Saturday, April 30, 2016

BRIEF-Dole Foods says it has recently been contacted by the U.S. DOJ

* "concerned about recent stories in some publications about

the FDA's observation report"

Read more

Buffett, Munger slam Valeant; drugmaker turned into 'a sewer'

NEW YORK, April 30 (Reuters) - Warren Buffett and Charlie

Munger made clear that they are no fans of embattled drugmaker

Valeant Pharmaceuticals International Inc .

Read more

Friday, April 29, 2016

BRIEF-Anthera Pharma amends purchase agreement with Lincoln Park Capital

* On april 27, 2016, Co, Lincoln Park Capital Fund, LLC

entered amendment to purchase agreement, dated as of march 12,

2015

Read more

BRIEF-Moody's says Alere's receipt of lender approval for amendment is a positive development

* Alere's receipt of lender approval for amendment and

waiver is a positive development; ratings unaffected

Source text (http://bit.ly/1VYiBej)

(Bengaluru Newsroom; +1 646 223 8780; )

Read more

BRIEF-Harvard Bioscience Q4 non-GAAP earnings per share $0.03

* Reports Fourth Quarter And Year-End 2015 results,

preliminary first quarter 2016 revenues and 2016 financial

guidance

Read more

BRIEF-Agile Therapeutics says Caxton Corp reports 5.4 pct passive stake in company

* Caxton Corporation reports 5.4 percent passive stake in

Agile Therapeutics Inc as of April 27, 2016 - SEC filing

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Amicus Therapeutics files for potential mixed shelf

* Files for potential mixed shelf; size not disclosed - sec

filing

Source text [http://1.usa.gov/1roaqvt]

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Manitex says affiliate, Ortho Regenerative, has filed final prospectus

* Manitex Capital Inc announces that its affiliate, Ortho

Regenerative Technologies Inc, has filed a final prospectus

Source text for Eikon:

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BRIEF-Visiomed FY net loss group share widens to 7.3 million euros

* FY net loss group share of EUR 7.3 million ($8.35

million) versus loss of EUR 2.6 million year ago

Read more

BRIEF-Neuron Bio FY net result turns to profit of 88,499 euros

* FY net profit 88,499 euros ($101,216) versus loss 2.6 million euros year ago

Read more

BRIEF-Diagnostic Medical Systems FY net loss group share widens to 1.5 million euros

* FY net loss group share of 1.5 million euros versus loss

of 1.1 million euros year ago

Read more

BRIEF-Catalent says new order lifts suspension of pharmaceutical operations

* Softgel manufacturing facility received order from

L'agence National De Sécurité Du Médicament Et Des Produits De

Santé

Read more

BRIEF-Valeant says Michael Pearson 2015 total compensation $143.1 mln

April 29 (Reuters) - Valeant Pharmaceuticals International

Inc

Read more

BRIEF-Biocept announces pricing of $5 mln public offering

* Biocept, inc. Announces pricing of $5 million public

offering of common stock and warrants

Read more

BRIEF-Quebec regulator receives Valeant request to lift cease-trade order

April 29 (Reuters) - Valeant Pharmaceuticals International

Inc has requested that Quebec securities regulator

Autorite des Marches Financiers lift its cease-trade order

against directors and key officers

Read more

BRIEF-Janssen's Imbruvica receives CHMP opinion for use in lymphocytic leukaemia patients

* Janssen's Imbruvica (ibrutinib) receives positive CHMP

opinion for expanded use in previously untreated chronic

lymphocytic leukaemia patients

Read more

BRIEF-Valeant says 3 new independent directors nominated to board

April 29 (Reuters) - Valeant Pharmaceuticals International

Inc :

Read more

Sanofi says committed to Medivation takeover

PARIS, April 29 (Reuters) - Sanofi said on Friday

it remained committed to acquiring U.S. drug firm Medivation

and that it was ready to speak directly to its

shareholders.

Read more

BRIEF-Medivation board rejects Sanofi's takeover offer

* Medivation's board of directors unanimously rejects

Sanofi's unsolicited proposal

Read more

BRIEF-Alere announces commencement of consent solicitations for its notes

* Alere Inc. announces commencement of consent solicitations

for Alere Inc.'s notes

Read more

BRIEF-Neumodx Molecular raises about $20 mln in equity financing

* Files To Say It Raised About $20 Mln In Equity Financing -

Sec filing

Source text: (http://1.usa.gov/1r1JPDY)

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Hill-Rom qtrly earnings per diluted share of $0.33

* Rom reports higher year-over-year revenue and adjusted

earnings and updates full year outlook

Read more

BRIEF-Shinva Medical Instrument's shares to resume trade

Further company coverage:

(Reporting by Hong Kong newsroom)

Read more

BRIEF-Eifelhoehen Klinik FY net loss 0.97 million euros

* FY group revenue 45.98 million euros ($52.32 million) versus 42.81 million euros year ago

Read more

BRIEF-Shinva Medical Instrument to raise up to 2.2 bln yuan in private placement

* Says it plans to raise up to 2.2 billion yuan ($339.39

million) in private placement of shares to fund projects,

replenish capital

Read more

German stocks - Factors to watch on April 29

FRANKFURT, April 29 - The DAX top-30 index looked

set to open 0.8 percent lower on Friday, according to premarket

data from brokerage Lang & Schwarz at 0619 GMT.

Read more

BRIEF-Theravance Biopharma prices public offering of 4.8 mln shares at $21/share

* Theravance Biopharma announces pricing of public offering

of its ordinary shares

Read more

Thursday, April 28, 2016

BRIEF-Ampliphi Biosciences files for stock shelf of up to $75 mln

* Files for stock shelf of up to $75 million - sec filing

Source text: http://1.usa.gov/1SwOqZu

Further company coverage:

Read more

BRIEF-Medivation CEO total 2015 compensation $9.6 million

* Ceo david hung's total 2015 compensation $9.6 million

versus $10.6 million in 2014

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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U.S. military punishes 16 over 2015 Afghan hospital bombing

WASHINGTON, April 28 (Reuters) - The U.S. military will

announce on Friday that has it taken disciplinary action against

16 service members over a deadly Oct. 3 air strike in

Afghanistan that destroyed a hospital run by the international

medical charity Medecins Sans Frontieres, U.S. officials tell

Reuters.

Read more

UPDATE 3-AbbVie forges deeper into cancer, as clock ticks for Humira

April 28 (Reuters) - AbbVie Inc placed another big

bet on new cancer drugs on Thursday with a $5.8 billion

acquisition that could lessen its dependence on arthritis

treatment Humira, the world's top selling drug.

Read more

UPDATE 3-Bristol raises 2016 forecast after earnings beat

April 28 (Reuters) - Bristol-Myers Squibb Co

ratcheted up its 2016 profit view after trouncing first-quarter

sales and earnings forecasts on strong demand for its new Opdivo

immuno-oncology drug and Eliquis blood clot preventer.

Read more

US condemns Syria hospital attack, urges Russia to use influence with Damascus

WASHINGTON, April 28 (Reuters) - The U.S. State Department

said on Thursday that Syria's air strike on a hospital in Aleppo

was "reprehensible," and it called on Russia to use its

influence to pressure Syrian President Bashar al-Assad's

government to stop the attacks.

Read more

BRIEF-Pharma Mar Q1 net result swings to loss of 7.1 mln euros

* Q1 net loss 7.1 million euros ($8.0 million) versus profit

6.5 million euros year ago

Read more

BRIEF-1Nkemia FY net profit down at 265,629 euros

* FY net profit 265,629 euros ($300,851) versus 628,455 euros year ago

Read more

BRIEF-Immunotec nominates Mario Paradis to its board of directors

* Immunotec announces the nomination of Mario Paradis to its

board of directors and reports AGM results

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

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BRIEF-Aduro Biotech announces key preclinical data published

* Aduro Biotech announces key preclinical data published

highlighting new approach to treat multiple myeloma

Read more

BRIEF-Agenus reports Q1 loss per share $0.37

* Agenus reports first quarter 2016 financial results and

operational progress

Read more

BRIEF-Celgene says 2020 Revlimid forecast is conservative: conf call

April 28 (Reuters) - Celgene Execs Say Otezla Continues To

Grow At Similar Rate After Novartis' Cosentyx Launch - Conf Call

Read more

BRIEF-Biotage Q1 operating profit rises to SEK 24 mln

* Q1 operating profit SEK 23.6 mln (18.0)

Source text for Eikon:

Further company coverage:

(Stockholm Newsroom)

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EU mergers and takeovers (April 28)

BRUSSELS, April 28 (Reuters) - The following are mergers

under review by the European Commission and a brief guide to the

EU merger process:

Read more

UPDATE 1-Celgene revenue rises less than expected due to strong dollar

April 28 (Reuters) - U.S. biotechnology company Celgene Corp

reported first-quarter revenue that fell just shy of

analysts estimates due to the stronger dollar, sending the

company's shares down 1.5 percent in premarket trading.

Read more

BRIEF-Meridian Bioscience reports Q2 NON-GAAP EPS $0.24

* Q2 earnings per share view $0.24 -- Thomson Reuters

I/B/E/S

Read more

Bristol raises 2016 forecast after first-quarter earnings beat

April 28 (Reuters) - Bristol-Myers Squibb ratcheted

up its 2016 profit view after trouncing first-quarter sales and

earnings forecasts, driven by demand for its new Opdivo

immuno-oncology drug and its Eliquis blood clot preventer.

Read more

BRIEF-Abbott to acquire St. Jude medical

* Transaction expected to be accretive to abbott's adjusted

earnings per share(1) in first full year after closing and

increasing thereafter

Read more

BRIEF-Hangzhou Liaison Interactive to buy shares of Dehaier Medical Systems

* Says it plans to buy 11.1 million shares in Dehaier

Medical Systems at $1.8 per share

Read more

BRIEF-Beijing Beilu Pharmaceutical plans industry buyout fund worth 610 mln yuan

* Syas it plans to set up industry buyout fund worth 610

million yuan ($94.16 million)

Read more

BRIEF-Dignitana brings DigniCap to three more cities in the U.S.

* Dignitana brings FDA-cleared DigniCap system to three more cities in the U.S.

Read more

OFFICIAL CORRECTION-UBS, MPM team up on $471 mln cancer fund to speed drug development

ZURICH, April 27 (Reuters) - A $471 million UBS

venture fund aims to generate annual returns "north of 10

percent" for its European and Asian investors by financing new

cancer drugs, helping speed them from the lab to the point where

drug companies buy their rights.

Read more

BRIEF-Jilin Aodong Pharma's Q1 net profit down 38.1 pct

April 28 (Reuters) - Jilin Aodong Pharmaceutical Group Co

Ltd

Read more

BRIEF-Feelgood Svenska signs deal with city of Malmo

* Signs deal with city of Malmo

Source text for Eikon:

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BRIEF-Addlife's rights issue fully subscribed

* Rights issue with preferential rights for company's shareholders has been fully subscribed

Read more

UPDATE 1-Sanofi bids $9.3 bln for U.S. cancer drug firm Medivation

PARIS/LONDON, April 28 (Reuters) - French pharmaceuticals

group Sanofi said on Thursday it had made an offer to

buy U.S. cancer treatment firm Medivation in a deal worth about

$9.3 billion, marking its return to the biotech takeover trail.

Read more

Wednesday, April 27, 2016

BRIEF-Brighter to issue 4.6 million shares

* Said on Wednesday made decision to issue 4.6 million shares without preferential rights

for existing shareholders

Read more

BRIEF-Recipharm Q1 operating profit falls

* Recipharm says going forward we expect to see continued

sequential increases in ebitda-margin and significant growth

from announced acquisitions

Source text for Eikon:

Further company coverage:

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BRIEF-Vistin Pharma Q1 EBITDA at 11.0 million Norwegian crowns

* Q1 net profit came in at 6.6 million crowns

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Molecular Partners posts net loss of 4.2 million Swiss francs in Q1 2016

* Phase II strategy for MP0250 laid-out, strategy about

immuno-oncology pipeline disclosed, business and financial

outlook 2016 fully confirmed

Read more

DIARY-Malaysia 2016 corporate earnings

Following is a list of release dates for the quarterly earnings

of some top Malaysia-listed companies.



To submit a date, email: ananthalakshmi.as@tr.com



Company RIC PERIOD DATE

AirAsia Bhd Q1 May 16-20

AMMB Holdings Bhd Q4 May 20-24

Astro Malaysia Holdings Bhd Q1 Jun 14-20

Axiata Group Bhd Q1 May 25

British American Tobacco

Read more

BRIEF-Valeant to name 4 new directors as soon as Friday -CNBC, citing DJ

* Valeant to name 4 new directors as soon as Friday as 5

board members step down; departing directors to include

Valueact's Mason Morfit -CNBC, citing DJ

(Bengaluru Newsroom)

Read more

Valeant to name four new directors as soon as Friday -WSJ

April 27 (Reuters) - Drugmaker Valeant Pharmaceuticals

International Inc is expected to name four new

directors as soon as Friday, the Wall Street Journal reported.

Read more

UPDATE 1-Samsung Biologics plans IPO this year, seen worth as much as $2.6 bln

* Aims to be the world's largest contract manufacturer

(Adds company details, biotech market background)

Read more

Charity urges price cut for pneumonia vaccine for poor children

NEW YORK, April 27 (Thomson Reuters Foundation) - Global

charity Medecins Sans Frontieres delivered a petition with

hundreds of thousands of signatures to pharmaceutical giant

Pfizer Inc on Wednesday, asking the drugmaker to slash the price

of its pneumonia vaccine for poor children.

Read more

BRIEF-Valeant Chairman Robert Ingram also considering leaving the board- CNBC, citing DJ

* Valeant Chairman Robert Ingram also considering leaving

the board- CNBC, citing dow jones

Further company coverage:

Read more

UPDATE 1-Merck sex discrimination case could be collective action -judge

April 27 (Reuters) - A federal judge has granted preliminary

approval for a lawsuit accusing Merck & Co Inc of

underpaying female sales representatives to go forward as a

collective action.

Read more

Samsung Biologics plans to list in S.Korea in 2016

SEOUL, April 28 (Reuters) - Samsung Biologics Co Ltd, the

biopharmaceutical contract manufacturing affiliate of Samsung

Group, said on Thursday that it decided to pursue an

initial public offering in South Korea in 2016.

Read more

UPDATE 3-Ackman, Valeant pledge reforms after spiking drug prices

WASHINGTON/NEW YORK, April 27 (Reuters) - Activist investor

William Ackman promised U.S. lawmakers on Wednesday that he will

urge the board of Valeant Pharmaceuticals to reduce the

high prices of four life-saving drugs that are now at the heart

of two congressional probes.

Read more

BRIEF-Varian Medical Q2 non-GAAP EPS $1.09

* Varian medical systems reports results for second quarter

of fiscal year 2016

Read more

Valeant to pay new CEO Papa base salary of $1.5 mln

April 27 (Reuters) - Drugmaker Valeant Pharmaceuticals

International Inc's new chief executive, Joseph Papa,

will receive a base salary of $1.5 million, the company said in

a filing on Wednesday.

Read more

BRIEF-Ackman to call Valeant board Thursday to discuss drug pricing

April 27 (Reuters) - Valeant Pharmaceuticals International

Inc

Read more

BRIEF-Pra Health Sciences Q1 adj earnings per share $0.55

* Pra Health Sciences, Inc. Reports first quarter 2016

results and updates 2016 guidance

Read more

BRIEF-ADMA Biologics announces proposed public offering of common stock

* Adma Biologics announces proposed public offering of

common stock

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Conmed Corp reports Q1 GAAP loss per share $0.08

* Q1 earnings per share view $0.41 -- Thomson Reuters

I/B/E/S

Read more

BRIEF-Parexel International reports Q3 adj earnings per share $0.89

* Parexel International reports third quarter fiscal year

2016 results

Read more

With more cash, we can eliminate malaria within our lifetime - ex-WHO official

LONDON, April 27 (Thomson Reuters Foundation) - Malaria can

be eliminated soon, but only with much more investment, both to

get rid of the disease and to keep it at bay, a former senior

official of the World Health Organization (WHO) said.

Read more

UPDATE 5-Boston Scientific hits 10-year high on strong results, forecast

* Shares surge 12 pct to 10-year high

(Adds second quarter forecast, updates shares)

Read more

BRIEF-Guerbet Q1 revenue jumps at 183.7 million euro

* Q1 revenue of 183.7 million euro versus 112.2 million euro

($127.0 million) a year ago

Read more

BRIEF-PCAS to change its corporate name

* Produits Chimiques et Auxiliaires de Synthèse has decided to change its corporate name to

PCAS

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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UPDATE 1-Pfizer to pay $784.6 million to resolve Wyeth false claims lawsuit

WASHINGTON, April 27 (Reuters) - Pfizer Inc has

agreed to pay $784.6 million to resolve allegations that Wyeth,

which it acquired in 2009, underpaid drug rebates to Medicaid,

the federal health insurance program, the Justice Department

said Wednesday.

Read more

Fear of Boko Haram deters displaced in Chad from going home - aid agencies

DAKAR, April 27 (Thomson Reuters Foundation) - Fear of new

Boko Haram attacks in the Lake Chad area is discouraging around

100,000 people uprooted by violence from heading home and is

hindering aid operations, agencies said on Wednesday, days after

Chad extended its state of emergency.

Read more

BRIEF-Medical Prognosis Institute and Oncology Venture enter three deals on DRP's

* Says has sold three Drug Response Predictors (DRPs) to Oncology Venture for three new

selected compounds combined with MPI'S DRP for anti-cancer treatment

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Anthem CEO sees need for more changes in Obamacare marketplace structure

* Anthem CEO says it sees need for more changes in

marketplace structure, such as fewer special enrollment

exceptions

Read more

BRIEF-VCA Inc Q1 EPS $0.57

* Q1 revenue $563.4 million versus i/b/e/s view $556.9

million

Read more

BRIEF-Celldex Therapeutics says initiates phase 1/2 study of Glembatumumab Vedotin in squamous cell lung cancer

* Says initiates phase 1/2 study of Glembatumumab Vedotin in

squamous cell lung cancer

Read more

BRIEF-Hualan Biological Engineering's Q1 net profit up 28.6 pct

* Says Q1 net profit up 28.6 percent y/y at 192.4 million

yuan ($29.63 million)

Read more

BRIEF-GSK CEO expects successor to be named towards end of 2016

April 27 (Reuters) - GlaxoSmithKline Chief Executive

Andrew Witty told reporters:

Read more

BRIEF-Amplifon Q1 net profit rises to EUR 8.6 mln

* Q1 revenue 254.5 million euros ($287.66 million) versus 231.3 million euros a year ago

Read more

Health insurer Anthem reports higher revenue on Medicaid enrollments

April 27 (Reuters) - Health insurer Anthem Inc,

which is in the process of buying smaller rival Cigna Corp

, reported a near 6.5 percent rise in quarterly revenue,

as it added more members to its Medicaid plans.

Read more

BRIEF-Bionor Pharma announces departure of CEO

* Said on Tuesday David Horn Solomon will leave his position as Chief Executive Officer of

Bionor Pharma, owing to shareholder led change in company strategy

Read more

Finland's Orion beats market expectations in first quarter

HELSINKI, April 27 (Reuters) - Finnish drug maker Orion

on Wednesday reported better than expected quarterly

results as revenue from its asthma treatment products helped

offset falling sales of its Parkinson's disease drug which faced

increased generic competition.

Read more

BRIEF-Hansa Medical Q1 operating loss widens to SEK 19.9 million

* Q1 net sales 0.5 million Swedish crowns ($61,643.16) versus 3.8 million crowns year ago

Read more

BRIEF-Sobi CEO says currently not looking to sell the company

April 27 (Reuters) - Sobi CEO in news wire call

after Q1 report:

Read more

French and Benelux stocks-Factors to watch on April 27

PARIS, April 27 (Reuters) - Below are company-related news

and stories from French and Benelux media which could have an

impact on the region's markets or individual stocks.

Read more

Tuesday, April 26, 2016

German stocks - Factors to watch on April 27

BERLIN/FRANKFURT, April 27 (Reuters) - The following are

some of the factors that may move German stocks on Wednesday:

Read more

BRIEF-Pixium Vision Q1 operating income at 0.7 million euros

* Q1 operating income amounted to 0.7 million euros, down

31.6 pct year-on-year

Read more

BRIEF-Otsuka Pharmaceutical says FDA issued CRL for co, Proteus Digital Health's digital medicine

* FDA issues complete response letter for digital medicine

new drug application

Read more

HK Exchange says 12 firms buy back shares

HONG KONG, April 27 (Reuters) - The Hong Kong stock exchange said on Wednesday 12 companies

had repurchased their ordinary shares in the market.

The following is a table regarding share buybacks:



Company Name Stock Code Date of No. of Highest Lowest price

Repurchased Securities price per per share

Repurchased share

--- --- ---

Read more

White House urges Congress to move on Zika funding

WASHINGTON, April 26 (Reuters) - Two senior Obama

administration officials wrote congressional leaders on Tuesday

to urge legislation be passed to fund the fight against the Zika

virus, as concerns mount the United States will soon face

locally transmitted cases of the disease.

Read more

UPDATE 2-Edwards raises outlook, plans for valve label expansion

April 26 (Reuters) - Edwards Lifesciences Corp on

Tuesday raised its full-year sales and profit outlook following

strong first-quarter results and said approval for expanded use

of its minimally invasive heart valve implant could come sooner

than previously expected.

Read more

BRIEF-Psychemedics quarterly revenue fell 1 pct to $6.7 mln

* Quarterly earnings per share $0.00

Source text for Eikon:

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UPDATE 4-Cheap oil smudges Exxon's long-held sterling credit rating

April 26 (Reuters) - Exxon Mobil Corp lost its

top-tier credit rating from Standard & Poor's on Tuesday for the

first time in almost 70 years, as slumping crude prices crimp

the oil giant's ability to fund projects and return big amounts

of cash to shareholders.

Read more

BRIEF-Helius Medical Technologies says necessary to re-evaluate warrants' accounting

* Board says necessary to re-evaluate accounting relating to

warrants issued in private placements in april, june, july 2015

Read more

BRIEF-Edwards Lifesciences Q1 adj shr $0.71

* Q1 earnings per share view $0.66 -- Thomson Reuters

I/B/E/S

Read more

BRIEF-ResMed Inc reports Q3 GAAP earnings per share $0.63

* Q3 revenue $453.9 million versus i/b/e/s view $455.9

million

Read more

Deals of the day- Mergers and acquisitions

April 26 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 2000 GMT on Tuesday:

Read more

Edwards Lifesciences raises outlook on strong valve sales

April 26 (Reuters) - Edwards Lifesciences Corp on

Tuesday reported a better-than-expected quarterly profit and

raised its full-year outlook on strong sales of its minimally

invasive heart valve implants.

Read more

BRIEF-Bluelinea FY operating loss narrows to 1.9 million euros

* FY operating loss 1.9 million euros ($2.15 million) versus loss of 2.4 million euros year

ago

Read more

U.S. House Democrats question if Valeant is wrongfully withholding records

WASHINGTON, April 26 (Reuters) - Democrats on a powerful

U.S. congressional panel are questioning whether Canada-based

Valeant Pharmaceuticals may be wrongfully withholding

documents in connection with its ongoing probe into

sky-rocketing drug prices, according to an internal memo seen by

Reuters on Tuesday.

Read more

BRIEF-Euroespes FY net profit up 16 pct at 207,000 euros yoy

* FY revenue up 11.49 percent at 2.9 million euros ($3.3 million) versus 2.6 million euros

year ago

Read more

BRIEF-S&P says Perrigo downgraded to 'BBB-' on weaker-than-expected profits

* Perrigo co. Plc downgraded to 'BBB-' on

weaker-than-expected profits; Outlook stable

Read more

BRIEF-Quantum genomics receives authorisation to begin Phase IIA multicentric European trial

* Regulatory authorisations received in France to begin Phase IIA multicentric European

trial for heart failure

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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BRIEF-Catalyst pharmaceuticals provides regulatory update on Firdapse

* Catalyst pharmaceuticals provides regulatory update on

firdapse

Source text for Eikon:

Further company coverage:

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BRIEF-Durect announces pricing of public offering of common stock

* Durect announces pricing of public offering of common

stock

Read more

BRIEF-Exiqon Q1 EBITDA down at DKK 2.5 million

* Q1 total revenue 39.0 million Danish crowns versus 39.0 million crowns year ago

Read more

UPDATE 2-Lilly earnings fall short, hurt by research spending

April 26 (Reuters) - Eli Lilly and Co on Tuesday

reported lower than expected first quarter earnings due largely

to heavy spending on research, sending its shares 2 percent

lower in premarket trading.

Read more

UPDATE 1-Baxter lifts 2016 adjusted profit forecast after strong quarter

April 26 (Reuters) - Baxter International Inc

reported a better-than-expected quarterly profit and lifted its

adjusted earnings forecast for 2016.

Read more

BRIEF-Harbin Gloria Pharmaceuticals' Q1 net profit up 21.9 pct

* Says Q1 net profit up 21.9 percent y/y at 152.7 million

yuan ($23.51 million)

Read more

Baxter's sales dip 1 pct, hurt by strong dollar

April 26 (Reuters) - Baxter International Inc

reported a near 1 percent fall in first-quarter net sales,

constrained by the dollar's strength.

Read more

BRIEF-Exicure announces dosing of first patient in phase 1 trial

* Exicure announces dosing of first patient in phase 1 trial

for the treatment of chronic plaque psoriasis

Source text for Eikon:

(Bengaluru Newsroom: +1-646-223-8780)

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BRIEF-Guizhou Bailing Group Pharmaceutical's Q1 net profit up 19.7 pct

April 26 (Reuters) - Guizhou Bailing Group Pharmaceutical Co

Ltd

Read more

China to give 2 bln yuan in subsidies to public hospitals in 100 trial cities

BEIJING, April 26 (Reuters) - China will offer 2 billion

yuan, or $308 million, in subsidies to public hospitals in 100

trial cities, the State Council, or cabinet, said in an

announcement on 2016 health care reform goals on Tuesday.

Read more

BRIEF-AstraZeneca, Ironwood agree U.S. licensing agreement

* Agreement includes U.S. rights to zurampic and

lesinurad/allopurinol fixed-dose combination in gout

Read more

BRIEF-Sarepta statement on advisory committee outcome for use of Eteplirsen in treatment of Duchenne muscular dystrophy

* Sarepta issues statement on advisory committee outcome for

use of Eteplirsen in treatment of duchenne muscular dystrophy

Read more

UPDATE 1-Nokia to buy health tracking firm Withings

HELSINKI, April 26 (Reuters) - Finnish mobile network

equipment maker Nokia said on Tuesday it had struck a

deal to buy France's Withings S.A. for 170 million euros ($191

million) in its first move into the market for digital products

that monitor health.

Read more

BRIEF-Pharmaceutical firm Yunnan Baiyao's Q1 net profit up 10.8 pct

* Says Q1 net profit up 10.8 percent y/y at 621.9 million

yuan ($95.79 million)

Read more

BRIEF-Xvivo Perfusion Q1 EBITDA up at SEK 7.3 million

* Q1 operating income before depreciation and amortization (EBITDA) excluding one-time

expenses amounted to 7.3 million Swedish crowns ($897,357), corresponding to EBITDA margin of 22

percent, versus an EBITDA of 4.5 million crowns a year ago

Read more

BRIEF-Probi signs extensive primary care distribution agreement with Ipsen

* Probi and Ipsen sign extensive primary care distribution agreement for probiotic LP299V,

Lactobacillus plantarum 299v

Read more

BRIEF-Ipsen partner Exelixis obtains FDA approval of CABOMETYX tablets

* Announces that its partner Exelixis obtained FDA

approval of CABOMETYX (cabozantinib) tablets for patients with

advanced renal cell carcinoma who have received prior

anti-angiogenic therapy

Source text for Eikon:

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(Gdynia Newsroom)

Read more

BRIEF-BioInvent says swings to slim Q1 profit

* Says net sales for january - march 2016 amounted to SEK 29

(0.6) million

Read more

Monday, April 25, 2016

Malaria deaths rising in Angola as health crisis spreads

LUANDA, April 26 (Reuters) - Deaths from malaria in Angola

this year look set to outstrip 2015 as a health crisis that

includes one of the country's worst yellow fever outbreaks in

decades spreads, the World Health Organisation said.

Read more

Bayer Q1 adj EBITDA up 16 percent on pharmaceuticals

FRANKFURT, April 26 (Reuters) - Germany drugmaker Bayer

reported 15.7 percent higher underlying core earnings

for the first quarter, boosted by prescription drugs such as eye

treatment Eylea.

Read more

Singapore March factory output dips 0.5 pct y/y, less than expected

SINGAPORE, April 26 (Reuters) - Singapore's industrial

production in March fell less than expected from a year earlier

due to a surge in pharmaceuticals, data showed on Tuesday.

Manufacturing output fell 0.5 percent from a year earlier in

March, data from the Singapore Economic Development Board

showed. The median forecast in a Reuters survey was for a drop

of 2.7 percent.

On a month-on-month and seasonally adjusted basis, factory

output rose 1.0 percent in March, matching the median for

Read more

German stocks - Factors to watch on April 26

FRANKFURT/BERLIN, April 26 - The following are some of the

factors that may move German stocks on Tuesday:

Read more

Alere receives default notice from bondholder group - Bloomberg

April 25 (Reuters) - Alere Inc received a notice of

default from a group of its bondholders after the diagnostics

company delayed filing its 2015 annual report in March,

Bloomberg reported Monday.

Read more

BRIEF-Alere received notice of default from group of bondholders - Bloomberg

* Alere Inc received a notice of default from a group of

bondholders after co delayed filing its 2015 financial statement

- Bloomberg, citing sources

Source text : (http://bloom.bg/1TtAPkC)

Further company coverage:

Read more

BRIEF-MiMedx Group Q1 adjusted earnings per share $0.04

* Q1 earnings per share view $0.05 -- Thomson Reuters

I/B/E/S

Read more

UPDATE 6-Valeant names Papa CEO after he resigns from Perrigo

April 25 (Reuters) - Former Perrigo Co Plc head

Joseph Papa was named Chief Executive Officer at Valeant

Pharmaceuticals International on Monday, a role in

which investors said he should focus on returning the company to

growth.

Read more

BRIEF-Verisk Analytics signs definitive agreement to sell its healthcare services business to Veritas Capital for $820 mln

* Verisk analytics, inc., signs definitive agreement to sell

its healthcare services business to Veritas Capital for $820

million

Read more

BRIEF-Perrigo enters into amendment to employment agreement in connection with Joseph Papa's resignation

* In connection with Papa's resignation, he and co, and

Perrigo Michigan entered into an amendment to employment

agreement

Read more

Canada confirms first sexually transmitted Zika case

WINNIPEG, Manitoba, April 25 (Reuters) - An Ontario resident is Canada's first confirmed case of a Zika virus infection that was contracted locally through sex, health officials said on Monday.

Read more

BRIEF-Transition Therapeutics says dosing of first patient in Phase 2 study of drug candidate TT701

* Transition therapeutics announces dosing of first patient

in phase 2 study of drug candidate tt701

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Txcell and Ospedale San Raffaele to develop CAR-Tregs in Lupus Nephritis

* Txcell and Ospedale San Raffaele launch collaboration for the development of CAR-Tregs in

Lupus Nephritis

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Produits Chimiques Auxiliaires Et De Synthese signs deal with Abivax

April 25 (Reuters) - Produits Chimiques Auxiliaires Et De

Synthese Sa :

Read more

BRIEF-Zimmer Biomet enters into agreement to buy Cayenne Medical

* Zimmer Biomet enters into definitive agreement to acquire

cayenne medical

Read more

BRIEF-Trovagene appoints Bill Welch as CEO

* Trovagene inc says matthew posard , company's chief

commercial officer, has left company.

Read more

BRIEF-Guizhou Yibai Pharmaceutical's share trade to resume on April 26

Further company coverage:

(Reporting by Hong Kong newsroom)

Read more

U.S. FDA panel meets to discuss Sarepta muscular dystrophy drug

April 25 (Reuters) - Hundreds of patients and advocates

packed a hotel ballroom in Hyattsville, Maryland on Monday to

try to persuade advisors to the U.S. Food and Drug

Administration to support approval of an experimental drug to

treat Duchenne muscular dystrophy.

Read more

BRIEF-Zimmer Biomet to acquire Cayenne Medical

* Entered into a definitive agreement to acquire Scottsdale,

Arizona-based Cayenne Medical, Inc

Read more

BRIEF-DIOD recommends no FY 2015 dividend

* Says board recommends no FY 2015 dividend

Source text: http://bit.ly/1TsIGPi

Read more

BRIEF-Tesaro announces submission of investigational new drug application

* Tesaro Announces Submission Of Investigational New Drug

Application For Anti Tim-3 antibody tsr-022 to the u.s. Fda

Read more

BRIEF-Fibrocell receives orphan drug designation for FCX-013

* Sats receives orphan drug designation from the FDA for for

FCX-013 for the treatment of localized scleroderma

Read more

BRIEF-Perkinelmer sells NTD laboratory services business to Eurofins Scientific

* PerkinElmer sells NTD laboratory services business to

Eurofins Scientific

Read more

BRIEF-Perrigo says Joseph C. Papa resigns as chairman and CEO

* Perrigo appoints John T. Hendrickson as chief executive

officer, provides preliminary first-quarter 2016 selected

financial results, and updates full-year 2016 guidance

Read more

Deals of the day-Mergers and acquisitions

April 25 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1000 GMT on Monday:

Read more

BRIEF-Beijing SL Pharmaceutical's Q1, 2015 net profit down

* Says Q1 net proit down 16.8 percent y/y at 149.1 million

yuan ($22.96 million)

Read more

Novartis discussing Roche stake sale, but not imminent -sources

LONDON/ZURICH, April 25 (Reuters) - Novartis is

discussing options with banks for selling its 13.5 billion Swiss

franc ($13.8 billion) stake in rival Roche, though a

sale is not imminent, according to two people familiar with the

situation.

Read more

BRIEF-Philips says Lighting unit IPO/sale proceeds likely to be used in blended form - conf call

* Says proceeds from IPO or sale of lighting division will

likely be used in a blended form - conference call

Read more

Covestro on track to reach yr-earlier EBITDA levels in Q2 -CFO

FRANKFURT, April 25 (Reuters) - Covestro, the

plastics and chemicals maker that parent Bayer plans

to divest, is confident that second-quarter earnings before

interest, taxes, depreciation and amortisation (EBITDA) will

reach year-earlier levels, its finance chief said.

Read more

Philips CEO says Lumileds division performance to improve in H2

AMSTERDAM, April 25 (Reuters) - The performance of Philips'

up-for-sale Lumileds lighting components division is

expected to improve in the second part of 2016, CEO Frans van

Houten said on Monday.

Read more

BRIEF-Merck's phase iii tailor landmark study demonstrates significant benefits of Erbitux in combination with FOLFOX over FOLFOX alone

* Says phase iii tailor landmark study demonstrates

significant benefits of erbitux in combination with FOLFOX over

FOLFOX alone

Read more

Swiss stocks - Factors to watch on April 25

ZURICH, April 25 (Reuters) - The Swiss blue-chip SMI

was seen opening barely changed at 8110 points on Monday,

according to premarket indications by bank Julius Baer

.

Read more

BRIEF-Revenio Q1 net sales rises to 5.2 million euros

* Q1 net sales 5.2 million euros ($5.85 million) versus 4.6 million euros year ago

Read more

Sunday, April 24, 2016

BRIEF-Koninklijke Philips Q1 comparable sales up 3 pct at EUR 5.5 BLN

* Q1 adjusted EBITA amounted to 374 million euros ($420.34

million), or 6.8 percent of sales, compared to 6.1 percent of

sales in Q1 2015

Read more

BRIEF-UCB Q1 revenue rises to 991 million euros

* Q1 revenue 991 million euros versus 895 million euros year

ago

Read more

DIARY-Malaysia 2016 corporate earnings

Following is a list of release dates for the quarterly earnings

of some top Malaysia-listed companies.



To submit a date, email: ananthalakshmi.as@tr.com



Company RIC PERIOD DATE

AirAsia Bhd Q1 May 16-20

AMMB Holdings Bhd Q4 May 20-24

Astro Malaysia Holdings Bhd Q1 Jun 14-20

Axiata Group Bhd Q1 May 25

British American Tobacco

Read more

BRIEF-Joincare Pharma's Q1 net profit down 10.7 pct y/y

April 25 (Reuters) - Joincare Pharmaceutical Group Industry

Co Ltd

Read more

UPDATE 1-Iraq signs strategic agreement with GE to boost power grid

BAGHDAD, April 24 (Reuters) - Iraq's Oil Ministry said on

Sunday it had signed a long-term "strategic framework agreement"

with General Electric which comprised several projects to

boost national power resources.

Read more

Once a symbol of decline, Pennsylvania tests limits of Trump's appeal

BETHLEHEM, Pa., April 24 (Reuters) - With a rusting steel

mill in its center, this Pennsylvania city would seem fertile

ground for Donald Trump's campaign and its vision of a declining

America that only he can fix.

Read more

Iraq signs strategic agreement with GE to boost power grid

BAGHDAD, April 24 (Reuters) - Iraq's Oil Ministry said on

Sunday it had signed a long-term "strategic framework agreement"

with General Electric which comprised several projects to

boost national power resources.

Read more

Nearly 50 starving monkeys rescued in South Africa by animal rights group

MULDERSDRIFT, South Africa, April 23 (Reuters) - Close to 50

starved and sick monkeys were rescued from filthy living

conditions in a South African private zoo on Saturday, and were

whisked away to a care facility, an international animal rights

group said.

Read more

Saturday, April 23, 2016

Valeant gets additional notices of default from bondholders

April 22 (Reuters) - Canadian drugmaker Valeant

Pharmaceuticals International Inc said it received

additional notices of default from its bondholders as a result

of a delay in filing its annual report.

Read more

Friday, April 22, 2016

BRIEF-Natus Medical says CEO James Hawkins FY 2015 total compensation $4.5 mln vs $3.8 mln in FY 2014

* Says CEO James B. Hawkins FY 2015 total compensation $4.5

mln vs $3.8 mln in FY 2014 - sec filing

Source text: http://1.usa.gov/1SzHsS0

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

Read more

BRIEF-Intellia Therapeutics appoints Perry Karsen as chairman of board

* Intellia therapeutics appoints perry karsen as chairman of

its board of directors

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-Mettrum files preliminary short form prospectus for $7.5 mln bought deal offering of common shares

* Mettrum announces filing of preliminary short form

prospectus for $7.5 million bought deal offering of common

shares

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

REFILE-China to ratify Paris climate change deal by September: envoy

UNITED NATIONS, April 22 (Reuters) - China, one of the

world's top emitters of greenhouse gases, pledged on Friday to

ratify the Paris deal to slow climate change by September,

China's Vice Premier Zhang Gaoli said on Friday.

Read more

BRIEF-Unitedhealth Group CEO 2015 total compensation $14.5 mln

* CEO Stephen J. Hemsley's 2015 total compensation was $14.5

million versus $14.9 million in 2014 - SEC filing

Read more

U.S. FAA orders fix for GE engines on up to 150 Boeing 787 jets

NEW YORK, April 22 (Reuters) - The U.S. aviation regulator

on Friday ordered an urgent fix for General Electric

engines on up to 150 Boeing 787 Dreamliners, a step to

avoid conditions that can cause an engine failure in icy

conditions.

Read more

CORRECTED-Disgruntled investors flex vote muscle on UK executive pay

LONDON, April 22 (Reuters) - Change the way you pay or risk

losing your jobs, corporate governance watchdogs have warned the

boards of Britain's top companies, as investors call for a

reality check on salaries.

Read more

U.S. agencies issues rules to protect workers from Zika

CHICAGO, April 22 (Reuters) - U.S. health and safety officials issued new guidelines on Friday to help protect workers from exposure to Zika, a mosquito-borne and sexually-transmitted virus that causes the birth defect microcephaly and other neurological disorders.

Read more

U.S. FDA staff sets voting questions for Sarepta's muscle drug

April 22 (Reuters) - U.S. Food and Drug Administration staff

on Friday formulated voting questions on Sarepta Therapeutics

Inc's muscle wasting drug, ahead of a highly

anticipated meeting of independent panel of experts on Monday to

review the drug.

Read more

BRIEF-FDA accepts Lundbeck resubmission of NDA for Carnexiv

* FDA accepts Lundbeck resubmission of new drug application

for Carnexiv

Read more

BRIEF-aap implantate posts 2015 EBITDA loss of 1.9 mln euros

* Annual financial statements 2015: sales at 28 million

euros ($31.48 million) within the guidance

Read more

UPDATE 1-U.S. FDA proposes ban on certain electrical stimulation devices

April 22 (Reuters) - The U.S. Food and Drug Administration

on Friday proposed a ban on electrical stimulation devices

(ESDs) that are used to curb individuals from engaging in

self-injurious or aggressive behavior, saying they pose an

"unreasonable and substantial" risk to public health.

Read more

BRIEF-Corelens to supply materials used for treatment of cataract

* Receives signed agreement with a public hospital for the

delivery of materials used for treatment of cataract

Read more

BRIEF-Cipher Pharmaceuticals announces retirement of CFO Norm Evans

* Cipher Pharmaceuticals announces retirement of CFO Norm

Evans

Read more

Dividend recap deals return as junk bonds heat up

NEW YORK, April 22 (IFR) - In another sign that the US junk

bond market has turned the corner, syndicate desks are prepping

a number of deals that pay juicy dividends to private equity

sponsors.

Read more

Mexico explores regulating opium to fight drug violence

MEXICO CITY, April 22 (Reuters) - Mexico's government has

explored regulating poppy production to make pharmaceutical

opiates like morphine in an effort to weaken heroin-smuggling

gangs, according to two sources with knowledge of the

government's thinking.

Read more

China to ratify Paris climate change deal by September: envoy

UNITED NATIONS, April 22 (Reuters) - China, one of the

world's top emitters of greenhouse gases, pledged on Friday to

ratify the Paris deal to slow climate change by September, a

senior Chinese envoy said on Friday.

Read more

UPDATE 2-GE profit tops estimates but organic revenue falls 1 percent

NEW YORK, April 22 (Reuters) - General Electric Co

reported a higher-than-expected first-quarter profit on Friday,

but a closely watched revenue measure declined, raising

questions about the company's full-year target.

Read more

CANADA STOCKS-Futures rise on higher oil, positive data

April 22 (Reuters) - Stock futures pointed to a higher start

for Canada's main stock index on Friday as oil prices hovered

near $45 per barrel and after Canada's retail sales and

inflation data.

Read more

BRIEF-Mevis Medical Solutions FY net income up to EUR 6.7 mln

* Publishes figures for fiscal year 2015 and guidance for 2016

Read more

BRIEF-Intrexon provides update on recent stock trading activity

* On thursday, a report regarding company, its subsidiaries

and its chairman and ceo was published a financial blog

Read more

BRIEF-GE posts Q1 operating earnings per share $0.06

* Q1 earnings per share view $0.19, revenue view $27.62

billion -- Thomson Reuters I/B/E/S

Source text (http://invent.ge/1MMuWQ1)

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

BRIEF-GE reaffirms 2016 EPS guidance of $1.45-$1.55

* Reaffirms 2016 industrial operating + verticals EPS

guidance $1.45-$1.55

Read more

UPDATE 1-UK Stocks-Factors to watch on April 22

April 22 (Reuters) - Britain's FTSE 100 index is seen opening lower

32 points, or 0.5 percent, on Friday, according to financial bookmakers, with

futures down 0.4 percent ahead of the cash market open. For more on the

factors affecting European stocks, please click on

Read more

BRIEF-Lidds Q1 pre-tax loss narrows to SEK 1.5 million

* Q1 pre-tax loss 1.5 million Swedish crowns ($185,000)

versus loss 2.2 million crowns year ago

Source text for Eikon:

Read more

BRIEF-Cytotools unit signs contracts for production with German manufacturer

* Dermatools Biotech identifies new manufacturers for drug DermaPro, thereby creating the

basis for the repetition of the phase III clinical study

Read more

Thursday, April 21, 2016

BRIEF-Sobi says signs licensing agreement with Affibody for IL-1

* Says exercised its option to sign a licensing agreement

with Swedish biotech company Affibody AB for the development of

novel treatments for inflammatory diseases where interleukin-1

(IL-1) is involved

Source text for Eikon:

Further company coverage:

(Stockholm Newsroom)

Read more

Swiss stocks - Factors to watch on April 22

ZURICH, April 22 (Reuters) - The Swiss blue-chip SMI

was seen opening 0.17 percent lower at 8,145.7 points on Friday,

according to premarket indications by bank Julius Baer

.

Read more

BRIEF-BB Biotech Q1 net result swings to loss of CHF 1.2 billion

* Reports a net loss of 1.2 billion Swiss francs ($1.23

billion) for Q1 of 2016 compared to a net profit of 379 million

Swiss francs for same period last year

Read more

UK Stocks-Factors to watch on April 22

April 22 (Reuters) - Britain's FTSE 100 index is seen opening down

32 points, or 0.5 percent, on Friday, according to financial bookmakers. For

more on the factors affecting European stocks, please click on

Read more

PRESS DIGEST- Financial Times - April 22

April 22 (Reuters) - The following are the top stories in

the Financial Times. Reuters has not verified these stories and

does not vouch for their accuracy.

Read more

BRIEF-Valeant seeks to name Perrigo's Joseph Papa to be new CEO- CNBC citing DJ

* Valeant Pharmaceuticals International seeks to name

Perrigo's Joseph Papa to be new CEO - CNBC citing DJ

Read more

UK agency backs cancer drug after Sanofi cuts price

LONDON, April 22 (Reuters) - Britain's healthcare cost

watchdog NICE said on Friday it had changed its mind and decided

to recommend Sanofi's prostate cancer drug Jevtana

after the French company agreed to a further discount.

Read more

BRIEF-Human Longevity Inc. announces 10 year deal with Astrazeneca

* Human longevity Inc announces 10 year deal with

Astrazeneca to sequence and analyze patient samples from

Astrazeneca clinical trials

Read more

BRIEF-Biomarin enrolls first patient in early study of BMN 250 for sanfilippo B syndrome

* Biomarin enrolls first patient in phase 1/2 trial of NAGLU

fusion protein BMN 250 for treatment of MPS IIIB (sanfilippo B

syndrome)

Read more

BRIEF-Humana sets quarterly cash dividend of $0.29/share

* Sets quarterly cash dividend of $0.29per share

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

Read more

BRIEF-Healthverity, Inc. says it has sold $7.2 mln in equity financing - SEC Filing

* Healthverity, Inc. says it has sold $7.2 mln in equity

financing - SEC Filing

Read more

Fitch Affirms Owens & Minor at 'BBB-'; Outlook Stable

(The following statement was released by the rating agency)

CHICAGO, April 21 (Fitch) Fitch Ratings has affirmed the ratings

of Owens &

Minor, Inc. (NYSE: OMI), including the long-term Issuer Default

Rating (IDR), at

'BBB-'. The Rating Outlook is Stable.

A full list of rating actions, which apply to approximately $580

million at Dec.

31, 2015, follows at the end of this release.

KEY RATING DRIVERS

Strong Market Share: OMI holds a strong share of the steady and

oligopolistic

market for the di

Read more

BRIEF-Blackstone said in takeover talks with Concordia Healthcare- StreetInsider citing Bloomberg

* Blackstone Said In Takeover Talks With Concordia

Healthcare - Streetinsider citing bloomberg

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

Read more

Gap in death rates between rich and poor young Americans narrows -study

WASHINGTON, April 21 (Reuters) - Death rates for U.S.

infants, children, teenagers and young adults are falling,

particularly among those in poor regions, likely due to social

policies that have helped the most disadvantaged families,

researchers said on Thursday.

Read more

BRIEF-Nexstim's Janne Huhtala steps down as CEO

* Martin Jamieson, Nexstim's chairman, will assume position of CEO

Read more

UPDATE 3-Cost cutting helps Biogen top Wall Street estimates for quarter

* 1st-qtr profit $4.79/shr vs est. $4.47

(Adds company, analyst comment, share move)

Read more

Walgreens, Duane Reade settle NY overcharge probe

April 21 (Reuters) - Walgreen Co agreed to pay $500,000 and

reform its advertising practices to settle allegations its

Walgreens and Duane Reade stores in New York routinely

overcharged consumers and tricked them into thinking they were

getting great deals.

Read more

Deals of the day- Mergers and acquisitions

April 21 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1400 GMT on

Thursday:

Read more

BRIEF-Ultragenyx reports positive interim data from Phase 2 study of KRN23

* Reports positive interim data from Phase 2 study of KRN23

for the treatment of tumor-induced osteomalacia

Read more

BRIEF-MGT Capital says board exploring strategic alternatives

* Mgt capital investments, inc. Reports 2015 consolidated

financial results

Read more

Zika, dengue fever pose "immediate threat" in quake-hit Ecuador-charity

LONDON, April 21 (Thomson Reuters Foundation) -

M osquito-borne diseases including the Zika virus and dengue

fever pose an "immediate threat" to survivors of the devastating

earthquake that hit Ecuador four days ago, an international

charity said on Thursday.

Read more

BRIEF-FDA staff maintains negative outlook on Sarepta's DMD drug

* FDA staff says it does not agree with Sarepta's

characterization of inaccuracies in the initial FDA briefing

document

Read more

BRIEF-Hologic announces FDA clearance of Affirm Prone Biopsy System

* announces FDA clearance and commercial availability Of

Affirm Prone Biopsy System, First 2d/3d Imaging Guided

dedicated prone biopsy system

Read more

IHH Healthcare Berhad buys hospitals in Bulgaria

SOFIA, April 21 (Reuters) - Malaysia-based IHH Healthcare

Berhad is to buy Bulgaria's Tokuda Hospital in a deal

that will help to make it the biggest private healthcare

provider in the Balkan country, the company said on Thursday.

Read more

BRIEF-PDL Biopharma says CEO John Mclaughlin's 2015 compensation was $3.9 mln

* Says CEO John Mclaughlin's 2015 total compensation was

$3.9 million versus $4.1 million in 2014 - SEC filing

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1 646 223 8780)

Read more

BRIEF-Huapont Life Sciences' 2015 net profit up 48.3 pct

* Says 2015 net profit up 48.3 percent y/y at 636.6 million

yuan ($98.29 million)

Read more

BRIEF-Biosynex FY net loss narrows to 0.33 million euros

* FY net loss EUR 0.33 million ($372,867.00) versus loss of

EUR 1.4 million year ago

Read more

BRIEF-Russia's MD Medical Group Q1 total deliveries 1,560, up 18 percent y-o-y

* Says in Q1 total deliveries increased 18 percent y-o-y to

1,560

Read more

BRIEF-Novartis sees 2016 Entresto sales of about $200 mln

* Says expects 2016 entresto sales of about $200 million

Source text for Eikon:

Further company coverage:

(Reporting by John Miller)

Read more

BRIEF-Kancera is to acquire Fractalkine project

* Payment for Fractalkine project to Acturum Life Science AB is to be carried in three steps

with total of 6 million shares

Read more

Wednesday, April 20, 2016

BRIEF-Fibrogen says phase 2 data show Roxadustat corrected Anemia in chronic kidney disease patients before intervention with dialysis

* Promising phase 2 data show Roxadustat corrected Anemia in

chronic kidney disease patients before intervention with

dialysis

Read more

BRIEF-THERAMetrics posts FY net loss of 8.5 million euros

* Generated revenues of 13.8 million euros ($15.58 million)

and net loss of 8.5 million euros for year ended Dec. 31, 2015,

compared to revenues of 16.2 million euros and net loss of 10.2

million euros for year ended Dec. 31, 2014

Read more

PRESS DIGEST- British Business - April 21

April 21 (Reuters) - The following are the top stories on

the business pages of British newspapers. Reuters has not

verified these stories and does not vouch for their accuracy.

Read more

BRIEF-Helix Biopharma says Patrick Frankham appointed COO

* Patrick frankham appointed chief operating officer

Source text for Eikon:

Further company coverage:

Read more

PRESS DIGEST- Financial Times - April 21

April 21 (Reuters) - The following are the top stories in

the Financial Times. Reuters has not verified these stories and

does not vouch for their accuracy.

Read more

BRIEF-TearLab says estimates Q1 total revenue will be about $6.8 mln

* TearLab announces first quarter 2016 preliminary financial

estimates

Read more

BRIEF-American Renal Associates Holdings announces pricing of IPO

* American renal associates holdings, inc. Announces pricing

of initial public offering

Read more

BRIEF-Transenterix says FDA has determined that Surgibot(tm) System does not meet criteria for substantial equivalence

* Transenterix receives response from the fda on surgibot

510(k) submission

Read more

BRIEF-Hemostemix announces non-brokered private placement

* Says non-brokered private placement offering, which will

consist of issuance of up to 12,500,000 units at of $0.40 per

unit

Source text for Eikon:

Further company coverage:

(Bengaluru Newsroom: +1-646-223-8780)

Read more

Singapore slams calls for 'soft approach' to drugs at UN meeting



Read more

BRIEF-Stryker reports Q1 adjusted earnings per share $1.24

* Now expect 2016 adjusted net earnings per diluted share to

be in range of $5.65-$5.80, compared to our prior guidance of

$5.57 - $5.77

Read more

Fitch: Senior U.S. CLO Notes Still Insulated From Downgrades

(The following statement was released by the rating agency)

Link to Fitch Ratings' Report: U.S. CLO Index: Par and OC

Cushions Continue to

Decline in U.S. CLOs

https://www.fitchratings.com/creditdesk/reports/report_frame.cfm?rpt_id=880263

CHICAGO, April 20 (Fitch) Fewer U.S. CLOs are escaping the

rising number of

defaulted issuers, though Fitch rated 'AAA' tranches should

remain shielded from

potential downgrades, according to Fitch Ratings in its latest

U.S. CLO index.

Approximately 70% of 2

Read more

What to Watch in the Day Ahead - Thursday, April 21

(The Day Ahead is an email and PDF publication that includes the day's major stories and

events, analyses and other features. To receive The Day Ahead, Eikon users can register at

. Thomson One users can register at RT/DAY/US. All times in ET/GMT)

Alphabet Inc is expected to report a rise in first-quarter revenue that is likely to beat

analysts average estimate, according to Thomson Reuters StarMine data. Investors will be looking

for continued growth at Alphabet's Google unit, which has

Read more

REFILE-UPDATE 2-Heart failure devices pump up St. Jude's profit, revenue

April 20 (Reuters) - St. Jude Medical Inc reported

better-than-expected quarterly results helped by strong heart

failure device sales and said it was making progress in getting

its pacemaker and defibrillator business back on track.

Read more

BRIEF-AmpliPhi Biosciences provides update on phage therapy Phase I trial

* AmpliPhi Biosciences provides update on Phase I trial:

phage therapy well tolerated in first cohort

Read more

BRIEF-PCAS Q1 revenue up at 45.3 million euros

April 20 (Reuters) - Produits Chimiques Auxiliaires Et De Synthese SA :

Read more

BRIEF-Genticel announces additional results at 12 months for phase 2 of GTL001

* Announces additional results at 12 months for phase 2 of

GTL001

Source text: http://bit.ly/1YH6vUR

Further company coverage:

(Gdynia Newsroom)

Read more

BRIEF-Neptune announces $4 million term loan financing

April 20 (Reuters) - Neptune Technologies & Bioressources

Inc

Read more

UPDATE 1-Canada plans marijuana decriminalization by spring 2017 -minister

TORONTO, April 20 (Reuters) - Canada's Liberal government

will introduce legislation to decriminalize and regulate

recreational marijuana in spring 2017, Health Minister Jane

Philpott said on Wednesday.

Read more

BRIEF-American Renal Associates sees IPO of 7.5 mln shares priced at $20-$23 each

* American Renal Associates Holdings Inc sees IPO of 7.5 mln

shares of its common stock priced between $20 $23 each - SEC

filing

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BRIEF-Pfizer Canada says partnered with Rexall in new service called OneStopMeds

* Partnered with Rexall in service called OneStopMeds to

improve medication adherence for patients taking multiple

chronic medications

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BRIEF-Cytrx to present new clinical data on its cancer drug

* Cytrx to present updated aldoxorubicin clinical trial data

at the American Society of Clinical Oncology Annual Meeting in

June 2016

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BRIEF-VolitionRx says diagnostic test detected 71 pct of early stage I prostate cancer cases

* VolitionRx announces study results showing NUQ blood test

detects prostate cancer early with significantly higher accuracy

than PSA test

Read more

BRIEF-Owens & Minor Distribution sees FY 2016 adj EPS $2.00 to $2.05

* Distribution agreement between Owens & Minor and a large

national healthcare provider customer will not be renewed; O&M

reaffirms financial outlook for 2016

Read more

BRIEF-Biomarin provides preliminary data on first 8 patients in Hemophilia A gene therapy program

* Biomarin provides encouraging preliminary data on first 8

patients in hemophilia a gene therapy program

Read more

Medical device maker St. Jude reports 7.6 pct rise in revenue

April 20 (Reuters) - St. Jude Medical Inc reported a

7.6 percent rise in quarterly revenue, helped by higher sales in

its heart failure and neuromodulation businesses.

Read more

BRIEF-Axsome therapeutics gets pre-ind guidance from FDA for AXS-05

* Ind guidance from fda for AXS-05 for agitation in patients

with alzheimer's disease

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BRIEF-Aralez says conducted bioequivalence studies comparing Aspirin from old and new suppliers

* Conducted human bioequivalence studies comparing aspirin

drug manufactured from original aspirin supplier to new primary

aspirin supplier

Read more

BRIEF-Acorda announces results from mid-phase clinical trial of CVT-301

* Acorda Announces Results From Phase 2b Clinical Trial Of

CVT 301 for treatment of off periods in parkinson's disease

published in movement disorders

Read more

BRIEF-Feelgood Svenska proposes Göran Hägglund as chairman

April 20 (Reuters) - Feelgood Svenska publ AB :



* Proposes Göran Hägglund as new chairman



* Jan-Erik Karlsson declined re-election as chairman



Source text for Eikon:



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BRIEF-Telemedycyna Polska March 2016 revenue down 20.7 pct yoy

* March 2016 revenue 404,400 zlotys ($106,978), down 20.7

percent year on year

Read more

BRIEF-KNF approves Airway Medix's prospectus for WSE's main market listing

* Said on Tuesday that it approved prospectus submitted by

Airway Medix SA related to plans of listing of series A

and B shares on regulated market of the Warsaw Stock Exchange

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BRIEF-Oculus Innovative Sciences receives U.S. FDA approval for Lasercyn

* Oculus Innovative Sciences receives U.S. FDA approval for Lasercyn(tm) for use following

laser procedures, microdermabrasions and chemical peels

Read more

Nestle extends pharma push with new bet on gut drugs

April 20 (Reuters) - Nestle has extended its push

into medicine with a small investment in a biotech company

developing a drug designed to fight inflammatory bowel disease

by restoring a healthy bacteria balance in the gut.

Read more

BRIEF-Bio-Gate fully acquires subsidiary BioEpiderm

* Acquisition of minority interests by way of capital

increase

Read more

BRIEF-Cantargia raises SEK 31.4 mln through exercise of warrants

* Cantargia raises 31.4 million Swedish crowns through

exercise of warrants of series TO 1 and TO 3

Read more

BRIEF-Diamyd Medical increases investment in Cellaviva

* Says increases strategic investment in the stem cell company Cellaviva

Read more

Tuesday, April 19, 2016

BRIEF-Formycon FY net profit at 0.57 million euros

* Increased its turnover in 2015 by 34 percent compared to

previous year, from 12.58 million euros ($14.28 million) to 16.9

million euros

Read more

Barco Q1 sales up on strong healthcare, enterprise units

BRUSSELS, April 20 (Reuters) - Belgian digital display

company Barco said on Wednesday its order book and

quarterly sales had increased compared to the same period last

year with growth in its units making products for hospitals and

control rooms.

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PRESS DIGEST- British Business - April 20

April 20 (Reuters) - The following are the top stories on

the business pages of British newspapers. Reuters has not

verified these stories and does not vouch for their accuracy.

Read more

UPDATE 2-Intuitive Surgical boosts procedure growth forecast

April 19 (Reuters) - Intuitive Surgical Inc on

Tuesday reported better-than-expected first-quarter profit on

expanded use of its da Vinci robots in U.S. general surgeries

such as hernia repair, and it raised its full-year outlook for

procedure growth.

Read more

Global HIV drive hampered without drugs for "neglected" West and Central Africa

DAKAR, April 20 (Thomson Reuters Foundation) - A global

drive to help curb the HIV epidemic by 2020 will fail unless

millions of people with the virus in West and Central Africa

receive life-saving drugs, Medecins Sans Frontieres (MSF) said

on Wednesday.

Read more

UnitedHealth's Obamacare exit adds pricing pressure on rivals

NEW YORK, April 19 (Reuters) - UnitedHealth Group Inc's

decision to exit most of its Obamacare health insurance

exchanges next year means rivals will need to raise prices

further to prop up an unprofitable business, healthcare analysts

and policy experts said on Tuesday.

Read more

UPDATE 1-U.S. pledges $40 mln to countries affected by Boko Haram

YAOUNDE, April 19 (Reuters) - The United States will give

$40 million in humanitarian assistance to countries bordering

Lake Chad fighting Islamist militant group Boko Haram, U.S.

ambassador to the United Nations Samantha Power said on Tuesday.

Read more

BRIEF-Corvus Pharmaceuticals announce results of preclinical studies

* Corvus Pharmaceuticals announces results of preclinical

studies demonstrating enhanced immune responses and anti-tumor

activity with CPI-444, an investigational immuno-oncology

therapy

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BRIEF-Supernus Pharmaceuticals CEO 2015 total compensation $3.2 mln

* CEO Jack A. Khattar's 2015 total compensation was $3.2

million versus $1.7 million in 2014 - SEC filing

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Intuitive Surgical boosts outlook for 2016 procedure growth

April 19 (Reuters) - INTUITIVE SURGICAL RAISES OUTLOOK FOR

2016 PROCEDURE GROWTH TO RANGE OF 12-14 PERCENT

INTUITIVE SURGICAL PREVIOUSLY FORECAST 2016 PROCEDURE GROWTH AT

9-12 PERCENT

INTUITIVE SAYS INCREASE DUE TO FAVORABLE U.S. PROSTATE,

GYNECOLOGICAL SURGERY OUTLOOK

(Reporting by Susan Kelly in Chicago)

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Express Scripts says Anthem negotiated in bad faith -court filing

April 19 (Reuters) - Pharmacy benefit manager Express

Scripts Holding Co has accused Anthem Inc of

negotiating their contract in bad faith and is seeking a court

order that the health insurer has no right to demand lower drug

prices.

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UPDATE 3-J&J shares hit new high on strong drug sales, weaker dollar

April 19 (Reuters) - Johnson & Johnson beat

quarterly earnings forecasts on strong prescription drug revenue

and a weakening dollar, and it reassured investors that it did

not expect its blockbuster Remicade arthritis drug to face U.S.

competition this year.

Read more

UPDATE 1-UN reviews war on drugs amid global push for liberalization

UNITED NATIONS, April 19 (Reuters) - The U.N. General

Assembly gathered on Tuesday to rethink global strategy in the

war on narcotics for the first time in two decades as activists,

U.N. officials and world leaders cited an international trend

towards more liberal drug laws.

Read more

BRIEF-Supersonic Imagine Q1 sales rise to 3.9 million euros

* Q1 sales 3.9 million euros ($4.43 million) versus 3.2

million euros year ago

Read more

BRIEF-Abivax gets clearance in Spain for second phase IIa trial in HIV/AIDS patients

* Abivax obtains regulatory and ethics clearance in Spain to

begin second phase iia clinical trial for ABX464 in HIV/AIDS

patients

Read more

REFILE-UN reviews war on drugs amid global push for liberalization

UNITED NATIONS, April 19 (Reuters) - The U.N. General

Assembly gathered on Tuesday to rethink global strategy in the

war on narcotics for the first time in two decades as activists,

U.N. officials and world leaders cited an international trend

towards more liberal drug laws.

Read more

BRIEF-Vetoquinol Q1 sales up at 85.8 mln euros

* Q1 2016 sales are 85.8 million euros, representing organic

growth of 7.7 pct

Source text for Eikon:

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BRIEF-J&J says does not expect Remicade to face competition from U.S. biosimilar this year

* Says in conference call that he does not expect Remicade

sales to be hurt by biosimilars this year in United States

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MIDEAST STOCKS-Saudi earnings, oil boost Gulf, Egypt breaks chart barrier

DUBAI, April 19 (Reuters) - Gulf stock markets rose on

Tuesday as several Saudi companies beat first-quarter earnings

estimates and oil prices held up better than feared after the

failure of Sunday's Doha meeting to agree on an output freeze.

Read more

Bristol-Myers' Opdivo extends survival in head and neck cancer -study

April 19 (Reuters) - Bristol-Myers Squibb's cancer

immunotherapy drug, Opdivo, helped advanced head and neck cancer

patients with a dismal prognosis live longer than other standard

treatments, according to data from a late-stage study presented

on Tuesday.

Read more

UPDATE 1-Bristol-Myers' Opdivo extends survival in head and neck cancer -study

April 19 (Reuters) - Bristol-Myers Squibb's cancer

immunotherapy drug, Opdivo, helped advanced head and neck cancer

patients with a dismal prognosis live longer than other standard

treatments, according to data from a late-stage study presented

on Tuesday.

Read more

UnitedHealth to exit all but a handful of Obamacare exchanges in 2017 -CEO

NEW YORK, April 19 (Reuters) - UnitedHealth Group Inc

Chief Executive Officer Steven Hemsley said on Tuesday

that the company would largely exit the Obamacare exchange

market in 2017, following through on a warning he had given late

last year that costs appeared to be unsustainable.

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BRIEF-Loxo Oncology announces first pediatric response to LOXO-101

* Loxo Oncology Announces First Pediatric Response to

LOXO-101, it induces 90 percent tumor regression in toddler with

refractory infantile fibrosarcoma

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BRIEF-Sucampo says to discontinue development of Cobiprostone for PPI-Refractory NERD/SGERD

* Sucampo reports top-line data from phase 2a study of

cobiprostone in patients with PPI-Refractory Non-Erosive Reflux

Disease (NERD) and Symptomatic Gastroesophageal Reflux Disease

(SGERD)

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BRIEF-RXI Pharmaceuticals says received notice of allowance for RXI-109 from USPTO

* RXI Pharmaceuticals says fortifies its novel RNAi patent

portfolio with notice of allowance for lead clinical candidate

RXI-109

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BRIEF-Cancer Prevention Pharmaceuticals sees IPO of 1.9 mln shares

April 19 (Reuters) - Cancer Prevention Pharmaceuticals Inc

Read more

RPT-DEALTALK-Debt-laden Valeant faces tough choices in asset sales

NEW YORK, April 19 (Reuters) - As Valeant Pharmaceuticals

considers a multibillion-dollar auction to pare down $30 billion

in debt, its challenge will be choosing which assets to sell

without compromising any of its key businesses, analysts and

investment bankers said.

Read more

Health insurer UnitedHealth reports higher profit

April 19 (Reuters) - Health insurer UnitedHealth Group Inc

reported a 14 percent rise in quarterly profit helped by

strength in its Optum business which offers healthcare services

and drug benefit plans.

Read more

UPDATE 1-Health insurer UnitedHealth reports better-than-expected revenue

April 19 (Reuters) - Health insurer UnitedHealth Group Inc

reported a better-than-expected quarterly revenue helped

by strength in its Optum business which offers healthcare

services and drug benefit plans.

Read more

BRIEF-Yunnan Baiyao's 2015 net profit up 10.6 pct

* Says 2015 net profit up 10.6 percent y/y at 2.8 billion

yuan ($432.63 million)

Read more

BRIEF-Eli Lilly says Jardiance to be studied for treatment of chronic heart failure

* Trials targeted to begin within next 12 months and planned

to enroll people with chronic heart failure both with and

without type 2 diabetes

Read more

BRIEF-Episurf Medical gets expanded reimbursement coverage in UK, Netherlands and Belgium

* Receives expanded reimbursement coverage in the UK, Netherlands and Belgium

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BRIEF-Huadong Medicine's Q1 net profit up 26.4 pct

* Says Q1 net profit up 26.4 percent y/y at 434.8 million

yuan ($67.19 million)

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BRIEF-Biomaxima Q1 net profit slightly up at 444,318 zlotys YoY

* Q1 revenue 6.2 million zlotys ($1.6 million) versus 5.4

million zlotys a year ago

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BRIEF-Corline Biomedical: Animal study shows Renaparin improves kidney function after transplantation

* Animal study shows that Renaparin improves kidney function after transplantation

Read more

BRIEF-Hansa Medical: recruitment completed in Phase II clinical study with IdeS in kidney transplantation

* Patient recruitment completed in Phase II clinical study with IdeS in kidney

transplantation

Read more

BRIEF-Roche CEO says IPO activity 'certainly not as active any more'

* CEO Severin Schwan says never pursues deals based on tax

considerations

Read more

Monday, April 18, 2016

BRIEF-Biofrontera says capital increase several times oversubscribed

* Said on Monday that capital increase resolved on March 29,

2016 was several times oversubscribed

Read more

BRIEF-Onxeo reports positive data for Livatag

* Reported on Monday the final data from a study aiming to

confirm the mechanism of action of Livatag

Read more

BRIEF-Biotec Pharmacon Q1 EBITDA widens to loss NOK 3.5 mln

* Q1 revenue 17.3 million Norwegian crowns ($2.11

million)versus 12.3 million crowns year ago

Read more

Sanofi invests 300 mln eur to expand Belgian plant

PARIS, April 19 (Reuters) - Sanofi said on Tuesday

that it would invest 300 million euros ($339 million) to expand

a Belgian site specialised in making treatments for rare

diseases.

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Bill Gates says U.S. needs limits on covert email searches

WASHINGTON, April 18 (Reuters) - Bill Gates said on Monday

that no one was an "absolutist" on either side of the digital

privacy debate, but the co-founder of Microsoft Corp

said he supports his company's lawsuit against the U.S.

government seeking the freedom to tell customers when federal

agencies have sought their data.

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BRIEF-Theranos says investigations or inspections were opened by CMS, FDA, SEC, and the U.S. Attorney's office for the Northern District of California

* Theranos says investigations or inspections were opened by

CMS, FDA, SEC, and the U.S. Attorney's office for the Northern

District of California

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BRIEF-Dicerna announces appointment of John Green as CFO

* Dicerna announces appointment of john "jack" green as

chief financial officer

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Theranos under investigation by SEC and U.S. Attorney's Office -Bloomberg

April 18 (Reuters) - Blood-testing firm Theranos Inc is

under investigation by the U.S. Securities and Exchange

Commission and the U.S. Attorney's Office for the Northern

District of California, Bloomberg reported.

Read more

BRIEF-Gemphire Therapeutics files for IPO of up to $60 mln

* Intend to apply to list common stock on the nasdaq global

market under the symbol "gemp"

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BRIEF-Leonard Potter reports 6.8 pct stake in Sorrento Therapeutics

* Leonard Potter reports 6.8 percent stake in Sorrento

Therapeutics Inc as of April 8 - SEC filing

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BRIEF-Dynavax presents pivotal phase 3 data showing HEPLISAV-B provides significantly higher protection against Hepatitis B than ENGERIX-B(R)

* Dynavax presents pivotal phase 3 data showing

heplisav-b(tm) provides significantly higher protection against

hepatitis b than engerix-b(r)

Read more

BRIEF-Lumos Pharma sells $34 mln in equity financing

* Says It Has Sold $34.0 Mln in equity financing - SEC

filing

Read more

What to Watch in the Day Ahead - Tuesday, April 19

(The Day Ahead is an email and PDF publication that includes the day's major stories and

events, analyses and other features. To receive The Day Ahead, Eikon users can register at

. Thomson One users can register at RT/DAY/US. All times in ET/GMT)

Johnson & Johnson is expected to report moderately higher earnings as it kicks off the

first-quarter earnings season for large U.S. drugmakers, bolstered by cost cuts and growing

sales of its treatments for cancer, arthritis and psoriasis. But investo

Read more

BRIEF-Sienna Senior Living purchases assets for about $255 mln in British Columbia

* Sienna Senior Living announces significant expansion in

British Columbia and $120 million bought deal public offering of

subscription receipts

Read more

BRIEF-Nihon Chouzai expectes operating profit of around 10 bln Yen for FY ended March 31 - Nikkei

* Nihon Chouzai is expected to report an operating profit of

around 10 bln yen ($91.9 million) for FY ended March 31 - Nikkei

Read more

BRIEF-Celator reports on previously suspended investigator-initiated clinical study

* Celator Reports On Previously Suspended

Investigator-Initiated clinical study

Read more

BRIEF-Wong Chi-Huey withdraws resignation amid insider trading probe - Nikkei

* Taiwan's Academia Sinica President Wong Chi-Huey withdrew

resignation, pledged to answer queries on insider trading probe

related to Obi Pharma - Nikkei

Source text http://s.nikkei.com/1SnltxA

Further company coverage:

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BRIEF-Amedica signs exclusive Chinese silicon nitride distribution deal

* Amedica signs exclusive Chinese silicon nitride

distribution agreement

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BRIEF-Tesaro says has sold $50 million in equity financing - SEC Filing

* Discloses in Form D with U.S. SEC that the total offering

amount was for $50 million - SEC Filing

Source - http://1.usa.gov/1NiJEhB

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BRIEF-Pieris Pharmaceuticals enters into agreement with Enumeral Biomedical Holdings

* Co entered into a license and transfer agreement with

Enumeral Biomedical Holdings

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Deals of the day- Mergers and acquisitions

April 18 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1345 GMT on Monday:

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BRIEF-Cytori Therapeutics says announced additions to patent portfolio in Japan and Europe

* Says announced today a number of key additions to its

patent portfolio in Japan and Europe

Read more

BRIEF-Geovax says MVA-VLP vaccine vector has proven safe in multiple human clinical trials

* Geovax Labs inc says "vaccine construction is progressing

rapidly" and we expect to initiate animal studies next month

Read more

BRIEF-Infinity Pharma announces new preclinical data for IPI-549

* Preclinical data demonstrate that ipi-549 targets immune

cells, alters immune-suppressive microenvironment

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BRIEF-Fibrocell Science receives allowance from U.S. FDA to initiate a phase I/II clinical trial of FCX-007 in adults

* Received allowance from u.s. Food and drug administration

(fda) to initiate a phase i/ii clinical trial of fcx-007 in

adults

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COLUMN-America's Secret Weapon

April 18 (Reuters) - This presidential election has the

country captivated. As many commentators have pointed out, the

primaries are more focused on personalities than policy. While

the parties focus on who is going to represent them in the fall,

I want to make the case for something that I hope every

candidate will agree on in November: America's unparalleled

capacity for innovation. When the United States invests in

innovation, it creates companies and jobs at home, makes

Americans healthier a

Read more

BRIEF-Chiasma updates FDA's complete response letter for Mycapssa(tm)

* Chiasma provides update regarding FDA's complete response

letter for Mycapssa(tm) new drug application

Read more

BRIEF-CytoDyn's HIV drug suppresses virus in ongoing study

April 18 (Reuters) - Cytodyn Reports Complete Viral Load

Suppression In HIV

Read more

BRIEF-Nutrition products maker Zhejiang Nhu's 2015 net profit down 50.2 pct

* Says 2015 net profit down 50.2 percent y/y at 402.1

million yuan ($62.06 million)

Read more

BRIEF-Shenzhen Salubris Pharmaceuticals' Q1 net profit up 14.1 pct

April 18 (Reuters) - Shenzhen Salubris Pharmaceuticals Co

Ltd

Read more

Is your weed killer carcinogenic?

LONDON, April 18 (Reuters) - The latest dispute to blow up

around the International Agency for Research on Cancer (IARC)

concerns glyphosate, an ingredient in one of the world's most

widely-used weed killers, Roundup, made by Monsanto.

Read more

Afghan schools, hospitals under threat, U.N. says in grim report

KABUL, April 18 (Reuters) - Schools and health facilities

have come under increasing threat as violence spreads in

Afghanistan, making it harder for children especially to get

access to education and medical care, the United Nations

reported on Monday.

Read more

BRIEF-Neurovive says large shareholder to participate in rights issue

* Neurovive: large shareholder to participate in the rights

issue

Read more

BRIEF-Bioinvent says multiple myeloma phase II study of antibody BI-505 ready to start

* Multiple myeloma phase II study of Bioinvent's antibody

BI-505 ready to start

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BRIEF-Britain's Oncimmune Holdings says to float on AIM

* Oncimmune Holdings announces intention to apply for

admission to trading on AIM

Read more

BRIEF-Xvivo Perfusion makes recommended public bid for Vivoline Medical

* Announces recommended public offer to holders of shares in Vivoline Medical

Read more

Sunday, April 17, 2016

PRESS DIGEST- British Business - April 18

April 18 (Reuters) - The following are the top stories on

the business pages of British newspapers. Reuters has not

verified these stories and does not vouch for their accuracy.

Read more

BRIEF-Shenzhen Glory Medical signs agreement on healthcare facilities projects

* Says it signs strategic agreement on healthcare facilities

projects with total investment about 600 million yuan in Henan

province

Read more

UPDATE 1-AstraZeneca has held internal talks for Medivation bid -Sunday Times

April 17 (Reuters) - Drugmaker AstraZeneca Plc has

held internal talks about a bid for cancer treatment maker

Medivation Inc but has yet to make a formal offer, the

Sunday Times reported, citing sources.

Read more

BRIEF-Astrazeneca has held internal talks about a bid for Medivation Inc looking very closely at an offer- Sunday Times, citing sources

* Astrazeneca has held internal talks about a bid for

Medivation Inc; looking very closely at an offer- Sunday Times,

citing sources

Source text : (http://bit.ly/1Sfk0Hv)

(Bengaluru Newsroom +91 80 6749-1130; within U.S. +1 646 223

8780)

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AstraZeneca has held internal talks for Medivation bid -Sunday Times

April 17 (Reuters) - Drugmaker AstraZeneca Plc has

held internal talks about a bid for Medivation Inc but

has yet to make a formal offer, the Sunday Times reported,

citing sources.

Read more

Local Zika outbreaks in United States "likely" -U.S. official

WASHINGTON, April 17 (Reuters) - The United States is likely

to see outbreaks of the Zika virus, with perhaps dozens or

scores of people affected, said Dr. Anthony Fauci, director of

the U.S. National Institute of Allergy and Infectious Diseases,

on Sunday.

Read more

RPT-Latest battle to wipe out polio begins with vast vaccine switch

LONDON, April 15 (Reuters) - In a huge immunisation effort

in 150 countries, health teams will on Sunday launch what they

hope will be the final push against polio.

Read more

Peru reports first case of sexually transmitted Zika virus

LIMA, April 16 (Reuters) - Peruvian health authorities on Saturday reported the first case of the Zika virus having been sexually transmitted in the country, after a resident contracted the disease while traveling in Venezuela and then infected his wife once back in Peru.

Read more

Saturday, April 16, 2016

Kohl raises refugee concerns before Orban meeting

BERLIN, April 16 (Reuters) - Former German Chancellor Helmut

Kohl says he does not believe Europe can absorb millions of

refugees and has appealed for more cooperation to deal with the

crisis ahead of a meeting with right-wing Hungarian Prime

Minister Viktor Orban.

Read more

REFILE-UPDATE 1-India's ITC says to resume cigarette production amid health warning row

NEW DELHI, April 16 (Reuters) - India's biggest cigarette

maker ITC Ltd said it would resume production at its

factories "consequent upon" a favourable court order, two weeks

after it decided to shutter its plants over the government's

stringent new packaging rules.

Read more

India's ITC says to resume cigarette production amid health warning row

NEW DELHI, April 16 (Reuters) - India's biggest cigarette

maker ITC Ltd will soon resume production at its

factories, the company said in a statement, two weeks after it

decided to shutter its plants over the government's stringent

new packaging rules.

Read more

Friday, April 15, 2016

UPDATE 1-U.S. FDA rejects Chiasma's drug to treat growth disorder

April 15 (Reuters) - The U.S. Food and Drug Administration

has rejected Chiasma Inc's experimental drug to treat

adults with a type of growth disorder, the company said on

Friday.

Read more

New AbbVie hepatitis C regimen shows high cure rates -studies

April 16 (Reuters) - An experimental once-daily combination

hepatitis C treatment being developed by AbbVie Inc

demonstrated very high cure rates across a wide range of disease

genotypes, according to data presented on Saturday, likely

giving the company a more competitive product if approved.

Read more

BRIEF-Chiasma receives complete response letter from FDA for Mycapssa NDA

* FDA issues complete response letter for Mycapssa new drug

application

Read more

UPDATE 1-Prince recovering after emergency plane landing due to flu-report

LOS ANGELES, April 15 (Reuters) - Singer Prince was released

from an Illinois hospital on Friday after he was hospitalized

with the flu following an emergency plane landing, celebrity

news outlet TMZ said.

Read more

BRIEF-Ligand Pharma reports 39.8 pct active stake in Viking Therapeutics

* Ligand Pharmaceuticals Incorporated reports 39.8 pct

active stake in Viking Therapeutics as of April 13, 2016 - sec

filing

Read more

U.S. FDA rejects Chiasma's drug to treat growth disorder

April 15 (Reuters) - The U.S. Food and Drug Administration

on Friday rejected Chiasma Inc's drug to treat adults

with a type of growth disorder.

Read more

BRIEF-Infusystem to acquire infusion pump assets from Infusaid

* Infusystem agrees to acquire infusion pump assets from

Infusaid Llc

Read more

BRIEF-Presbia files for mixed shelf of up to $75 million - SEC Filing

* Files for mixed shelf of up to $75 million - SEC Filing

Source - http://1.usa.gov/1WwcuND

Further company coverage:

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BRIEF-Morgan stanley reports 8.1 pct passive stake in Eagle Pharma

* Morgan Stanley reports 8.1 percent passive stake in Eagle

Pharmaceuticals Inc as of April 5, 2016 - SEC filing

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BRIEF-RXI Pharmaceuticals says reverse stock split of shares at a ratio of 1-for-10

* Announced a reverse stock split of its shares of common

stock at a ratio of 1-for-10

Read more

What to Watch in the Week Ahead and on Monday, April 18

(The Day Ahead is an email and PDF publication that includes the day's major stories and

events, analyses and other features. To receive The Day Ahead, Eikon users can register at

. Thomson One users can register at RT/DAY/US. All times in ET/GMT)

WEEK AHEAD

Markets have a number of issues to focus on next week, beginning with the outcome of Sunday's

meeting of oil ministers from the major oil producing nations. But nobody should get their hopes

up all that much for a major change in OPEC's pr

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Fitch Affirms Healthcare Realty Trust at 'BBB'; Outlook Stable

(The following statement was released by the rating agency)

NEW YORK, April 15 (Fitch) Fitch Ratings has affirmed the

ratings of Healthcare

Realty Trust (NYSE: HR) including the Issuer Default Rating

(IDR) at 'BBB'. The

Rating Outlook remains Stable. A full list of rating actions

follows at the end

of this release.

KEY RATING DRIVERS

The affirmation of HR's IDR at 'BBB' reflects the low leverage

and high

fixed-charge coverage and Fitch's view of the durability of the

operating cash

flows f

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UPDATE 1-Ivorian football star Drogba threatens legal action over attacks on his charity

DAKAR, April 15 (Thomson Reuters Foundation) - Ivorian

football star Didier Drogba has threatened legal action over

accusations that his charity set up to help children in Africa

had spent less than one percent of money raised on worthwhile

projects.

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Renata Hesse to head Justice Department's Antitrust Division

WASHINGTON, April 15 (Reuters) - Renata Hesse, who has been

in the midst of enforcing antitrust law during a surge of

aggressive corporate dealmaking, has been named to head the

Justice Department's Antitrust Division, U.S. Attorney General

Loretta Lynch said on Friday.

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UPDATE 1-India's Alkem Labs accused of fudging trial data by German regulator

MUMBAI, April 15 (Reuters) - India's Alkem Laboratories

has been accused by Germany's health regulator of

fudging data on clinical trials of an antibiotic and brain

disorder drug, becoming the third Indian firm to be scrutinised

since 2014 for suspected manipulation of trial data.

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UPDATE 1-Ex-NFL star Gault is fined in SEC fraud case, will appeal

April 15 (Reuters) - Willie Gault, the former National Football League wide receiver and Olympic sprinter, was ordered to pay $206,571 to settle a U.S. Securities and Exchange Commission lawsuit over his role in a scheme to inflate the stock price of a heart-monitoring device maker.

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BRIEF-Ose Pharma and Effimune announce signing of merger treaty

* Ose Pharma and Effimune announce the signing of the merger

treaty to create Ose Immunotherapeutics

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom:)

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BRIEF-21st Century Oncology Holdings Inc expects FY pro forma adjusted EBITDA of $155-$170 million

* Expects to report PRO FORMA adjusted EBITDA of between

$155 million and $170 million for year ended December 31, 2015

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BRIEF-PTC Therapeutics says NICE recommends Translarna for treatment of patients with nonsense mutation duchenne muscular dystrophy in England

* National institute for health and care excellence

recommended translarna for ambulatory patients with nonsense

mutation duchenne muscular dystrophy

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BRIEF-Otcpharm to liquidate DONELLE COMPANY LIMITED

* Decides to liquidate DONELLE COMPANY LIMITED

Source text for Eikon:

Further company coverage:

(Gdynia Newsroom)

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UPDATE 2-EU extends safety review of chronic hep C treatments

* Names hep C drugs from J&J, Gilead, AbbVie

(Adds details)

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Latest battle to wipe out polio begins with vast vaccine switch

LONDON, April 15 (Reuters) - In a huge immunisation effort

in 150 countries, health teams will on Sunday launch what they

hope will be the final push against polio.

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BRIEF-Ocera Therapeutics says two preclinical studies further support its ammonia scavenger OCR-002

April 15 (Reuters) - Ocera Therapeutics Announces

Presentation Of Two Preclinical Studies Further Supporting Its

Ammonia Scavenger Ocr

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BRIEF-Marinus Pharmaceuticals' ganaxolone IV receives FDA orphan drug designation

* Marinus Pharmaceuticals receives FDA orphan drug

designation for ganaxolone IV to treat status epilepticus

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WIDER IMAGE-Students run mobile amputee clinic in Syria

Maaret al-Numan, SYRIA, April 14 (Reuters) - In what looks

like an ordinary white truck, two men are helping victims who

have lost limbs in the conflict in Syria to walk, play, and even

herd sheep again.

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Deals of the day- Mergers and acquisitions

April 15 (Reuters) - The following bids, mergers,

acquisitions and disposals were reported by 1200 GMT on Friday:

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