Thursday, September 22, 2016

BRIEF-ArgenX provides update on lead programs in auto-immune disease and oncology at research and development day in New York

* ArgenX provides update on lead programs in auto-immune

disease and oncology at research and development day in New York

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Hill-Rom Holdings amends senior credit agreement

* Hill Rom holdings inc says on september 8, 2015, entered

into senior credit agreement

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BRIEF-Kleo Pharmaceuticals appoints David A. Spiegel as CEO

* Kleo Pharmaceuticals Inc. appoints David A. Spiegel as

chief executive officer

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BRIEF-Galmed Pharmaceuticals signed agreement with University of California

* Signed an investigator-initiated clinical trial agreement

with University of California, San Diego, school of medicine

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BRIEF-Vistagen Therapeutics provides business outlook

* Vistagen Therapeutics provides business outlook and sets

corporate milestones

Read more

BRIEF-Oncology Venture decides on SEK 22.5 mln rights issue

* Board decided to - subject to approval at Extraordinary General Meeting - conduct a rights

issue of up to 774,984 shares at an issue price of 29.00 Swedish crowns per share

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BRIEF-Allergan and Adamas announce all four dosage strengths of NAMZARIC available throughout U.S.

* Co and Adamas Pharmaceuticals announce all four dosage

strengths of NAMZARIC now available by prescription in

pharmacies throughout U.S.

Source text for Eikon:

Further company coverage:

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UPDATE 1-UK okays Alexion drug costing up to $2 mln but wants price cut

LONDON, Sept 22 (Reuters) - A new drug to treat a rare

inherited bone disorder that was developed by Alexion

Pharmaceuticals and could cost up to 1.5 million pounds

($2 million) a year per patient has been cleared for limited use

by Britain's health cost watchdog.

Read more

BRIEF-Navidea achieves $1 mln in Lymphoseek commercial milestones

* Navidea achieves $1 million in Lymphoseek commercial

milestones

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BRIEF-Antares Pharma completes QuickShot Testosterone clinical program

* Antares Pharma announces completion of the QuickShot

Testosterone clinical program

Source text for Eikon:

Further company coverage:

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BRIEF-OrganiGram's License Capacity Increased by Health Canada

* Health Canada also increased OrganiGram's licensed

production and sales capacity for cannabis oils to 500kg per

annum

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BRIEF-Egalet announces results after study of ARYMO ER extended-release tablets

* Announces results from a category 3 oral human abuse

potential study and a category 3 intranasal hap study of product

candidate ARYMO ER extended-release tablets

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BRIEF-Lumosa Therapeutics completes issuing new shares for T$556.4 mln

* Says it completed issuing 10 million new shares at T$54

per share with amount of T$556.4 million

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BRIEF-Medical and Surgical Centre reports 15 months ended June 2016 group pre-tax profit of 125.4 mln rupees

* 15 months ended June 2016 group profit before taxation of

125.4 million rupees

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BRIEF-Aurobindo Pharma gets USFDA tentative approval for Dolutegravir

* Aurobindo Pharma receives USFDA tentative approval for

Dolutegravir, allowing the product to be launched in the PEPFAR

market

Source text: (http://bit.ly/2cTnfIs)

Further company coverage:

(Bengaluru newsroom)

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BRIEF-Kleo Pharmaceuticals appoints David Spiegel as CEO

* Kleo Pharmaceuticals says Spiegel will also serve on

company's board of directors

Read more

Czech Republic - Factors To Watch on Sept 22

PRAGUE, Sept 22 (Reuters) - Here are news stories, press

reports and events to watch which may affect Czech financial

markets on Thursday.



ALL TIMES GMT (Czech Republic: GMT + 2 hours)

=========================ECONOMIC DATA==========================

Real-time economic data releases....................

Summary of economic data and forecasts...........

Recently released economic data..................

Previous stories on Czech data.............

**For

Read more

BRIEF-Kancera: research grant of about EUR 0.5 mln under EU's Horizon 2020

* Receives research grant of about 0.5 million euros ($561,100) within 3 years under frames

of EU's Horizon 2020 program

Read more

Wednesday, September 21, 2016

PRESS DIGEST - Wall Street Journal - Sept 22

Sept 22 (Reuters) - The following are the top stories in the

Wall Street Journal. Reuters has not verified these stories and

does not vouch for their accuracy.

Read more

PRESS DIGEST- New York Times business news - Sept 22

Sept 22 (Reuters) - The following are the top stories on the

New York Times business pages. Reuters has not verified these

stories and does not vouch for their accuracy.

Read more

REFILE-UPDATE 2-Chan Zuckerberg Initiative pledges $3 billion to fight disease

SAN FRANCISCO, Sept 21 (Reuters) - Facebook Chief Executive

Mark Zuckerberg and his wife Priscilla Chan on Wednesday pledged

more than $3 billion toward a plan to "cure, prevent or manage

all disease within our children's lifetime."

Read more

UPDATE 1-Novo Nordisk to supply insulin at discount to poorest nations

NEW YORK, Sept 21 (Reuters) - Danish drugmaker Novo Nordisk

A/S pledged on Wednesday to provide insulin at

steeply discounted prices in the world's least-developed nations

in what it is calling its "access to insulin commitment."

Read more

BRIEF-Gilead terminates phase 2/3 study of GS-5745 in patients with Ulcerative Colitis

* A phase 3 study of GS-5745 is ongoing in patients with

Gastric Cancer

Read more

UPDATE 2-U.S. lawmakers blast Mylan CEO over 'sickening' EpiPen price hikes

WASHINGTON, Sept 21 (Reuters) - U.S. lawmakers on Wednesday

blasted Mylan NV Chief Executive Heather Bresch for

sharply increasing prices for the EpiPen emergency allergy

treatment at a congressional hearing in which Republicans and

Democrats questioned the reasons behind rising U.S. drug costs.

Read more

Obesity, violence hamper U.S. progress on UN health goals - study

LONDON, Sept 21 (Reuters) - The United States performs

poorly in U.N. rankings on progress towards global health goals

due to its high levels of violence, alcohol abuse and childhood

obesity, a study has found.

Read more

BRIEF-Sanford reports a passive stake of 9.7 percent in Caladrius Biosciences

* Sanford reports a passive stake of 9.7 percent in

Caladrius Biosciences Inc as of Sept. 14 - SEC filing

Source text for Eikon:

Further company coverage:

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UnitedHealth trims drug coverage, including Sanofi insulin

Sept 21 (Reuters) - UnitedHealth Group Inc, the

largest U.S. health insurer, will stop covering several

brand-name drugs as of next year, reinforcing a trend of payers

steering prescriptions to lower-priced options.

Read more

UPDATE 1-Chan-Zuckerberg Initiative pledges $3 billion to curing, managing disease

SAN FRANCISCO, Sept 21 (Reuters) - Facebook Chief Executive

Mark Zuckerberg and his wife, Priscilla Chan, on Wednesday

pledged more than $3 billion toward a plan to "cure, prevent or

manage all disease within our children's lifetime."

Read more

Patients greeted by robot at Belgian hospital



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Chan-Zuckerberg Initiative pledges $3 bln to curing and managing disease

SAN FRANCISCO, Sept 21 (Reuters) - Facebook Chief Executive

Mark Zuckerberg and his wife Priscilla Chan on Wednesday pledged

more than $3 billion toward a plan to "cure, prevent or manage

all disease within our children's lifetime."

Read more

BRIEF-Mauna Kea technologies reports H1 2016 financial results

* H1 revenue 4.9 million euros ($5.47 million) versus 4.7 million euros year ago

Read more

BRIEF-Anthem and Cigna have accused one another of merger breach - Bloomberg

* Anthem and Cigna have accused one another of merger breach - Bloomberg

Source text - (http://bloom.bg/2cR9knM)

Further company coverage:

(Bengaluru Newsroom)

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BRIEF-Sensorion Initial results of phase 1b clinical study on SENS-111

* Initial Results Of Phase 1b Clinical Study On Sens-111

Presented At The AAO-HNSF Annual Meeting In San Diego

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BRIEF-My Size files for stock shelf of up to 2.23 mln shares

* Files for public offering of up to 2.23 million shares of

co's common stock by the selling stockholders - sec filing

Read more

Rift Valley Fever outbreak kills 21 in western Niger

DAKAR, Sept 21 (Thomson Reuters Foundation) - Health workers

in western Niger are racing to contain an outbreak of Rift

Valley fever that has killed at least 21 people over the past

month, an aid agency said on Wednesday.

Read more

Novo Nordisk to supply insulin at discount to poorest nations

NEW YORK, Sept 21 (Reuters) - Danish drugmaker Novo Nordisk

A/S on Wednesday pledged to provide insulin at

steeply discounted prices in the world's least-developed nations

in what it is calling its "access to insulin commitment."

Read more

BRIEF-BioMarin reviews status of Exon 51 composition of matter

* To seek review of patent trial and appeal board ruling,

for composition of matter claims related to exon 51 skipping

antisense oligonucleotides

Read more

BRIEF-BiondVax Phase 2b European Trial: Last Patient Out

* Last participant in a European phase 2b clinical trial of

M-001, its universal flu vaccine candidate, has completed final

visit

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BRIEF-Allergan says expects NASH market to reach $8 bln to $10 bln/year

Sept 21 (Reuters) - Allergan, in conference call with

analysts:

Read more

BRIEF-Sarepta Therapeutics says Edward Kaye appointed CEO, president

* Kaye will continue in his role as Chief Medical Officer

Source text http://bit.ly/2dj97eg

Further company coverage:

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BRIEF-Bluebird Bio's LentiGlobin investigational gene therapy accepted into Europen Medicines Agency's PRIME program

* LentiGlobin(TM) investigational gene therapy for

transfusion-dependent beta-thalassemia accepted into European

Medicines Agency's PRIME program

Source text for Eikon:

Further company coverage:

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BRIEF-Eleven Biotherapeutics buys Viventia Bio to create oncology company

* Eleven Biotherapeutics acquires Viventia Bio to create

targeted protein therapeutics oncology company

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BRIEF-Zhejiang Conba Pharmaceutical to issue 1.1 bln yuan 5-yr bonds

* Says to issue 1.1 billion yuan ($164.89 million) 5-year

bonds

Read more

BRIEF-Syngene International buys systems biology, pharma services practice of Strand Life Sciences

* Syngene International closes deal with Strand Life

Sciences to purchase systems biology and pharma services

practice

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BRIEF-Bio Gate H1 net income at around 0.1 mln euros

* In H1 an increase in sales of nearly 30 percent to more

than 2.0 million euros (py: 1.6 million euros)

Read more

BRIEF-Xiangxue Pharmaceutical unit to fully acquire food company at 1.8 mln yuan

* Says its subsidiary Guangzhou Asia Beverage Company

Limited will buy 100 percent stake in a Guangzhou-based food

company at 1.8 million yuan

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BRIEF-Cancer Genetics says it entered into partnership with Bio Analytical Research Corporation

* Announced today that it has entered into a partnership

with Bio Analytical Research Corporation

Read more

BRIEF-Xiangxue Pharmaceutical says investment company to invest 2.2 mln yuan in unit

* Says a Guangzhou-based investment company will invest 2.2

million yuan in its subsidiary Guangzhou Asia Beverage Company

Limited

Read more

German stocks - Factors to watch on September 21

FRANKFURT, Sept 21 (Reuters) - The DAX top-30 index

looked set to open 0.8 percent higher on Wednesday, according to

premarket data from brokerage Lang & Schwarz at 0620 GMT.

Read more

BRIEF-Malin Corp says investee company Novan completes IPO

* A Malin Corporation Plc investee company, Novan Inc today

successfully completed an initial public offering of its shares

Read more

Czech Republic - Factors To Watch on Sept 21

PRAGUE, Sept 21 (Reuters) - Here are news stories, press

reports and events to watch which may affect Czech financial

markets on Wednesday.



ALL TIMES GMT (Czech Republic: GMT + 2 hours)

=========================ECONOMIC DATA==========================

Real-time economic data releases....................

Summary of economic data and forecasts...........

Recently released economic data..................

Previous stories on Czech data.............

**For

Read more

Tuesday, September 20, 2016

BRIEF-Evotec, Bayer to develop new treatments to fight kidney diseases

* Says goal is development of multiple clinical candidates

for treatment of kidney diseases such as chronic kidney disease

in diabetes patients

Read more

BRIEF-Macrogen receives patent

* Says it receives patent Sept. 21, for fusion protein

comprising C-terminal domain of RET protein and use thereof as a

diagnosing marker

Read more

BRIEF-Walvax Biotechnology to sell entire stakes in Shandong Shijie Biological Technology

* Says to sell entire 85 percent stake in Shandong Shijie

Biological Technology Co Ltd for 697 million yuan ($104.46

million)

Read more

BRIEF-Beijing Leadman Biochemistry appoints Zhang Xinyu as finance director

Sept 21 (Reuters) - Beijing Leadman Biochemistry Co Ltd

:



* Says it appoints Zhang Xinyu as finance director



Source text in Chinese: https://goo.gl/sDYjFy



Further company Coverage:

(Beijing Headline News)



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BRIEF-Kolen receives patent

* Says it receives patent on Sept. 21, for photographic lens

optical system

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BRIEF-Anhui Anke Biotechnology Group to invest 30 mln yuan in biotechnology firm

* Says it to invest 30 million yuan in a Shanghai-based

biotechnology firm

Read more

BRIEF-Kolen receives patent

* Says it receives patent on Sept. 21, for voice Coil Motor

Auto focus module and Camera adopting the module

Read more

BRIEF-Novan announces pricing of 4.1 mln shares of common stock at a price of $11 per share

* Announces pricing of initial public offering of common

stock

Read more

PRESS DIGEST- Financial Times - Sept 21

Sept 21 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

Read more

BRIEF-Emad Rizk of Accuray tendered his resignation from the board

* On september 16, 2016, Emad Rizk tendered his resignation

from the board of directors - SEC filing

Read more

BRIEF-Monsanto Co - Bayer not required to take any material adverse divestiture action

* Bayer not required to take any divestiture action that

would likely result in 1-year loss of net sales to Bayer, co in

excess of $1.6 billion

Read more

BRIEF-Mast reports top-line results from phase 3 study in Sickle Cell Disease

* No statistically significant differences between treatment

groups in intent-to-treat population across 2 secondary efficacy

endpoints

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BRIEF-Fortress biotech enters into credit facility agreement with opus point healthcare innovations fund

* On Sept. 14, Co entered into a credit facility agreement

with Opus Point Healthcare Innovations Fund, Lp- SEC filing

Read more

BRIEF-Adamas announces results of Ease Lid 3

* Announces results of Ease Lid 3, a pivotal trial of ADS

5102 for the treatment of Levodopa-induced Dyskinesia (lid) in

parkinson's disease patients at the 4th world parkinson congress

Read more

U.S. Senate finance committee asks for Mylan EpiPen rebate investigation

NEW YORK, Sept 20 (Reuters) - The U.S. Senate Finance

Committee on Tuesday said it had asked the U.S. Department of

Health and Human Services to investigate the rebates to state

Medicaid programs for Mylan Inc's EpiPen treatment.

Read more

US STOCKS-Wall St buoyed by healthcare with Fed on deck

* Indexes up: Dow 0.26 pct, S&P 0.25 pct, Nasdaq 0.27 pct

(Updates to late afternoon)

Read more

BRIEF-PHM proposes separation into two new industry-leading public companies

* Co announced that its Board of directors has approved

plans to separate into two companies

Source text for Eikon:

Further company coverage:

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BRIEF-Vexim H1 net loss narrows to 2.5 million euros

* H1 net loss EUR 2.5 million ($2.79 million)versus loss of

EUR 3.6 million year ago

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BRIEF-Abivax H1 net loss widens to 8.3 million euros

* H1 net loss EUR 8.3 million ($9.27 million) versus loss of

EUR 7.2 million year ago

Read more

BRIEF-Enzo Biochem announces New York State Health Department approval of new cardiac assay

* Enzo Biochem announces New York State Health Department

approval of new easily adaptable, cost effective cardiac assay

Read more

UPDATE 1-West Virginia investigating Mylan over EpiPen pricing

NEW YORK, Sept 20 (Reuters) - The state of West Virginia is

investigating whether Mylan NV violated antitrust law or

defrauded the state's Medicaid program in connection with its

EpiPen device.

Read more

EU mergers and takeovers (Sept 20)

BRUSSELS, Sept 20 (Reuters) - The following are mergers

under review by the European Commission and a brief guide to the

EU merger process:

Read more

West Virginia investigating Mylan over EpiPen pricing

Sept 20 (Reuters) - The state of West Virginia is

investigating whether Mylan NV violated antitrust laws

or defrauded the state's Medicaid program in connection with its

EpiPen device.

Read more

BRIEF-Ampliphi Biosciences provides update on phase 1 trial in chronic rhinosinusitis patients

* Ampliphi Biosciences provides update on phase 1 trial in

chronic rhinosinusitis patients

Read more

NEWSMAKER-Breaking the mould: GSK picks Big Pharma's first female CEO

LONDON, Sept 20 (Reuters) - Emma Walmsley, GlaxoSmithKline's

incoming CEO, breaks the mould as the first woman to

lead a top global drugmaker and stands out among Big Pharma

bosses as a consumer brands guru rather than a prescription

medicines expert.

Read more

South Africa's Tutu responding well to treatment -family

CAPE TOWN, Sept 20 (Reuters) - South African anti-apartheid

activist and veteran cleric, Archbishop Desmond Tutu, was

responding well to a new course of antibiotics, his daughter

said on Tuesday, following social media reports her father had

died.

Read more

GRAPHIC-Credit Suisse sees scope for UK mining dividend rise

LONDON, Sept 20 (Reuters) - Dividend yields at British

mining companies have hit a five-year low just as cash flows in

the sector improve, prompting some analysts to call for higher

payouts as early as next year.

Read more

BRIEF-Can-Fite reports new data on CF102'S liver protective & regenerative properties published in scientific journal

* CF102 is currently in global phase II trial for liver

cancer and preparing for phase II trial in Nash

Read more

BRIEF-Lannett announces approval for Buprenorphine and Naloxone Sublingual Tablets

* Received approval from FDA of ANDA for Buprenorphine and

Naloxone Sublingual Tablets, 2 mg/0.5 mg and 8 mg/2 mg

Read more

BRIEF-Bellerophon therapeutics announces management transition

Sept 20 (Reuters) - Bellerophon Therapeutics Announces

Planned Management Transition by year end

Read more

Drugmakers pledge to clean up antibiotic factories, curb overuse

Sept 20 (Reuters) - Thirteen leading drugmakers promised on

Tuesday to clean up pollution from factories making antibiotics

and take steps to curb overuse of the medicines as part of a

drive to fight the rise of drug-resistant superbugs.

Read more

BRIEF-Lansen Pharmaceutical says unit entered into framework agreement with Natural Dailyheath

* Maximum value of transactions between parties contemplated

during term will be rmb80 million

Read more

CORRECTED-UPDATE 2-GlaxoSmithKline names insider Emma Walmsley as new CEO

LONDON, Sept 20 (Reuters) - GlaxoSmithKline said on

Tuesday it had chosen its head of consumer healthcare, Emma

Walmsley, as its new chief executive, after considering internal

and external candidates.

Read more

BRIEF-Chengdu Huasun's unit signs auto parts industrial park project worth 126.6 mln yuan

* Says unit signs auto parts industrial park project worth

126.6 million yuan ($18.98 million)

Read more

Monday, September 19, 2016

GlaxoSmithKline names consumer head Walmsley new CEO

LONDON, Sept 20 (Reuters) - GlaxoSmithKline said on

Tuesday it had chosen Emma Walmsley, head of consumer

healthcare, as its new chief executive, after considering

internal and external candidates.

Read more

BRIEF-Cantargia prepares intensified development strategy and capital raising

* Expands its initial clinical phase I/IIa study of CAN04 with combination therapies

Read more

BRIEF-Formycon H1 turnover down at 8.76 mln euros

* H1 turnover was 8.76 million euros ($9.79 million),

compared to 9.82 million euros in same period previous year

Read more

UK Stocks-Factors to watch on Sept. 20

Sept 20 (Reuters) - Britain's FTSE 100 index is seen opening 1 to 7

points lower, or down as much as 0.1 percent on Tuesday, according to financial

bookmakers.



* The UK blue chip index closed at 6,813.55 on Monday, up 103.27 points or

1.5 percent, thanks to a rise in commodity-related stocks.

* UNILEVER: Unilever said on Monday it would buy Seventh

Generation, a U.S.-based maker of "green" home and personal care goods, its

latest deal aimed at boosting the faster-growing part of it

Read more

BRIEF-Onco Therapy Science to start Phase I clinical study for breast cancer patients in U.S.

* Says the co will conduct Phase I clinical study of OTS167,

a MELK specific inhibitor, for breast cancer patients following

the acceptance of the protocol by the U.S. Food and Drug

Administration

Read more

Three private equity firms bid for GE's Hyundai Card stake - Invest Chosun

SEOUL, Sept 20 (Reuters) - Three private equity firms are

bidding for General Electric's 43 percent stake in its

South Korean credit card joint venture, Hyundai Card, in a deal

that may be worth more than 600 billion won ($537 million),

Invest Chosun reported on Tuesday.

Read more

BRIEF-Shire priced its public offering of $12.1 bln aggregate principal amount of senior notes

* Priced its inaugural public offering of $12.1 billion

aggregate principal amount of senior notes

Read more

BRIEF-Cirrus Logic set to join S&P Midcap;400 Amphastar to join S&P Smallcap 600

* Cirrus Logic set to join S&P Midcap 400; Amphastar

Pharmaceuticals to join S&P Smallcap 600

Source text for Eikon:

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PRESS DIGEST- Financial Times - Sept 20

Sept 20 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

Read more

BRIEF-FDA approves 6-month primary end point for the Lutonix

* Approves 6 Primary efficacy end point in clinical trial is

a composite of limb salvage and primary patency at 6 months

Read more

BRIEF-Moody's says expectations for Abbott's ratings unchanged

* Moody's says expectations for Abbott's ratings unchanged

following news of medical optics sale

Source text for Eikon:

Further company coverage:

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BRIEF-Response Biomedical receives court approval of going-private transaction

* Response Biomedical Corp receives court approval of

going-private transaction

Source text for Eikon:

Further company coverage:

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BRIEF-Kewaunee Scientific awarded $18.5 million contract in Kuwait

* Kewaunee Scientific awarded $18.5 million contract in

Kuwait

Source text for Eikon:

Further company coverage:

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BRIEF-Xencor inc files for mixed shelf of upto $300 million

* Files for mixed shelf of upto $300 million - SEC filing

Source text for Eikon:

Further company coverage:

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BRIEF-Arvida Group to acquire three villages for NZ$66 mln

* Acquisition immediately accretive to underlying earnings

with 6% lift in proforma FY17 EPS

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BRIEF-Remeditex Ventures LLC reports 6.6 pct passive stake in Venaxis

* Remeditex Ventures LLC reports 6.6 pct passive stake in

Venaxis as of September 12, 2016 - SEC Filing

Source - http://bit.ly/2cNHvcY

Further company coverage:

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BRIEF-Sarepta Therapeutics says U.S. Commercial launch for Exondys 51 planned to commence immediately

* Sarepta therapeutics announces fda accelerated approval of

exondys 51(tm) (eteplirsen) injection, an exon skipping therapy

to treat duchenne muscular dystrophy (dmd) patients amenable to

skipping exon 51

Read more

MOVES-Houlihan Lokey hires Taylor for healthcare group

NEW YORK, Sept 19 (IFR) - Boutique investment bank Houlihan

Lokey said it has hired Marshall Taylor as a managing director

and national healthcare leader in its transaction advisory

services group in Dallas.

Read more

BRIEF-Bpifrance grants Nanobiotix a 2 million euros interest-free loan to support final development stage of lead product, NBTXR3

* Bpifrance grants Nanobiotix a 2 million euros ($2.24

million) interest-free loan to support final development stage

of lead product, NBTXR3

Source text for Eikon:

Further company coverage:

($1 = 0.8948 euros)

(Gdynia Newsroom)

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BRIEF-James Flynn reports 9.79 pct stake in Adeptus Health

* James Flynn Reports 9.79 Pct Stake In Adeptus Health Inc

As Of September 16 - Sec filing

Read more

BRIEF-Invent Medic now sees to reach target of break-even in H1 2018

* Says multicenter study regarding Tension Free Vaginal Support (TVS) to

start in Q4 2016, which is one quarter later than planned

Read more

BRIEF-Mabvax Therapeutics provides interim progress on programs

* Mabvax therapeutics reports on interim progress on its

programs including the phase i clinical trial for therapeutic

antibody treatment of pancreatic cancer

Read more

BRIEF-Press Ganey Holdings announces end of go-shop period

* During go-shop period, cos representatives engaged in

solicitation of 26 potential strategic bidders and 50 potential

financial bidders

Read more

BRIEF-Cyxone: Patent approval in US

* Has received patent approved in US

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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Florida governor says no Zika transmission in Miami's Wynwood in 45 days

Sept 19 (Reuters) - Florida Governor Rick Scott on Monday

said there has been no local transmission of Zika in 45 days in

the Miami neighborhood of Wynwood, the first site of a

non-travel related case of the virus in the continental United

States.

Read more

BRIEF-Biotec Pharmacon confirms reimbursement in another region in Germany

* Receives confirmation of Woulgan being reimbursed by Statutory Health Insurance fund

(krankenkasse) in another region in Germeny

Read more

BRIEF-NuVasive receives FDA 510(k)clearance

* Receives FDA 510(k) clearance reinforcing comprehensive

portfolio supporting pediatric, adolescent and adult spinal

deformity patients

Source text for Eikon:

Further company coverage:

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BRIEF-PlexBio signs license agreement with Denka Seiken for $1 mln

* Says it signed a license agreement with Denka Seiken Co

Ltd to authorize its multiple detection technology platform and

product joint development agreement to Denka Seiken for $1

million

Read more

BRIEF-Active Biotech updates on laquinimod development

* Active Biotech update on laquinimod development: U.S, Food

and Drug Administration rescinds special protocol assessment for

laquinimod

Source text for Eikon:

Further company coverage:

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UPDATE 2-Eastern Aleppo aid stuck in Turkey as Syria truce ends

BEIRUT, Sept 19 (Reuters) - Two 20-truck aid convoys

destined for eastern Aleppo with enough supplies to feed 185,000

people for a month are still stuck in Turkey, a U.N. spokesman

said on Monday, hours after a ceasefire in Syria expired.

Read more

Study shines a light on low winter-time male libido

LONDON, Sept 19 (Reuters) - Exposure to bright light can

raise testosterone levels and lead to greater sexual

satisfaction in men with low sexual desire, according to the

results of a small scientific trial.

Read more

BRIEF-Zhongyuan Union Cell & Gene invests in stake in Genetron Health

Sept 19 (Reuters) - Zhongyuan Union Cell & Gene Engineering

Corp Ltd

Read more

BRIEF-Tonghua Dongbao Pharmaceutical to transfer ginseng tissue culture adventitious technological achievement to Dongbao Industry Group at 12.2 mln yuan

* Says it will transfer its ginseng tissue culture

adventitious technological achievement to Dongbao Industry Group

at 12.2 million yuan

Read more

BRIEF-Kontigo Care signs deal with Tranås municipality

* Receives order from Tranås municipality for delivery of Triplea system

Read more

UPDATE 2-UK Stocks-Factors to watch on Sept 19

Sept 19 (Reuters) - Britain's FTSE 100 index is seen opening up 68

points, or 1 percent, on Monday, according to financial bookmakers, with futures

up 0.94 percent ahead of the cash market open.

Read more

BRIEF-Guangdong Zhongsheng Pharmaceutical raises 1 bln yuan via private placement

Sept 19 (Reuters) - Guangdong Zhongsheng Pharmaceutical Co

Ltd :

Read more

Sunday, September 18, 2016

French and Benelux stocks-Factors to watch on Sept.19

PARIS, Sept 19 (Reuters) - Below are company-related news

and stories from French and Benelux media which could have an

impact on the region's markets or individual stocks.

Read more

Novartis says Entresto linked to higher quality of life scores

ZURICH, Sept 19 (Reuters) - Swiss drugmaker Novartis

said on Monday that a new analysis showed its Entresto

drug was linked to higher quality of life scores among patients

who had been hospitalized with reduced ejection fraction heart

failure.

Read more

Swiss stocks - Factors to watch on Sept 19

ZURICH, Sept 19 (Reuters) - The following are some of the

main factors expected to affect Swiss stocks on Monday:

Read more

IFR Capital Markets Week Ahead - September 19, 2016

LONDON, Sept 19 (IFR) - Welcome to the IFR Capital Markets

Week Ahead - a new weekly email newsletter from Thomson Reuters

IFR.

TAKING A HIKE

Corporate bond markets are expected to take a breather, with

most issuers set to sit out the next few days ahead of two big

central bank decisions on Wednesday. The US Federal Reserve

could shock markets with its second hike in a decade, while the

Bank of Japan is considering big changes to its mammoth

quantitative easing programme.

Read more

BRIEF-Zhejiang NHU's unit plans JV with Zhejiang Runtu

* Says co's special material unit plans to set up a joint

venture with Zhejiang Runtu Co Ltd

Read more

BRIEF-Zhejiang Hisoar Pharmaceutical raises 1.03 bln yuan via private placement

Sept 19 (Reuters) - Zhejiang Hisoar Pharmaceutical Co.,

Ltd. :

Read more

BRIEF-ST Pharm signs contract worth 151.94 bln won

* Says it signs contract with GSIUC, to provide Anti-viral

API

Read more

GE brings off-the-shelf biotech drug factories to Ireland

LONDON, Sept 19 (Reuters) - General Electric is

digging deeper into biotechnology with plans to build four

prefabricated drug factories in Ireland, bringing to Europe a

low-cost manufacturing concept it first pioneered in China.

Read more

UPDATE 4-Merkel's party suffers rout in Berlin in migrant policy backlash

* Rifts in conservative camp look set to deepen

(Adds details, quotes)

Read more

UPDATE 1-Novartis says MS drug cut risk of disability advance in study

ZURICH, Sept 17 (Reuters) - Novartis's

investigational multiple sclerosis drug cut the risk of

disability progression in patients with a tough-to-treat form of

the disease versus a placebo, the Swiss company said on

Saturday, citing a new analysis of a late-stage trial.

Read more

Saturday, September 17, 2016

Novartis says MS drug cut risk of disability advance in study

ZURICH, Sept 17 (Reuters) - Novartis's

investigational multiple sclerosis drug cut the risk of

disability progression in patients with a tough-to-treat form of

the disease versus a placebo, the Swiss company said on

Saturday, citing a new analysis of a late-stage trial.

Read more

UPDATE 2-17-year-old is first minor to be granted euthanasia in Belgium

BRUSSELS, Sept 17 (Reuters) - A 17-year-old has committed

doctor-assisted suicide in Belgium, the first minor to do so

under rules adopted in 2014 allowing euthanasia for people of

all ages, the head of the national committee for euthanasia said

on Saturday.

Read more

Belgium reports first case of euthanasia for a minor

BRUSSELS, Sept 17 (Reuters) - A minor has been euthanised in

Belgium in what is the first application of rules adopted by the

country in 2014 allowing doctor-assisted death for children of

all ages, the head of the national committee for euthanasia said

on Saturday.

Read more

South Africa's Tutu back in hospital after surgery

CAPE TOWN, Sept 17 (Reuters) - South African cleric and

anti-apartheid icon Desmond Tutu was readmitted to hospital on

Saturday to treat an infection following a surgery last week,

his family said.

Read more

Friday, September 16, 2016

BRIEF-Pfizer reports positive top-line results from reflections B537-02 study for PF-06438179

* Results confirm similar efficacy of PF-06438179

(Infliximab-pfizer) to Remicade(REG) (Infliximab), in

combination with Methotrexate

Read more

BRIEF-Tang Capital reports 9.5 pct stake in Cyclacel Pharmaceuticals

Source text - http://bit.ly/2cDs1vi

Further company coverage:

Read more

UPDATE 1-Perrigo explores sale of royalties of drug Tysabri -sources

Sept 16 (Reuters) - Perrigo Company Plc, the

manufacturer of generic drugs and over the counter medicines

targeted by activist investor Starboard Value LP, is exploring a

sale of the royalties from its multiple sclerosis drug Tysabri,

people familiar with the matter said.

Read more

BRIEF-Tenet enters into an amendment No. 1 to its existing letter of credit facility agreement

* Says on September 15, entered into an amendment no. 1 to

its existing letter of credit facility agreement

Read more

UPDATE 2-Abbott to sell its eye care business to J&J for about $4.33 bln

Sept 16 (Reuters) - Abbott Laboratories said it

would sell its eye care business to Johnson & Johnson

for about $4.33 billion in cash to focus on cardiovascular

devices and diagnostics business.

Read more

BRIEF-Sequenom announces tender offers, consent solicitations for 5 pct convertible senior notes

* Labcorp subsidiary Sequenom Inc. announces tender offers

and consent solicitations for 5 percent convertible senior notes

due 2017 and 5 percent convertible senior exchange notes due

2018

Read more

BRIEF-Fannie Mae names Ryan Zanin to board of directors

* Fannie Mae names accomplished risk executive Ryan A. Zanin

to the board of directors

Read more

UPDATE 2-Obama enlists Republican Kasich to push for TPP trade deal

WASHINGTON, Sept 16 (Reuters) - Ohio's Republican Governor

John Kasich took over the White House briefing lectern on Friday

to praise the 12-nation Trans-Pacific Partnership, an unusual

move that shows how hard President Barack Obama wants to push

for the trade deal's approval.

Read more

California governor signs epinephrine bill, blasts Mylan

SAN FRANCISCO, Sept 16 (Reuters) - California Governor Jerry

Brown on Friday signed a bill to allow businesses across the

state to carry epinephrine auto-injectors, but sharply

admonished drugmaker Mylan NL over its recent price

increases.

Read more

Novartis says experimental drug helps chronic migraine sufferers

ZURICH, Sept 16 (Reuters) - About 40 percent of chronic

migraine sufferers taking an experimental drug developed by

Novartis and Amgen saw the number of days they

suffered a migraine cut by at least half, beating the placebo in

the trial.

Read more

Protection of Amazon's biodiversity could fuel "fourth industrial revolution" - study

RIO DE JANEIRO, Sept 16 (Thomson Reuters Foundation) - The

Amazon rainforest holds the biological keys to kick-start a

"fourth industrial revolution" if its biodiversity is protected,

said a study published on Friday.

Read more

REFILE- Spiked M&A deals set for record as regulators increase scrutiny

NEW YORK, Sept 16 (IFR) - Bayer will be hoping that its

US$66bn purchase of Monsanto won't succumb to the same failure

that has tripped up many other mergers and acquisitions this

year, as regulators across the globe increase the scrutiny of

deals.

Read more

BRIEF-The Capital Group Compaines increases stake in Capio to 5 pct

* The capital group compaines increases stake in Capio to

7,058,822 shares, corresponding to 5 percent of shares.

Further company coverage:

(Reporting By Johan Ahlander)

Read more

BRIEF-Celgene Corp- releases data on Phase 2 RADIANCE trial

* Celgene Corp -Oral Ozanimod efficacy and safety results at

2 years from Phase 2 RADIANCE trial of patients with relapsing

multiple Sclerosis presented at 32nd Ectrims

Read more

BRIEF-Aphria says board approves fully funded $24.5 mln capital project

* "Board of Directors approved a fully funded $24.5 million

capital project as first phase of its part III expansion"

Source text for Eikon:

Further company coverage:

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BRIEF-Hamilton Thorne announces the acquisition of Embryotech Laboratories

* Hamilton Thorne announces the acquisition of Embryotech

Laboratories

Read more

BRIEF-Navidea says Lymphoseek receives positive opinion in Europe for reduced mass vial

* Navidea's Lymphoseek receives positive opinion in Europe

for a new reduced mass vial

Read more

Astrazeneca says Forxiga combination beats use of drug alone

FRANKFURT, Sept 16 (Reuters) - AstraZeneca said

combining its Forxiga type-2 diabetes drug with older medicine

Bydureon was more effective at controlling blood sugar levels

than treatment with either drug on its own.

Read more

BRIEF-Aphria says board approved a fully funded $24.5 mln capital project as first stage of its Part III expansion

* Aphria Inc says board of directors approved a fully

funded $24.5 million capital project as first phase of its Part

III expansion

Read more

BRIEF-Cesca therapeutics to report fiscal Q4 and FY2016 financial results

* Cesca therapeutics to report fiscal fourth quarter and

full year 2016 financial results and provide business update

Source text for Eikon:

Further company coverage:

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GSK closes UK factory due to flooding

LONDON, Sept 16 (Reuters) - Britain's biggest drugmaker

GlaxoSmithKline said it had been forced to shut a

factory at Maidenhead west of London due to flooding,

potentially causing disruption to the site which produces

toothpaste and mouthwash.

Read more

UPDATE 2-Water protests in tech hub expose urban India's growing pains

* But water, infrastructure challenges loom

(Adds details on Thomson Reuters)

Read more

BRIEF-LifeAssays signs LoI with new distributor in Italy

* Signs letter of intent with new distributor in Italy, EosBio s.r.l.

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Gene Techno Science commences phase III clinical trial for renal anemia treatment drug

* Says it commenced the phase III clinical trial for a renal

anemia treatment drug in Japan

Read more

BRIEF-Pharmstandard unit increases stake in OTCPharm

* Said on Thursday that Pharmstandard unit

Pharmstandard-Leksredstva increased its stake in company to

10.9233 pct from 7.8736 pct

Read more

BRIEF-Ireneusz Plaza sells his entire 16.2 pct stake in Telemedycyna Polska

* Ireneusz Plaza sells 940,000 shares of the company at 0.95

zloty per share lowering his stake in Telemedycyna Polska to 0

percent from 16.2 percent

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Novo Nordisk says semaglutide reduces cardiovascular events by 26 pct

* Says semaglutide-treated diabetes patients had significant

26 pct lower risk of "the primary composite outcome of death"

from cardiovascular causes

Read more

Thursday, September 15, 2016

BRIEF-Stentys H1 operating loss narrows to 4.0 million euros

* Reported on Thursday an H1 operating loss of 4.0 million

euros ($4.49 million) versus a loss of 5.4 million euros a year

ago

Read more

BRIEF-Miraca Holdings names Shigekazu Takeuchi as executive president

* Says it names Shigekazu Takeuchi as executive president,

to succeed Hiromasa Suzuki

Read more

BRIEF-Hainan Haiyao to set up investment unit

* Says it to invest 100 million yuan to set up a wholly

owned investment subsidiary in Hainan

Read more

BRIEF-Hainan Haiyao to set up asset management jv

* Says it to set up an asset management jv in Changsha with

four individuals

Read more

BRIEF-Gilead Sciences prices $5 bln of senior unsecured notes

* Priced $1.25 billion of 2.950% senior notes maturing in

2027

Read more

BRIEF-Walvax Biotechnology unit gets patent license

* Says it received a patent license for extraction of

residual DNA with magnetic beads method

Read more

BRIEF-Guizhou Yibai Pharmaceutical's unit plans medical JV, with partners

* Says its unit plans to invest 5.1 million yuan to set up a

minimally invasive surgical joint venture (medical JV), with

eight individuals

Read more

BRIEF-Guangzhou Boji Medical & Biotechnological gets patent license

Sept 16 (Reuters) - Guangzhou Boji Medical &

Biotechnological Co Ltd :

Read more

BRIEF-Oragenics, Koski Family Limited partnership enters into amendment to June 30, 2016 unsecured promissory note

* Co and Koski Family Limited partnership entered into an

amendment to June 30, 2016 unsecured promissory note - SEC

filing

Read more

BRIEF-Zhejiang Yatai Pharmaceutical raises 1.32 bln yuan via 2015 private placement

Sept 15 (Reuters) - Zhejiang Yatai Pharmaceutical Co.,

Ltd. :

Read more

BRIEF-XOMA provides update from ongoing phase 2 XOMA 358 clinical studies

* XOMA provides update from ongoing phase 2 XOMA 358

clinical studies

Read more

BRIEF-Agilent Technologies prices $300 mln of senior notes

* Notes will mature in September 2026 and will bear interest

at an annual rate of 3.050 percent

Source text for Eikon:

Further company coverage:

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UPDATE 2-Samsung to replace or refund 1 mln U.S. Galaxy Note 7 phones

Sept 15 (Reuters) - Samsung Electronics Co Ltd

formally recalled 1 million Galaxy Note 7 smartphones sold in

the United States, replacing or refunding the flagship phones,

whose susceptibility to catching fire has damaged the image of

the Korean powerhouse.

Read more

Study confirms Zika causes brain birth defects, questions remain

LONDON, Sept 15 (Reuters) - Early results from a crucial

case-control study in Brazil have confirmed a direct causal link

between Zika virus infection in pregnant women and the brain

damaging birth defect microcephaly in their babies, scientists

said on Thursday.

Read more

BRIEF-Lattice closes first tranche of private placement

* Lattice Biologics closes first tranche of private

placement announced on september 13, 2016

Source text for Eikon:

Further company coverage:

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BRIEF-Teleflex approves an increase in size of board from nine to ten directors

* Teleflex Inc says approved an increase in size of board

from nine to ten directors and elected Gretchen R. Haggerty to

board to fill vacancy

Source text - http://bit.ly/2cMMtZt

Further company coverage:

Read more

BRIEF-Amgen presents positive data at EHMTIC 2016, Erenumab reduces migraine

* Amgen presents positive data at EHMTIC 2016 demonstrating

erenumab significantly reduces monthly migraine days in patients

with chronic migraine

Read more

BRIEF-Viveve reports resignation of Brigitte Smith from company board of directors

* Viveve(R) announces resignation of Brigitte Smith from

company board of directors

Source text for Eikon:

Further company coverage:

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BRIEF-Agilent Technologies announces offering of senior notes

* Intends to use proceeds from offering to repay all amounts

outstanding under its revolving credit facility

Source text for Eikon:

Further company coverage:

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BRIEF-Fitch says Bayer, Monsanto deal structure reflects financial risks

* fitch: bayer, monsanto deal structure reflects financial

risks

Read more

UPDATE 2-Teva, Intel to develop wearable tech for Huntington's disease

Sept 15 (Reuters) - Teva Pharmaceutical Industries Ltd

said on Thursday it was collaborating with Intel Corp

to develop a wearable technology platform to track the

progression of disease in patients with Huntington's, a fatal

degenerative disorder.

Read more

Fitch: Bayer, Monsanto Deal Structure Reflects Financial Risks

(The following statement was released by the rating agency)

LONDON, September 15 (Fitch) Bayer's plan to partially finance

the acquisition

of Monsanto with a USD19bn equity and hybrid debt issuance

indicates it has

structured the deal to protect its balance sheet as much as

possible and manage

the financial risks, Fitch Ratings says. The deal is valued at

USD66bn, or

USD4bn more than when we placed Bayer on Rating Watch Negative

in May; however,

this increase is covered by the higher equity

Read more

BRIEF-S&P downgrades Monsanto to 'BBB' on weak operations

* S&P - Monsanto Co. downgraded to 'BBB' on weak operations;

Ratings on creditwatch positive on planned acquisition by Bayer

AG

Read more

BRIEF-Blirt sees negative results in pre-clinical study of its BS-154

* Says pre-clinical study of its BS-154 shows no competitive

advantage and limited commercial implementation possibility for

cancer treatment

Read more

BRIEF-U.S. CPSC - announces recall of GE profile top-loading clothes washers

* Electrical component in washers can overheat, posing a

fire hazard

Read more

Farmers must have choice post Bayer-Monsanto merger - EU's Vestager

PARIS, Sept 15 (Reuters) - European Union anti-trust chief

Margrethe Vestager said on Thursday that farmers must continue

to have a choice when buying seeds and pesticides after the

merger between Bayer and Monsanto.

Read more

RPT-Farmers must have choice post Bayer-Monsanto merger - EU's Vestager

PARIS, Sept 15 (Reuters) - European Union anti-trust chief

Margrethe Vestager said on Thursday that farmers must continue

to have a choice when buying seeds and pesticides after the

merger between Bayer and Monsanto.

Read more

Teva Pharm, Intel to study Huntington disease progression

JERUSALEM, Sept 15 (Reuters) - Teva Pharmaceutical

Industries is collaborating with Intel Corp

to develop a wearable device and machine learning platform for

Huntington disease patients, Teva said on Thursday.

Read more

BRIEF-Mimedx urges FDA to reconsider draft guidances

* Mimedx says continues to believe that its marketing of

its products as section 361 hct/ps is consistent with applicable

statutes and regulations

Read more

UPDATE-1-AcelRx's opioid painkiller succeeds in key study

Sept 15 (Reuters) - AcelRx Pharmaceuticals Inc said

its experimental opioid painkiller was well tolerated in

post-operative patients, including those with organ impairment

and the elderly, in a late-stage study.

Read more

BRIEF-Rigel restructures to focus on Fostamatinib commercialization

* Rigel restructures to focus on fostamatinib

commercialization

Read more

BRIEF-Acelrx reports positive results for ARX-04 in Phase 3 registration trial

* Reports positive results for ARX-04 (sufentanil sublingual

tablet, 30 mcg), including in elderly patients and patients with

organ impairment, in third Phase 3 registration trial, SAP303

Read more

BRIEF-LifeAssays signs distribution agreement for Germany

* Signs distribution agreement with Guder Medizintechnik GmbH

Read more

BRIEF-Episurf Medical obtains its first granted patent in Australia

* Patent covers a surgical drilling guide with a functionality for depth adjustments

Source text for Eikon:

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BRIEF-AnGes MG announces exercise of 22,500 options

* Says 22,500 of 28th warrants were exercised into 2.25

million shares of its common stock from Sep. 14 to Sep. 15,

including 250,000 shares at exercise price 222 yen and 2 million

shares at 214 yen

Read more

BRIEF-Novozymes acquires German research firm Organobalance

* Says will acquire Germany-based research company

Organobalance GmbH for an undisclosed price

Read more

BRIEF-KYORIN Holdings unit enters into co-promotion agreement with MSD K.K

* Says its unit Kyorin Pharmaceutical Company Limited enters

into agreement with MSD K.K, on co-promotion of an allergic

rhinitis treatment, since Nov. 1

Read more

BRIEF-Immunovia: subscription price in rights issue SEK 87/shr

* Says subscription price in rights issue is 87.00 Swedish crowns ($10.23) per share

Read more

BRIEF-Pharnext confirms support for Hereditary Neuropathy Foundation

* Pharnext confirms its continuous support of the Hereditary Neuropathy Foundation to

increase global awareness of Charcot-Marie-Tooth (CMT) disease

Read more

Wednesday, September 14, 2016

Swiss stocks - Factors to watch on Sept 15

ZURICH, Sept 15 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.2 percent lower at 8143 points on Thursday,

according to premarket indications by bank Julius Baer

.

Read more

BRIEF-Nexstim agrees next steps of NBT stroke de novo submission with FDA

* Agrees next steps of NBT stroke de novo submission with FDA

Read more

UPDATE 1-Missouri lawmakers override gun, voter ID vetoes

KANSAS CITY, Mo. (Reuters) - Missouri lawmakers pushed

through bills on Wednesday eliminating the need for permits to

carry concealed weapons and requiring voters to show a photo

identification before casting a ballot, overriding Democratic

Governor Jay Nixon's vetoes of the bills.

Read more

BRIEF-European Commission grants marketing authorisation for Kisplyx in combination with everolimus

* European commission grants marketing authorisation for

kisplyx  (lenvatinib) in combination with everolimus in

advanced renal cell carcinoma

Read more

PRESS DIGEST- British Business - Sept 15

The following are the top stories on the business pages of

British newspapers. Reuters has not verified these stories and

does not vouch for their accuracy.

Read more

UPDATE 6-Bayer clinches Monsanto with improved $66 billion bid

* Bayer says expects deal to close by end-2017

(Adds Breakingviews link)

Read more

BRIEF-Centene expands marketplace offering in Arizona

* Says it estimates that its 2017 Ambetter offerings in

Arizona will provide incremental revenue of over $500 million

Read more

Missouri lawmakers override governor's veto of voter ID bill

KANSAS CITY, Mo., Sept 14 (Reuters) - Missouri lawmakers on

Wednesday overrode Governor Jay Nixon's veto of a bill requiring

voters to show government-issued photo identification in order

to cast a ballot in the state starting in 2017, after this

year's presidential election.

Read more

UPDATE 1-FDA panel recommends dropping serious warning on Pfizer's Chantix

Sept 14 (Reuters) - A serious warning on Pfizer Inc's

quit smoking drug should be removed, 10 of 19

independent panelists to the U.S. Food and Drug Administration

recommended on Wednesday, after reviewing additional trial data

on the controversial treatment.

Read more

BRIEF-Great Basin reports reverse stock split of common stock

* Announced today a 1-for-80 reverse split of its common

stock

Read more

BRIEF-FDA extends PDUFA date for Telotristat Etiprate

* FDA extends PDUFA date for Telotristat Etiprate for the

treatment of Carcinoid Syndrome

Read more

BRIEF-Ventas reports pricing of senior notes offering

* Priced a public offering of $450 million aggregate

principal amount of 3.25% senior notes due 2026 at 99.811% of

principal amount

Read more

BRIEF-Thermo Fisher prices offering of senior notes

* Priced offering of $1.2 billion aggregate principal amount

of its 2.950% senior notes due 2026 at issue price of 98.787% of

principal amount

Read more

BRIEF-John Patience reports 5.1 pct passive stake in Neos Therapeutics

* John Patience reports 5.1 percent passive stake in Neos

Therapeutics Inc as of September 12 - Sec filing

Source text : http://bit.ly/2cOcAhq

Further company coverage:

Read more

FAA proposes $892,500 civil penalty against Air Methods Corp

WASHINGTON, Sept 14 (Reuters) - The U.S. Federal Aviation

Administration has proposed slapping a $892,500 civil penalty on

Air Methods Corp for allegedly operating a helicopter

on passenger-carrying flights when it was not airworthy, the

Transportation Department said on Wednesday.

Read more

BRIEF-GE Digital acquires Meridium Inc

* GE Digital acquires Meridium Inc to accelerate delivery of

comprehensive asset performance management offering for

customers

Read more

CORRECTED-UPDATE 1-Clinton Foundation plans to spin off flagship health project

NEW YORK, Sept 14 (Reuters) - The Bill, Hillary & Chelsea

Clinton Foundation would spin off its flagship health project

into a "completely independent" charity if Hillary Clinton wins

the U.S. presidency in November, the charity announced on

Wednesday.

Read more

Korian raises 2016 core profit margin forecast

Sept 14 (Reuters) - French nursing home operator Korian

raised its core profit margin forecast for 2016 on

Wednesday due to one-off items in the first half and the impact

of IAS 17 accounting standards on its German acquisitions.

Read more

BRIEF-Le Noble Age H1 operating income rises to 17.5 million euros

* H1 net income group share 7.6 million euros ($8.56

million)versus 5.5 million euros year ago

Read more

UPDATE 2-ChemChina seals combination of Israel's Adama with Sanonda

* Sanonda shares have been halted since Aug 2015

(Adds Adama CEO comments)

Read more

UPDATE 2-Aspen Pharmacare moves into China as South Africa sales dip

JOHANNESBURG, Sept 14 (Reuters) - South Africa's Aspen

Pharmacare Holdings will use its recent acquisitions of

GlaxoSmithKline and AstraZeneca product lines to move into

China, the firm's chief executive said.

Read more

Fitch Rates Thermo Fisher's USD Senior Notes Offering 'BBB'; Outlook Stable

(The following statement was released by the rating agency)

NEW YORK, September 14 (Fitch) Fitch Ratings has assigned a

'BBB' rating to

Thermo Fisher Scientific Inc.'s (Thermo Fisher) new USD senior

notes offering.

Fitch expects that the proceeds of the issue will be used to

fund the early call

of the company's $900 million bond due February 2017 and for

general corporate

purposes. The Rating Outlook is Stable.

The ratings apply to approximately $15 billion of debt at June

30, 2016. A full

Read more

BRIEF-IMS Health announces pricing on upsized offering of senior notes in connection with Quintiles IMS merger

* IMS Health announces pricing on upsized offering of senior

notes in connection with Quintiles IMS merger

Read more

BRIEF-Pharmstandard majority shareholder increases its stake to 98.1 pct

* Says Augment Investments Limited under mandatory tender

offer acquired 4.5 million company ordinary shares from

remaining shareholders

Read more

South Africa's Tutu discharged from hospital after surgery

CAPE TOWN, Sept 14 (Reuters) - South African cleric and

anti-apartheid icon Desmond Tutu was discharged from hospital on

Wednesday after a successful surgery to treat recurring

infections that have afflicted him for more than a year, his

family said on Wednesday.

Read more

BRIEF-AEterna Zentaris announces expiration of remaining Series B warrants

* AEterna Zentaris announces expiration of remaining Series

B warrants

Read more

BRIEF-Flexion Therapeutics appoints Mark Stejbach to its board

* Flexion Therapeutics announces appointment of Mark

Stejbach to its board of directors

Read more

BRIEF-Bayer targeting annual cost synergies of $1.2 bln -slides

* Says pays last 12 month ebitda multiple of 18.6x as of may

31, 2016; consensus(3) fy 2017 ebitda multiple of 16.5x

Read more

BRIEF-Biogen Inc affirms strong efficacy of TECFIDERA in both clinical studies and real-world setting

* New Data Affirm Strong Efficacy And well characterized

safety profile of TECFIDERA in both clinical studies and

real-world setting

Read more

Deals of the day-Mergers and acquisitions

Sept 14 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1000 GMT on

Wednesday:

Read more

UPDATE 1-Bayer signs deal worth close to $66 bln to buy Monsanto - source

* Bayer shares up 3 pct

(Adds calculation of overall deal size, comparison to past

deals, future market share)

Read more

Asterias stem cell therapy shows promise in spinal cord paralysis -U.S. study

NEW YORK, Sept 14 (Reuters) - An experimental stem cell

therapy developed by Asterias Biotherapeutics restored

some movement to patients paralyzed by recent spinal cord

injuries, according to interim data from a small study being

presented on Wednesday.

Read more

UPDATE 1-Swiss Alzheimer's biotech AC Immune eyes $700 mln IPO valuation

Sept 14 (Reuters) - AC Immune, the Swiss biotech company

working on treatments for Alzheimer's disease, has set the

pricing band for its keenly awaited U.S. initial public

offering, valuing the firm at about $700 million, at the top end

of the range.

Read more

BRIEF-Biogaia says probiotics to be launched in Kenya, Nigeria and Ghana

* Has signed an exclusive distributor agreement with

Phillips Pharma Group for the rights to sell Biogaia Protectis

drops, tablets and Oral Rehydration Solution in Kenya, Nigeria

and Ghana.

Read more

TABLE-Healthcare & Medical Investment -6 MTH results

Sep 14 (Reuters)

Healthcare & Medical Investment Corporation

FINANCIAL HIGHLIGHTS

(in billions of yen unless specified)

6 months 6 months 6 months 6 months

ended Jul 31, 2016 ended Jan 31, 2016 to Jan 31, 2017 to Jul 31, 2017

LATEST PRIOR COMPANY COMPANY

RESULTS RESULTS FORECAST FORECA

Read more

Tuesday, September 13, 2016

BRIEF-Alliance Pharma says H1 pretax profit up 113 pct

* Weakening of sterling against euro and us dollar that

developed during half year had effect of increasing sales by 2

pct

Read more

NORDIC STOCKS - Factors to watch on Sept 14

The following stocks may be affected by newspaper reports and

other factors on Wednesday:

Read more

BRIEF-GeNeuro Phase 2b Multiple Sclerosis study recruitment reaches halfway mark ahead of schedule

* Phase 2b Multiple Sclerosis study recruitment reaches halfway mark ahead of schedule

Read more

BRIEF-Theradiag H1 revenue up 36 pct at 4.6 million euros

* H1 revenue 4.6 million euros ($5.16 million) versus 3.4

million euros year ago

Read more

BRIEF-Nanobiotix SA files for market approval in Europe for its product NBTXR3

* Has filed for market approval (CE marking) in Europe for

its product NBTXR3

Source text for Eikon:

Further company coverage:

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PRESS DIGEST- Financial Times - Sept 14

Sept 13 (Reuters) - The following are the top stories in the

Financial Times. Reuters has not verified these stories and does

not vouch for their accuracy.

Read more

Swiss biotech AC Immune sets IPO pricing range

Sept 13 (Reuters) - AC Immune SA on Tuesday set the pricing

range for its keenly awaited U.S. initial public offering,

valuing the Swiss biotech firm at about $700 million at the top

end of the range.

Read more

BRIEF-Venaxis reports acquisition of Bioptix

* Acquired as of Sept 12, approximately 98% of voting

shares of Bioptix for about 14% of Venaxis post-deal outstanding

common shares

Source text for Eikon:

Further company coverage:

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BRIEF-Community Healthcare files for mixed shelf of up to $750 million

Source text - http://bit.ly/2cqjcDx

Further company coverage:

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BRIEF-Zynerba reports inducement grant to new chief financial officer

* Zynerba Pharmaceuticals reports inducement grant to new

chief financial officer

Source text for Eikon:

Further company coverage:

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BRIEF-U.S. FDA approves Visumax Femtosecond laser to surgically treat nearsightedness

* FDA approves visumax femtosecond laser to surgically treat

nearsightedness

Read more

BRIEF-Hybrigenics recruits first patient in the clinical study of Inecalcitol

* Recruits the first patient in the clinical study of

Inecalcitol in acute myeloid leukemia

Source text for Eikon: http://bit.ly/2cpnU4p

Further company coverage:

(Gdynia Newsroom:)

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BRIEF-EOS Imaging announces new sale into Carolinas healthcare system

* EOS Imaging announces new sale into Carolinas healthcare

system

Read more

UnitedHealth unit signs deal to take over most Quest billing

NEW YORK, Sept 13 (Reuters) - UnitedHealth Group Inc.

will fold most of Quest Diagnostics Inc's

customer billing into its Optum unit, including taking on 2,400

of the lab company's employees, increasing Optum's business for

such services by 20 percent.

Read more

BRIEF-Aevis Victoria's subsidiary Swiss Medical Network to acquire Generale Beaulieu Holding SA

* Swiss medical network sa - acquisition offer to all the

shareholders of Generale Beaulieu Holding SA - Clinique

Générale-Beaulieu joining Swiss Medical Network

Read more

BRIEF-Abivax completes the second milestone in Carena

* Abivax completes the second milestone in Carena, a

"strategic industrial innovation project" supported by Bpifrance

Source text for Eikon:

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BRIEF-Medtronic receives FDA approval of first drug-coated balloon for treatment of in-stent restenosis

* Medtronic Plc says receives FDA approval of first drug

coated balloon for treatment of in-stent restenosis

Read more

BRIEF-El En H1 net profit jumps at EUR 30.3 mln yoy

* H1 turnover 120.2 million euros ($135.2 million) versus

106.9 million euros year ago

Read more

BRIEF-Vista Partners updates coverage on Cachet Financial Solutions

* Vista Partners updates coverage on Cachet Financial

Solutions, Inc. (OTCQB: CAFN); price target to $21.50

Source text for Eikon:

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BRIEF-Barry Honig submitted letter to CEO of Venaxis conveying concerns regarding co's failed strategic acquisition attempts

* On Sept 13, submitted letter to CEO of Venaxis conveying

concerns regarding co's failed strategic acquisition attempts -

SEC filing

Read more

National Grid Gas takes sterling market by storm in run-up to CBPS

LONDON, Sept 13 (IFR) - National Grid Gas Finance is poised

to sell the biggest ever corporate sterling bond on Tuesday, a

trade that could not have been better timed with the Bank of

England announcing the previous day that four of the issuer's

bonds were eligible for its purchase programme.

Read more

UPDATE 2-Alstom and French government clash over future of Belfort plant

PARIS, Sept 13 (Reuters) - Alstom will go ahead with plans

to shut down manufacturing at its Belfort plant in eastern

France, its CEO told staff on Tuesday, setting up a

confrontation with the French government which vowed "everything

will be done" to prevent that.

Read more

BRIEF-WellDoc announces agreement with LifeScan

* WellDoc announces agreement with LifeScan Inc, a Johnson &

Johnson diabetes care company, to finalize commercial

partnership to deliver combined, best-in-class digital

therapeutic solution for patients with type 2 diabetes

Source text for Eikon:

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BRIEF-Aptinyx receives FDA fast track designation for development of NYX-2925

* Aptinyx receives FDA fast track designation for

development of NYX-2925 as treatment for neuropathic pain

associated with diabetic peripheral neuropathy

Source text for Eikon:

Further company coverage: [Aptinyx inc]

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BRIEF-Regenxbio publishes data from ongoing preclinical studies of NAV gene therapy in Neurodegenerative diseases

* Regenxbio publishes data from ongoing preclinical studies

of NAV gene therapy in neurodegenerative diseases

Read more

BRIEF-Sichuan Languang Development's unit to acquire stake in Tianjin property firm

* Says unit plans to acquire stakes in property firm in

Tianjin city for 1.625 billion yuan ($243.29 million)

Read more

BRIEF-Insulet enrolls first patients in clinical trial for its Omnipod artificial pancreas system

* Enrolls first patients in clinical trial for its Omnipod

artificial pancreas system

Source text for Eikon:

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BRIEF-Jianmin Pharmaceutical Group names chairman, president and CFO

* Says it names Liu Qinqiang as chairman of the board, Xu

Sheng as president and Wang Shaoquan as CFO

Read more

WHO says Angola, Congo yellow fever outbreak under control

GENEVA, Sept 13 (Reuters) - A yellow fever outbreak in

Angola and Congo has been brought under control by a major

vaccination campaign, the head of pandemic and epidemic diseases

at the World Health Organization said on Tuesday.

Read more

Fosun Pharma looks to digest India's Gland, eyes other markets

SHANGHAI, Sept 13 (Reuters) - Chinese drugmaker Shanghai

Fosun Pharmaceutical Group Co Ltd already has one

eye on investments in other overseas markets after it announced

a nearly $1.3 billion deal in July to India's Gland Pharma, the

firm's chairman said on Tuesday.

Read more

BRIEF-Jiangsu Kanion Pharmaceutical to set up pharma JV

* Says it plans to set up pharma JV with registered capital

at 200 million yuan ($29.94 million)

Read more

UPDATE 1-U.S. hedge fund Elliot Management ups Arcam stake, share rises

* U.S. hedge fund Elliot Management has raised its stake in

Swedish 3D printer maker Arcam to 6.6 percent of

shares and votes, through its investment vehicle Elliot Capital

Advisors, L.P., a filing from the Swedish FSA showed on Tuesday

Read more

BRIEF-Alliance Pharma says signed agreement for Diclectin in Europe

* Has signed a further licensing and distribution agreement

with Duchesnay Inc. Of Canada

Read more

BRIEF-Mauna Kea Technologies Cellvizio placed at hospital in New York

* Announced on Monday the placement of a Cellvizio System,

the multidisciplinary confocal laser endomicroscopy platform,

at The Mount Sinai Hospital in New York, NY

Read more

Monday, September 12, 2016

Swiss stocks - Factors to watch on Sept 13

ZURICH, Sept 13 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.5 percent higher at 8,243 points on Tuesday,

according to premarket indications by bank Julius Baer

.

Read more

BRIEF-Anges MG announces exercise of options

* Says 8,700 of 28th warrants were exercised into 870,000

shares of its common shares from Sep. 7 to Sep. 13, comprised of

170,000 shares at exercise price 233 yen, 270,000 shares at 230

yen, 100,000 shares at 234 yen, 180,000 shares at 229 yen and

150,000 at 219 yen

Read more

BRIEF-Basilea: supply, distribution and license agreement with GBT

* Basilea announces supply, distribution and license agreement with Grupo Biotoscana for

CRESEMBA (isavuconazole) and Zevtera (ceftobiprole) in Latin America

Read more

Cancer overtakes heart disease as Australia's biggest killer

SYDNEY, Sept 13 (Reuters) - Cancer has become Australia's

biggest killer, overtaking heart disease for the first time to

take more lives than any other ailment, a government health

agency said in a report released on Tuesday.

Read more

UPDATE 2-Obama asks U.S. insurers for help enrolling the young and healthy

Sept 12 (Reuters) - President Barack Obama on Monday urged

U.S. insurers offering coverage next year under his national

healthcare law to step up their efforts to enroll those who

remain uninsured, especially younger and healthier Americans.

Read more

UPDATE 1-Obama hopeful on spending, Zika funds after meeting Congress leaders

WASHINGTON, Sept 12 (Reuters) - President Barack Obama said

after meeting with the top four congressional leaders on Monday

he was encouraged that lawmakers would be able to pass short

term spending legislation to keep the government open during the

2017 fiscal year.

Read more

Obama asks U.S. insurers for help enrolling the young and healthy

Sept 12 (Reuters) - President Barack Obama on Monday urged

U.S. insurers offering coverage next year under his national

healthcare law to step up their efforts to enroll those who

remain uninsured, especially younger and healthier Americans.

Read more

BRIEF-Catherine Johanna Defrancesco reports 7.49 pct stake in Venaxis as of Sept. 2

* Catherine Johanna Defrancesco reports 7.49 percent stake

in Venaxis Inc as of Sept. 2 - Sec filing

Source text (http://bit.ly/2czSv2y)

Further company coverage:

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Obama says hopeful on spending, Zika after meeting Congress leaders

WASHINGTON, Sept 12 (Reuters) - President Barack Obama said

after meeting with congressional leaders on Monday he was

encouraged that Congress would be able to pass short term

spending legislation to keep the government open.

Read more

Engine failure led to foot-long hole in Southwest airliner -agency

Sept 12 (Reuters) - An engine failure on a Southwest

Airlines Co jet on Aug. 27 released debris that tore a 5

inch by 16 inch (13 cm by 41 cm) hole in the plane before it

made a safe emergency landing in Pensacola, Florida, U.S. crash

investigators said on Monday.

Read more

BRIEF-Bow Street LLC reports 5.3 pct passive stake in Adamas Pharmaceuticals as of Sept 2

* Bow Street Llc reports 5.3 percent passive stake in Adamas

Pharmaceuticals Inc as of September 2 -Sec filing

Source text (http://bit.ly/2cI06YG)

Further company coverage:

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RPT-UPDATE 3-FDA staff flags concerns about Pfizer's quit-smoking drug study

Sept 12 (Reuters) - Pfizer Inc's trial data on

Chantix, a drug to help people quit smoking, failed to impress

U.S. Food and Drug Administration scientists, in a blow to the

company's attempts to have a serious warning removed from the

drug's label.

Read more

UPDATE 1-UK will have public guidelines for Brexit talks before triggering Article 50 - minister

LONDON, Sept 12 (Reuters) - Britain will make public its

guidelines for talks on leaving the European Union by the time

it triggers the exit process, Brexit minister David Davis said

on Monday, in the first indication of when Britons will find out

what the government hopes to achieve in the talks.

Read more

BRIEF-Genoway H1 net income up at 180,000 euros

* H1 net income 180,000 euros ($202,122) versus 22,000 euros year ago

Read more

BRIEF-Supersonic Imagine H1 operating loss narrows to 6.2 million euros

* Supersonic imagine announces its results for the first

half of 2016

Read more

UPDATE 2-FDA staff flags concerns about Pfizer's quit-smoking drug study

Sept 12 (Reuters) - Pfizer Inc's trial data on

Chantix, a drug to help people quit smoking, failed to impress

U.S. Food and Drug Administration scientists, in a blow to the

company's attempts to have a serious warning removed from the

drug's label.

Read more

RPT-UPDATE 2-Horizon Pharma to buy Raptor Pharma for $800 mln

Sept 12 (Reuters) - Horizon Pharma Plc said it

would buy Raptor Pharmaceutical Corp for nearly $800

million to bolster its portfolio of drugs to treat rare diseases

and reduce its dependence on the primary care market.

Read more

UPDATE 2-Horizon Pharma to buy Raptor Pharma for $800 mln

Sept 12 (Reuters) - Horizon Pharma Plc said it

would buy Raptor Pharmaceutical Corp for nearly $800

million to bolster its portfolio of drugs to treat rare diseases

and reduce its dependence on the primary care market.

Read more

UPDATE 2-Trump says health is an 'issue' after Clinton pneumonia revelation

WASHINGTON, Sept 12 (Reuters) - Republican presidential

candidate Donald Trump said on Monday that health is an issue in

the election campaign after his Democratic rival, Hillary

Clinton, revealed she had pneumonia, and he said he would soon

release detailed information about his health.

Read more

BRIEF-Regeneron says Bonnie Bassler, Huda Zoghbi elected to board

* Regeneron announces election of Bonnie Bassler, ph.d., and

Huda Zoghbi, m.d., to board of directors

Source text for Eikon:

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BRIEF-FDA staff say neuropsychiatric risk with Pfizer's quit-smoking drug varies in studies, trial design has limitations

* Neuropsychiatric risk with Pfizer's quit-smoking drug

varies in studies, trial design has limitations & biases that

affect interpretation

Read more

BRIEF-Perrigo acknowledges receipt of letter from Starboard Value

* Perrigo acknowledges receipt of letter from Starboard

Value LP

Read more

BRIEF-Xencor doses first patient in blood cancer test

* Oncology bispecific program XmAb14045 for the treatment of

acute myeloid leukemia and other CD123-expressing hematologic

malignancies

Read more

BRIEF-Karyopharm appoints Humphrey A.R.Gardner as senior VP, clinical development

* Karyopharm appoints Humphrey A.R. Gardner MD, FCAP, as

senior vice president, clinical development

Source text for Eikon:

Further company coverage:

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BRIEF-Horizon Pharma Plc to acquire Raptor Pharmaceutical corp

* Horizon Pharma Plc to acquire Raptor Pharmaceutical Corp.

as further step in building leading rare disease business

Read more

BRIEF-Contravir Pharmaceuticals reports new CRV431 data

* Reports new CRV431 data highlighting synergistic activity

with CMX157 against hepatitis B

Read more

BRIEF-Intercept said on Sept 8, court granted final approval of previously announced agreement with lead plaintiff

* On Sept 8, court granted final approval of previously

announced agreement with lead plaintiff to settle purported

securities class action litigation

Read more

BRIEF-Tong Hua Shuang Long's pharma unit to invest 347 mln yuan in anti-HIV medicine project

Sept 12 (Reuters) - Tong Hua Shuang Long Chemical Industry

Co Ltd

Read more

BRIEF-Nexstim concludes co-operation negotiations

* Maximum of 2 people will be permanently laid off and one person will be working part time

in future

Read more

Investors stay positive as corporate yields turn negative

LONDON, Sept 12 (IFR) - Investors, doing their best to

remain positive even as corporate bonds descend deeper into

negative yielding territory, bought two new issues with negative

yields last week as the strength of central bank action

continued to promote perverse incentives.

Read more

GSK sells anaesthetics to Aspen for up to $370 mln

LONDON, Sept 12 (Reuters) - GlaxoSmithKline is to

sell its portfolio of anaesthetic drugs to South Africa's Aspen

Pharmacare for up to 280 million pounds ($372 million)

as part of a drive by the British drugmaker to focus on core

therapy areas.

Read more

BRIEF-Aspen Pharma to buy almost entire of GSK's anaesthetics portfolio

* Signed an agreement with GSK whereby AGI will acquire a

portfolio of anaesthetics globally with exception of certain

territories

Read more

Thai authorities downplay Zika risk, worried by tourism impact

BANGKOK, Sept 12 (Reuters) - Health and city officials in

Thailand downplayed risks from rising infections from the

mosquito-borne Zika virus, which is linked to serious birth

defects, and expressed concern that disclosing information would

damage its tourism industry.

Read more

Sunday, September 11, 2016

BRIEF-Pixium Vision gets clinical trial approval from Spanish Ministry of Health

* Pixium Vision receives clinical trial approval from Spanish Ministry of Health for 150

electrode IRIS II bionic vision system

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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Swiss biotech firm ADIENNE says plans IPO

ZURICH, Sept 12 (Reuters) - Swiss biotechnology firm ADIENNE

said on Monday it plans to seek a listing on Switzerland's

bourse in an initial public offering.

Read more

BRIEF-Onxeo announces first outcomes of Livatag preclinical plan

* Livatag nanoformulation leads to increased exposure and preferential affinity for liver,

supporting current relive phase III study rationale

Read more

BRIEF-LG Chem to merge with LG Life Sciences Ltd

* Says merger rate of 1 : 0.2606772 for common shares and 1

: 0.2534945 for preferred shares between the company and LG Life

Sciences

Read more

UPDATE 1-LG Chem to buy LG Life Sciences for nearly $1 bln

SEOUL, Sept 12 (Reuters) - South Korean chemicals and

battery maker LG Chem on Monday said it plans to

acquire pharmaceutical affiliate LG Life Sciences

for about 1.1 trillion won ($989.56 million) to make its bio

business a new growth engine.

Read more

LG Chem says to buy LG Life Sciences to boost bio business

SEOUL, Sept 12 (Reuters) - South Korean chemicals and

battery maker LG Chem on Monday said it plans to

acquire pharmaceutical affiliate LG Life Sciences to

expand its bio business.

(Reporting by Hyunjoo Jin; Editing by Stephen Coates)

Read more

BRIEF-BeiGene receives approval to initiate clinical trials in China with PD-1 antibody BGB-A317

* Beigene Receives Approval To Initiate Clinical Trials In

China With Pd-1 antibody bgb-a317

Read more

UPDATE 1-Merkel aide optimistic conservatives will overcome migrant cap dispute

BERLIN, Sept 11 (Reuters) - Chancellor Angela Merkel's Chief

of Staff said on Sunday he was confident Germany's sister

conservative parties, whose unity is threatened by a row over

migrant policy just a year before a federal election, would soon

sort out their differences.

Read more

UPDATE 1-Israel Chemicals, hurt by weak potash prices, names interim CEO

* COO Asher Brinbaum named as interim CEO

(Recasts with appointment of interim CEO)

Read more

U.S. Justice Department subpoenas Taro over generic drug pricing

WASHINGTON, Sept 11 (Reuters) - Taro Pharmaceutical

Industries Ltd. and two of its senior officers received

grand jury subpoenas last week in connection with a federal

antitrust investigation into generic drug pricing, the company

disclosed late on Friday.

Read more

Eight pregnant women among 329 infected by Zika in Singapore-govt

SINGAPORE, Sept 11 (Reuters) - Eight pregnant women have

been infected by the Zika virus among the 329 cases in

Singapore, the government said on Sunday.

Read more

Israel Chemicals faces tough road to recovery after CEO steps down

JERUSALEM, Sept 11 (Reuters) - Stefan Borgas stepping down

as chief executive is the latest in a series of issues that have

plagued Israel Chemicals (ICL), and the company's

fortunes are not expected to turn around in the foreseeable

future given very low potash prices.

Read more

Hollande to meet ministers over Alstom's plans for Belfort plant

PARIS, Sept 11 (Reuters) - French President Francois

Hollande will meet Prime Minister Manuel Valls and ministers in

charge of economic and transport policy on Monday morning to

discuss trainmaker Alstom's sudden decision to scale down its

Belfort plant, the president's office said.

Read more

Thailand finds 21 new cases of Zika in Bangkok, including pregnant woman

BANGKOK, Sept 11 (Reuters) - Twenty-one new cases of

locally-transmitted Zika virus have been confirmed in central

Bangkok, including a pregnant woman who later gave birth with no

complications, Thailand's public health ministry said on Sunday.

Read more

Saturday, September 10, 2016

BRIEF-Cytokinetics announces additional results from COSMIC-HF

* Announces additional results from COSMIC-HF to be

presented at the HFSA Annual Scientific Meeting

Source text for Eikon:

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Friday, September 9, 2016

BRIEF-Unitedhealth says Director Richard Burke reports open market sale of 20,000 shares of co

* Director Richard Burke reports open market sale of 20,000

shares of co's common stock at average price of $135.8 per share

on SEPT 7 - SEC filing

Source: (http://bit.ly/2c6wYif)

Further company coverage:

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Executives see little progress on easing Cuba-U.S. financial services

NEW YORK, Sept 9 (Reuters) - Multinational financial

companies met on Friday with U.S. and Cuban officials to discuss

making financial transactions between the two countries easier

but reported no concrete signs of progress.

Read more

BRIEF-Biodel enters into an asset purchase and license agreement with Unilife Corp and Unilife Medical Solutions

* On September 2, 2016, co, Unilife Corp and Unilife Medical

Solutions Inc entered into an asset purchase and license

agreement

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BRIEF-Promis Neurosciences announces completion of private placement offering

* Announces completion of private placement offering

Source text for Eikon:

Further company coverage:

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BRIEF-GE sets quarterly dividend of $0.23 per share

* Sets quarterly dividend of $0.23 per share

Source text for Eikon:

Further company coverage:

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UPDATE 2-Teva says aims to launch EpiPen-like device by 2018 in U.S.

Sept 9 (Reuters) - Teva Pharmaceutical Industries Ltd

said Friday it aims to win U.S. approval by late 2017

or early 2018 for its version of Mylan NV's EpiPen

device for treating severe allergic reactions, a move that would

challenge the branded product's overwhelming market dominance.

Read more

BRIEF-Abbvie sets quarterly cash dividend of $0.57per share

* Sets quarterly cash dividend of $0.57per share

Source text for Eikon:

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BRIEF-Apobiologix comments on patent infringement litigation about Grastofil, Lapelga

* Positive Court Decision In Patent Infringement Litigation

Against Amgen Concerning Grastofil And Lapelga Products

Read more

Teva says hoping to launch EpiPen-like device by 2018 in U.S.

Sept 9 (Reuters) - Teva Pharmaceutical Industries Ltd

on Friday said it hopes to win U.S. approval by late

2017 or early 2018 for its version of Mylan NV's EpiPen

device to treat severe allergic reactions, a move that could

challenge the branded product's overwhelming dominance.

Read more

Clinton spokeswoman defends drug plan after Pfizer comments

NEW YORK, Sept 9 (Reuters) - U.S. Presidential candidate

Hillary Clinton's spokeswoman said on Friday Clinton's plan to

curb drug spending was not the blow to medical innovation that

Pfizer Inc Chief Executive Ian Read described it as

being on Thursday.

Read more

BRIEF-Draegerwerk to buy back shares for employee stock program

* Announces share buyback for the employee participation

program

Read more

BRIEF-Colucid Pharmaceuticals announces pricing of public offering

* Colucid Pharmaceuticals announces pricing of public

offering of common stock

Read more

BRIEF-Oncology Venture incorporates 2X Oncology Inc., a Women's Cancer Company in the US

* Says has incorporated an oncology therapeutics spin-out, 2X Oncology Inc., in the US

Read more

BRIEF-Novo Nordisk issues nationwide recall of six batches of glucagen hypokit

* Novo Nordisk Inc issues voluntary nationwide recall of six

batches of glucagen hypokit due to detached needles on syringe

in kit

Read more

BRIEF-PExA AB sells PExA 2.0 to Karolinska Institutet

* Karolinska Institutet's Unit acquires a complete system, PExA 2.0

Read more

BRIEF-ViewRay wins China FDA approval for its MRIdian system

* Says has received china food and drug administration

approval for its mridian system

Source text for Eikon:

Further company coverage:

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BRIEF-Proteostasis Therapeutics prices common stock offering

* Proteostasis therapeutics announces pricing of public

offering of common stock

Read more

BRIEF-Crescita says topical anesthetic Pliaglis wins Mexico approval

* Crescita therapeutics announces approval of Pliaglis in

mexico

Read more

EU regulators halt Dow, DuPont merger review to gather data

BRUSSELS, Sept 9 (REUTERS) - EU antitrust regulators have

halted their scrutiny of Dow Chemical Co and DuPont's

proposed merger while the companies provide more

information regarding their $130 billion deal.

Read more

BRIEF-Medivir reports positive phase IIa data for simeprevir

* Interim results from phase IIa trial evaluating triple

combination including simeprevir demonstrates high level of

efficacy in HCV patients

Read more

UPDATE 1-Ivory Coast re-opens western borders closed during Ebola epidemic

ABIDJAN, Sept 9 (Reuters) - Ivory Coast has re-opened its

western borders with Liberia and Guinea two years after they

were closed to prevent the spread of an Ebola epidemic that

killed thousands across West Africa, an Ivorian government

spokesman said on Friday.

Read more

Ivory Coast re-opens western borders closed during Ebola epidemic

ABIDJAN, Sept 9 (Reuters) - Ivory Coast has re-opened its

western borders with Liberia and Guinea two years after they

were closed to prevent the spread of an Ebola epidemic that

killed thousands across West Africa, an Ivorian government

spokesman said on Friday.

Read more

UPDATE 1-Duterte says he told Obama he never insulted him, thinks UN's Ban a fool

JAKARTA, Sept 9 (Reuters) - Philippine President Rodrigo

Duterte told Barack Obama he never called him a "son of a

bitch", he said on Friday, but he maintained a defiant stance on

his war on drugs, saying U.N. chief Ban Ki-moon was a fool for

bringing up human rights.

Read more

BRIEF-Cellumed to issue 3 bln won worth convertible bonds

* Says it will issue the 16th unregistered/unsecured private

convertible bonds, raising 3 billion won in proceeds for

operations

Read more

BRIEF-Hafslund: August network energy delivery down at 1067 GWh

* August 2016 network energy delivery 1067 GWh versus 1071 GWh year ago

Read more

BRIEF-Sage Therapeutics announces public offering of 4.40 mln common shares priced at $39.75/share

* Says public offering of 4.40 million common shares priced

at $39.75per share

Source text for Eikon:

Further company coverage:

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BRIEF-Evolent Health announces pricing of upsized secondary public offering of class A common stock

* Announces pricing of upsized secondary public offering of

class a common stock

Read more

Duterte says he told Obama he never insulted him, thinks UN's Ban a fool

JAKARTA, Sept 9 (Reuters) - Philippine President Rodrigo

Duterte told Barack Obama he never called him a "son of a

bitch", he said on Friday, but he maintained a defiant stance on

his war on drugs, saying U.N. chief Ban Ki-moon was a fool for

bringing up human rights.

Read more

BRIEF-Caregen to invest 32.8 bln won to establish new unit in US

* Says it will invest 32.8 billion won to establish new

wholly owned unit in the United States, namely Caregen Biopharma

Inc.

Read more

Thursday, September 8, 2016

BRIEF-Pihlajalinna signs deal with Tervola municipality

* Says Tervola has chosen Pihlajalinna as municipality's social and healthcare services

partner

Read more

BRIEF-Dechra Pharmaceuticals gets FDA approval for first U.S. generic entrant antibiotic

* Dechra is pleased to announce that it has received

approval from the U.S. Food and Drug Administration (FDA) for a

generic antibiotic

Read more

German stocks - Factors to watch on September 9

FRANKFURT/BERLIN, Sept 9 (Reuters) - The following are some

of the factors that may move German stocks on Friday:

Read more

BRIEF-Novartis says Niji system may provide earlier diagnosis of severe allergic asthma

* Says new Novartis point of care Niji system may provide

earlier diagnosis of severe allergic asthma and faster treatment

decisions

Source text for Eikon: [http://pdf.reuters.com/htmlnews/htmlnews.asp?i=43059c3bf0e37541&u=urn:newsml:reuters.com:20160909:nGNERJK5S

]

Further company coverage:

(Reporting by Zurich Newsroom)

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BRIEF-Celltrion receives patent

* Says it receives patent on Sept. 9, for human monoclonal

antibody generated from human B-cells able to neutralize

influenza A viruses

Read more

Mistrust of vaccines is greatest in France - survey

LONDON, Sept 9 (Reuters) - Public confidence in immunisation

varies widely across the world with the French the most

sceptical about the safety of vaccines, according to a survey

published on Friday.

Read more

Statins' benefits understated and harms exaggerated, scientists warn

LONDON, Sept 8 (Reuters) - The benefits of statins -

cholesterol-busting drugs that can dramatically reduce the risk

of heart attacks and strokes - have been underestimated and

their harms exaggerated, scientists said on Thursday in a major

review of research.

Read more

BRIEF-IsoRay q4 loss per share $0.02

* Quarterly loss per share $0.02

Source: (http://bit.ly/2cxhHTh)

Further company coverage:

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BRIEF-Broadwood Partners reports 13.8 pct stake in Oncocyte Corp

* Reports 13.8 percent stake in Oncocyte Corp, as of August

29, 2016 - SEC filing

Source: (http://bit.ly/2cdBnNj)

Further company coverage:

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CORRECTED-BRIEF-iCAD says co's CFO and COO Kevin Burns to resign

* Kevin Burns, president, chief financial officer and chief

operating officer, is resigning from company effective September

23, 2016

Read more

U.S. taxable bond funds net $3.4 bln in latest week - Lipper

NEW YORK, Sept 8 (Reuters) - Investors added $3.4 billion in

cash to U.S.-based taxable bond funds during the week through

Sept. 7, Thomson Reuters Lipper data showed on Thursday, marking

the funds' fourth week in five of posting positive flows.

Read more

BRIEF-Streamline Health acquires Opportune IT Healthcare Solutions

* Streamline health acquires opportune it healthcare

solutions

Read more

BRIEF-Lantheus Holdings announces public offering of 5,200,000 shares of common stock

* Lantheus holdings, inc. Announces public offering of

5,200,000 shares of common stock

Read more

"Trojan Horse" antibody plan shows promise against Ebola viruses

LONDON, Sept 8 (Reuters) - Scientists have found a hidden

weak spot shared by all five known types of the deadly Ebola

virus and successfully targeted it with two antibodies which

blocked its ability to invade human cells.

Read more

UPDATE 1-Biden asks U.S. Congress to allow unencumbered Zika funding vote

WASHINGTON, Sept 8 (Reuters) - Vice President Joe Biden on

Thursday called on the Republican-led U.S. Congress to allow an

up-or-down vote on funding to combat the Zika virus without

other provisions attached, calling the health threat posed by

the pathogen a national emergency.

Read more

BRIEF-Bayer to explore sale of $1.1 bln dermatology business - Bloomberg

* Bayer said to explore sale of $1.1 billion dermatology

business - Bloomberg, citing source

Read more

BRIEF-Euronext announces quarterly revision of Belgian indices

* Announces quarterly review of the BEL 20, BEL Mid

and BEL small indices

Read more

BRIEF-Boiron H1 net income group share rises 23.3 pct

* Reports H1 net income group share of 26.5 million euros

versus 21.5 million euros a year ago

See also:

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Boiron H1 operating profit up 14.7 mln at 43.4 mln euros

* H1 sales is 284.3 million euros ($320.1 million) versus

275.6 million euros a year ago

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German online pharmacy Shop-Apotheke plans Frankfurt listing - sources

FRANKFURT, Sept 8 (Reuters) - Online pharmacy Shop Apotheke

is planning a Frankfurt stock market listing as it seeks to

generate cash for its expansion, taking advantage of buoyant

equity markets, people familiar with the matter said.

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UPDATE 1-French govt summons Alstom boss over end to trainmaking in Belfort

PARIS, Sept 8 (Reuters) - The head of Alstom was

summoned by the French government for an explanation on Thursday

after the company revealed plans to bring over 130 years of

trainmaking to an end at its Belfort plant in eastern France.

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UPDATE 1-EU court says Lundbeck pay-for-delay deals anti-competitive

LUXEMBOURG, Sept 8 (Reuters) - Danish drugmaker Lundbeck's

deals with smaller rivals to delay cheaper generic

copies of its blockbuster citalopram anti-depressant from

entering the market were anti-competitive, a European Union

court said on Thursday.

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BRIEF-Clovis Oncology -FDA has notified it is not currently planning to hold advisory committee meeting to discuss for Rucaparib

* FDA has notified co that FDA is not currently planning to

hold advisory committee meeting to discuss NDA for Rucaparib

Source text: [http://bit.ly/2c9EYtK]

Further company coverage:

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BRIEF-Chrono Therapeutics raises $47.6 million in series B financing

* Chrono Therapeutics raises $47.6 million in series B

financing to advance its clinical platform for personalized drug

therapy

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BRIEF-Tokai Pharmaceuticals announces review of strategic alternatives

* Tokai Pharmaceuticals announces review of strategic

alternatives

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BRIEF-PZ Cormay to issue series L shares to shareholders of Orphee

* To issue up to 16,695,541 series L shares to shareholders

of Orphee SA in exchange for Orphee's shares

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Octiv says secured a investment from GE Ventures

* Octiv says investment was part of a round totaling $4.75

million

Source text for Eikon:

Further company coverage:

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BRIEF-Barry Honig reports 9.6 pct stake in Venaxis

* Barry Honig Reports 9.6 Pct Stake In Venaxis Inc as of

September 6, 2016 - SEC filing

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BRIEF-Health&Life says change of general manager

* Says its general manager resigned on Sep. 2 and it

appoints Paul Yang as acting general manager

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