joben Bio-Medical gets patent in U.S

* Says it got patent for use of alcohol extract of longan

seeds in U.S

Read more

BRIEF-Joben Bio-Medical gets patent in Taiwan

* Says it got patent for authentication method of Cinnamomum

kanehirae in Taiwan

Read more

Hologic wins emergency U.S. authorization for Zika test

June 17 (Reuters) - Hologic Inc won emergency U.S.

authorization to sell its Zika test, expanding the number of

public and private labs that can test for the virus as health

officials brace for a rise this summer in the number of

infections.

Read more

Friday, June 17, 2016

BRIEF-FDA grants emergency use authorization for Hologic's Aptima zika virus assay

* FDA grants emergency use authorization for Hologic's

Aptima zika virus assay

Read more

BRIEF-Cellectar Biosciences files for resale of 300,006 shares

* Files for resale of 300,006 shares of common stock offered

by selling stockholders - SEC filing

Source text - http://1.usa.gov/1Xus1yR

Further company coverage:

Read more

BRIEF-Zosano Pharma says appointed Georgia Erbez as interim CFO

* Appointed Georgia Erbez as interim chief financial officer

of company

Read more

BRIEF-Neogenomics files for stock shelf of up to $200 mln

* Files for stock shelf of up to $200 million - SEC filing

Source text -http://1.usa.gov/24WtPQB

Further company coverage:

Read more

BRIEF-Fedex says concluded internet pharmacy case

* Fedex announces successful conclusion of internet pharmacy

case

Read more

Kosovo minister quits following health bribery probe

PRISTINA, June 17 (Reuters) - Kosovo's environment minister

resigned on Friday after a prosecutor filed charges against him

for allegedly channelling illegal payments to private hospitals

while he was health minister in the previous government.

Read more

As rate hike worries fades, M&A bond issuers hold off

NEW YORK, June 17 (IFR) - After weeks of hectic issuance,

the US primary high-grade market is set to slow as companies

slam the brakes on jumbo bond sales to finance mergers and

acquisitions until the autumn.

Read more

BRIEF-Ariad Pharmaceuticals completes strategic review, reaffirms 2016 outlook

* Outcomes of strategic review includes significant

reduction in company's expense base

Read more

BRIEF-AtriCure files for mixed shelf offering of up to $150 mln

* Atricure Inc files for secondary stock shelf offering of

up to $115.2 million

Read more

BRIEF-Crossject delays filing of marketing authorization for Zénéo Adrenaline

* Due to a delay in bioequivalence study led by its customer, filing of marketing

authorization for Zénéo Adrenaline should be delayed several months as well

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Abivax says primary endpoint of ABX203 Phase IIb/III trial unlikely to be reached

* Analysis of ongoing ABX203 Phase IIb/III trial in chronic Hepatitis B virus infection

shows good safety, but primary endpoint of study is unlikely to be reached

Read more

South African "virgin bursaries" scheme ruled unconstitutional

JOHANNESBURG, June 17 (Reuters) - A controversial scheme

offering university scholarships to young South African women

who remain virgins is unconstitutional, the Commission for

Gender Equality ruled on Friday.

Read more

RPT-South African "virgin bursaries" scheme ruled unconstitutional

JOHANNESBURG, June 17 (Reuters) - A controversial scheme

offering university scholarships to young South African women

who remain virgins is unconstitutional, the Commission for

Gender Equality ruled on Friday.

Read more

BRIEF-BrainCool: Receives proceeds of about SEK 14.5 mln through share issue

* Company receives proceeds of 14.5 million Swedish crowns ($1.74 million) before issue

costs of 800,000 crowns

Read more

BRIEF-Oxigene announces name change to Mateon Therapeutics

* Announced that it has changed its name to Mateon

Therapeutics, Inc., effective immediately

Read more

BRIEF-Ginwa Enterprise adjusts private placement, to raise up to 963.3 mln yuan

* Says it adjusts private placement plan, to raise up to

963.3 million yuan ($146.19 million)

Read more

BRIEF-Zosano Pharma enrolls first subject in migraine treatment trial

June 17 (Reuters) - Zosano Pharma Enrolls First Subject In

Pivotal Clinical Trial For Zp

Read more

BRIEF-Ariad initiates submission of NDA for Brigatinib to FDA ahead of plan

* Rolling NDA submission is expected to be complete in Q3 of

2016.

Read more

UPDATE 1-WHO backs plan to cut yellow vaccine dose to eke out supplies

* One-fifth vaccine dose expected to protect for at least 1

year

(Adds details on vaccine supply, yellow fever outbreaks)

Read more

WHO says $122 million needed for global response to Zika virus

LONDON, June 17 (Reuters) - Almost $122 million is needed to

prevent and manage the medical complications of the Zika virus

spreading throughout the Americas and causing birth defects in

babies, the World Health Organization said on Friday.

Read more

BRIEF-Guangdong Zhongsheng Pharmaceutical signs cooperation agreement with WuXi AppTec

June 17 (Reuters) - Guangdong Zhongsheng Pharmaceutical Co

Ltd :

Read more

Lifting U.S. curbs on gay blood donors seen years away -experts

NEW YORK/WASHINGTON, June 17 (Reuters) - U.S. health

regulators are under increasing pressure to remove restrictions

keeping most gay and bisexual men from donating blood, but

experts say any change would require years of research to

guarantee the safety of the blood supply.

Read more

BRIEF-Guangdong Biolight Meditech to buy 20 pct stake in minimally invasive medical device company at 20 mln yuan

* Says it will buy 20 percent stake in a Changzhou-based

minimally invasive medical device company at 20 million yuan

Read more

UPDATE 2-Singapore May exports post surprise jump on gold, drugs shipments

* NODX to China -10.1 pct y/y, to Europe -14.0 pct y/y

(Adds comments and details on gold exports,)

Read more

BRIEF-Almirall's CFO, Daniel Martinez, steps down

* Says executive vice-president of finance (CFO), Daniel

Martinez, steps down

Read more

BRIEF-Olympus announces application of International Financial Reporting Standards

* Says it plans to apply International Financial Reporting

Standards (IFRS) as the new accounting method, to replace the

current Japan-Generally Accepted Accounting Principles

Read more

BRIEF-Vivoline Medical applies for delisting

* Applies for delisting from First North

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

Thursday, June 16, 2016

British companies prepare for long night to possible Brexit

LONDON, June 17 (Reuters) - British companies are preparing

for the possibility that the country will vote to leave the

European Union with extra funds, pre-written statements and

plans for late-night vigils by teams of consultants.

Read more

BRIEF-Swissmed Centrum Zdrowia Q4 2015/2016 net loss shrinks to 642,000 zlotys

* Q4 2015/2016 revenue 9.3 million zlotys ($2.4

million)versus 9.9 million zlotys a year ago

Read more

BRIEF-BioScrip prices 40 mln shares offering at $2.00 per share

* Says offering of 40.0 million common shares priced at

$2.00 per share

Read more

BRIEF-Innocoll Holdings prices 5.7 mln shares offering at $7.00 per share

* Says priced an underwritten public offering of 5.7 million

shares at $7.00 per share for aggregate gross proceeds of $40.1

million

Read more

BRIEF-Lansdowne Partners believes Grupo Ferrer's unit tender offer to buy alexza pharma's shares not fair

* Believe tender offer commenced by subsidiary of grupo

ferrer to buy alexza pharma's shares at $0.90per share neither

fair nor in best interests of stockholders

Read more

BRIEF-Spineguard receives US FDA clearance to market PediGuard

* Receives U.S. FDA clearance to market PediGuard Threaded

DSG device

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Biotime says public offering of 7.32 mln common shares priced at $2.39 per share

* Says public offering of 7.32 million common shares priced

at $2.39 per share

Read more

BRIEF-Oncosec Medical presents preliminary findings from head and neck phase II clinical trial

* Oncosec presents preliminary findings from head and neck

phase ii clinical trial at eurogin 2016 conference

Read more

Roche skin cancer drugs "too expensive", says UK cost agency

LONDON, June 16 (Reuters) - Roche's two-drug

combination of Cotellic and Zelboraf for melanoma was rejected

by Britain's healthcare cost agency NICE as "too expensive" on

Thursday, in contrast to the green light given in April to a

rival cocktail from Novartis.

Read more

U.S. top court sends healthcare fraud claim case back to lower court

WASHINGTON, June 16 (Reuters) - The U.S. Supreme Court on

Thursday threw out an appeals court ruling that went against

hospital operator Universal Health Services Inc over

whether it has to face a lawsuit accusing it of defrauding the

government in a case arising from a Massachusetts woman's death

at a mental health facility.

Read more

BRIEF-Pharmacolog gets financing from Vinnova for integrating DrugLog with clinical drug system

* Vinnova has granted the Karolinska University Hospital and Pharmacolog AB funds for a

joint development project for safer and more effective medication

Read more

Merck's Keytruda prolongs life in big lung-cancer study

June 16 (Reuters) - Advanced lung cancer patients who took

Merck & Co's Keytruda immuno-oncology medicine in a

large trial and were previously untreated went longer without

their disease worsening and showed a survival advantage over

those given standard chemotherapy, the drugmaker said on

Thursday.

Read more

BRIEF-Valeant says launches new Preservision AREDS 2 formula + multivitamin

June 16 (Reuters) - Valeant Pharmaceuticals International

Inc

Read more

BRIEF-Beleave appoints Dana Gidlow head of veteran affairs and community outreach

* Beleave appoints retired lieutenant colonel Dana Gidlow as

head of veteran affairs and community outreach

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Spectral Medical says FDA accepts pre-clinical PMA module for Toraymyxin(TM)

* Spectral Medical says FDA accepts pre-clinical PMA module

for Toraymyxin(tm)

Source text for Eikon:

Further company coverage:

Read more

BRIEF-Karyopharm completes enrollment in ongoing storm study; results expected mid-2016

* To report top-line data from phase 1b clinical trial of

selinexor in combination with some agents over next 18 months

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Amsurg says on termination of merger, co may be required to pay $180 mln to Envision

* On termination of merger agreement, under some

circumstances, co may be required to pay a termination fee of

$180 million to envision - sec filing

Read more

BRIEF-Aerie Pharma completes enrollment of phase 3 clinical trial of eye drug Rhopressa

* Trial on track for topline 90-day interim efficacy readout

in q4 2016

Read more

BRIEF-Sanochemia Pharmazeutika announces cooperation with b.e.imaging and SPL Medical B.V.

* Announces cooperation with b.e.imaging and SPL Medical

B.V.

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-TaiwanJ Pharmaceuticals to issue 20 mln new shares

* Says it will issue 20 million new shares of its common

stock with par value of T$10 per share and issue price at T$35

per share

Read more

BRIEF-Shanghai Runda Medical to acquire stake in Canada's Response Biomedical

* Says it plans to acquire about 43.1 percent stake in

Response Biomedical Corp for up to $6 million

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Spain's ACS close to selling Urbaser waste group -media

MADRID, June 16 (Reuters) - Spanish builder and service

provider ACS is close to finalising the sale of its

waste management business Urbaser to Chinese groups for more

than 2 billion euros ($2.3 bln), two newspapers reported on

Thursday.

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BRIEF-Epigenomics: Epi Procolon included in newly issued USPSTF guidelines for colorectal cancer screening

* Epi Procolon included in newly issued USPSTF guidelines

for colorectal cancer screening

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UPDATE 2-UK Stocks-Factors to watch on June 16

June 16 (Reuters) - Britain's FTSE 100 index is seen opening down 41

points, or 0.7 percent lower, on Thursday, according to financial bookmakers,

with futures down over 1 percent ahead of the cash market open. For more

on the factors affecting European stocks, please click on

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BRIEF-Caregen signs contract worth 874.4 mln won

* Says it signed contract with PALMED Health Products Trade

& Ltd. Co., to supply Prostrolane for osteoarthritis treatment

uses

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Wednesday, June 15, 2016

Swiss stocks - Factors to watch on June 16

ZURICH, June 16 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.9 percent lower at 7,612 points on Thursday,

according to premarket indications by bank Julius Baer

.

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BRIEF-Create Medic completes share buy back

* Says it bought back 300,000 shares from Feb. 15 to June

15, for 255,649,600 yen

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BRIEF-Fagron launches 88.2 million euro capital increase

* Capital increase with preferential subscription rights of

maximum 88,265,360.40 euros ($99.54 million) through issuance

of maximum 17,105,690 new shares at an issue price of 5.16 euros

per share

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UK Stocks-Factors to watch on June 16

June 16 (Reuters) - Britain's FTSE 100 index is seen opening down 41

points, or 0.7 percent lower, on Thursday, according to financial bookmakers.

For more on the factors affecting European stocks, please click on



* The UK blue chip index closed 0.7 percent higher at 5,966.80 points on

Wednesday, as a rally in metals prices following a weaker dollar boosted basic

resources stocks, although housebuilders came under pressure ahead of a vote on

the country's European Union membership.

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Fitch Rates Hua Han's USD Senior Notes Final 'BB-'

(The following statement was released by the rating agency)

HONG KONG/SHANGHAI, June 15 (Fitch) Fitch Ratings has assigned

Hua Han Health

Industry Holdings Limited's (Hua Han, BB-/Stable) USD150m 7.00%

senior notes due

16 June 2019 a final rating of 'BB-'.

The notes are rated at the same level as Hua Han' senior

unsecured rating

because they are regarded as direct and senior unsecured

obligations of the

company. The assignment of the final rating follows the receipt

of documents

conforming

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BRIEF-Lepu Medical Technology (Beijing) to pay 2015 dividend on June 23

June 16 (Reuters) - Lepu Medical Technology (Beijing) Co.,

Ltd. :

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BRIEF-Apeloa Pharmaceutical to pay 2015 dividend on June 21

* Says it will pay a cash dividend of 0.55 yuan (pre-tax)

for every 10 shares to shareholders of record on June 20 for

2015

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BRIEF-Da An Gene Co Ltd of Sun Yat-Sen University to pay 2015 dividend on June 21

June 16 (Reuters) - Da An Gene Co Ltd of Sun Yat-Sen

University :

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PRESS DIGEST- British Business - June 16

June 16 (Reuters) - The following are the top stories on the

business pages of British newspapers. Reuters has not verified

these stories and does not vouch for their accuracy.

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BRIEF-LabGenomics announces patent granted

* Says it receives a patent license on June 15, for

providing dielectric analysis related service and method thereof

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BRIEF-Aveo Pharmaceuticals says sale of 37.1 mln shares by stockholders

* Announces sale of 37.1 million shares of common stock by

selling stockholders - sec filing

Source text - (http://1.usa.gov/1VZX0ly)

Further company coverage:

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BRIEF-Envision Healthcare and AmSurg to merge

* Combined organization will have a pro forma market

capitalization of approximately $10 billion and enterprise value

of approximately $15 billion

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BRIEF-Corium International says initiated reduction in workforce

* On June 14, 2016, co approved and initiated a reduction in

its workforce of employees and contractors - SEC filing

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BRIEF-Odontoprev announces own capital interest payment

* Announced on Tuesday that its board approved, ad

referendum of the general meeting of shareholders, own capital

interest payment totalling gross 11.4 million Brazilian reais

($3.3 million), corresponding to 0.0216 real per share

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